- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Anesthesia and Sedative Agents
- Cardiac and Coronary Surgery Techniques
- Hemodynamic Monitoring and Therapy
- Mechanical Circulatory Support Devices
- Blood transfusion and management
- Airway Management and Intubation Techniques
- Cardiac Ischemia and Reperfusion
- Cardiac Arrest and Resuscitation
- Optical Imaging and Spectroscopy Techniques
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Traumatic Brain Injury and Neurovascular Disturbances
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Aortic aneurysm repair treatments
- Ultrasound in Clinical Applications
- Erythropoietin and Anemia Treatment
- Anesthesia and Pain Management
- Congenital Diaphragmatic Hernia Studies
Cliniques Universitaires Saint-Luc
2016-2025
UCLouvain
2015-2024
KU Leuven
2005-2024
Erasmus Hospital
2023
Université Libre de Bruxelles
2023
University of Bonn
2023
Committee on Publication Ethics
2019
Wagga Wagga Base Hospital
2012
UCLouvain Saint-Louis Brussels
2004
Background Impaired cognition is a major predisposing factor for postoperative delirium, but it not systematically assessed. Anesthesia and surgery may cause delirium by affecting brain integrity. Neurofilament light in serum reflects axonal injury. Studies evaluating the perioperative course of neurofilament cardiac have shown conflicting results. The authors hypothesized that values would be higher delirious patients, baseline concentrations correlated with patients’ cognitive status...
Postoperative delirium (POD) remains a frequent complication after cardiac surgery, with pre-operative cognitive status being one of the main predisposing factors. However, performing complete neuropsychological testing is challenging. The magnitude frontal electroencephalographic (EEG) α oscillations during general anaesthesia has been related to cognition and could constitute functional marker for brain vulnerability.We hypothesised that features intra-operative α-band activity predict...
Aortic cusp free margins are a central target in most aortic valve repair operations to optimize coaptation. The objective of this anatomical study was analyse the normal dimensions margin length (FML) and coaptation surface their relationship with other root tricuspid valves.We analysed 25 homografts. Eight measurements were obtained from fresh specimens including while applying appropriate tension on structures. valves then fixed formalin diastolic position under pressure allow measurement...
BackgroundThe perioperative management of antiplatelet therapy in noncardiac surgery patients who have undergone previous percutaneous coronary intervention (PCI) remains a dilemma. Continuing dual (DAPT) may carry risk bleeding, while stopping increase the major adverse cardiovascular events (MACE).MethodsOccurrence Bleeding and Thrombosis during Antiplatelet Therapy In Non-Cardiac Surgery (OBTAIN) was an international prospective multicentre cohort study treatment, MACE, serious bleeding...
In congenital cardiac surgery, priming cardiopulmonary bypass (CPB) with fresh frozen plasma (FFP) is performed to prevent coagulation abnormalities. The hypothesis was that CPB crystalloids would be different compared FFP in terms of bleeding and/or need for blood product transfusion.In this parallel-arm double-blinded study, patients weighing between 7 and 15 kg were randomly assigned a ml · PlasmaLyte or addition predefined amount packed red cells used all patients. decision transfuse...
Anxiety can affect pregnancy rate following an in-vitro-fertilisation procedure. Hypnosis reduces emotional distress associated with medical procedures. Virtual reality (VR) is immersive 3D experience, created using a visual headset and headphones. The goal of this study was to evaluate the effect VR session without hypnosis before sedation for oocyte retrieval (OR) on anxiety levels rate.
Lagios, Marie-Hélène MD; Bidoul, Thomas Momeni, Mona MD, PhD; Khalifa, Céline PhD Author Information
Abstract Purpose Pre-operative assessment of cardiovascular risk currently relies on scores, such as the American Society Anesthesiologists (ASA) score, biased towards high-risk, but neglecting middle/lower patients. Endothelial dysfunction is a precursor to events (CVEs), due impaired nitric oxide (NO) bioavailability. We previously showed that erythrocytic NO-ferroheme including 5-coordinated NO-heme-α-hemoglobin (HbNO), complex between NO and deoxyhemoglobin correlates with endothelial...
Several studies have analyzed the long-term survival after transcatheter aortic valve implantation (TAVI). However, no previous looked at beyond 1-year with respect to type of anesthesia.The aim was evaluate mid-term TAVI anesthesia (general [GA] vs. local ± sedation [LASedation]) or procedure (transfemoral [transfem] transapical TAVI) performed.Retrospective cohort study.This retrospective study included TAVI's between January 2009 and June 2013. Patients were divided into three groups:...
To analyse our institutional results in the setting of paediatric aortic valve (AV) repair. Primary end-points were overall survival, freedom from AV reoperation and replacement.A retrospective analysis all patients under 18 years age operated on 1977 to 2015 a single tertiary care level institution. Patients included if they benefited any type repair procedure, including commissurotomy, leaflet shaving or plication, augmentation. All data gathered patients' medical records, operative...