Hasnae Boughaleb

ORCID: 0000-0002-5783-5645
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About
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Research Areas
  • Diabetes Management and Research
  • Diabetes and associated disorders
  • Pancreatic function and diabetes
  • Thermoregulation and physiological responses
  • Hemodynamic Monitoring and Therapy
  • Electron Spin Resonance Studies
  • Cardiovascular Health and Disease Prevention
  • Nitric Oxide and Endothelin Effects
  • Hormonal Regulation and Hypertension
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Medicinal Plants and Neuroprotection
  • Essential Oils and Antimicrobial Activity
  • Paraoxonase enzyme and polymorphisms
  • Cardiac, Anesthesia and Surgical Outcomes
  • Olfactory and Sensory Function Studies

UCLouvain
2022

Cliniques Universitaires Saint-Luc
2021

Abstract Purpose Pre-operative assessment of cardiovascular risk currently relies on scores, such as the American Society Anesthesiologists (ASA) score, biased towards high-risk, but neglecting middle/lower patients. Endothelial dysfunction is a precursor to events (CVEs), due impaired nitric oxide (NO) bioavailability. We previously showed that erythrocytic NO-ferroheme including 5-coordinated NO-heme-α-hemoglobin (HbNO), complex between NO and deoxyhemoglobin correlates with endothelial...

10.1007/s44254-025-00096-4 article EN cc-by Anesthesiology and Perioperative Science 2025-04-09

While the autoimmune character of T1D (type 1 diabetes) is being challenged, it currently recognized that inflammation plays a key role in its development. We hypothesized glucotoxicity could contribute to β-cell mass destruction through participation islet inflammation. evaluated potential empagliflozin (EMPA) and GABA (gamma-aminobutyric acid) protect against increase after diagnosis T1D. Empagliflozin SGLT2 (sodium-dependent glucose cotransporter) inhibitor which thereby blocks recapture...

10.1155/2019/2813489 article EN cc-by Journal of Diabetes Research 2019-07-30

Objectives To evaluate the evolution of subcutaneous glucose during two sessions monitored aerobic exercise in children or adolescents with type 1 diabetes after adaptation insulin doses and carbohydrate intake according to a combined algorithm. Methods Twelve patients (15.1 ± 2 years; duration: 9.5 3.1 years) performed series cardiac evaluation. The first (TE#1) consisted moderate vigorous intensity coupled bout maximum effort. second exercises (TE#2) was carried out real life categorized...

10.3389/fendo.2021.658311 article EN cc-by Frontiers in Endocrinology 2021-08-26
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