A5116601133- Cardiac Ischemia and Reperfusion
- Essential Oils and Antimicrobial Activity
- Hemodynamic Monitoring and Therapy
- Receptor Mechanisms and Signaling
- Adipose Tissue and Metabolism
- Cardiovascular Health and Disease Prevention
- Olfactory and Sensory Function Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Medicinal Plants and Neuroprotection
Cliniques Universitaires Saint-Luc
2025
BACKGROUND: Cardiac β3-adrenergic receptors (ARs) are upregulated in diseased hearts and mediate antithetic effects to those of β1AR β2AR. β3AR agonists were recently shown protect against myocardial remodeling preclinical studies improve systolic function patients with severe heart failure. However, the underlying mechanisms remain elusive. METHODS: To dissect functional, transcriptional, metabolic effects, isolated ventricular myocytes from mice harboring a moderate, cardiac-specific...
Abstract Purpose Pre-operative assessment of cardiovascular risk currently relies on scores, such as the American Society Anesthesiologists (ASA) score, biased towards high-risk, but neglecting middle/lower patients. Endothelial dysfunction is a precursor to events (CVEs), due impaired nitric oxide (NO) bioavailability. We previously showed that erythrocytic NO-ferroheme including 5-coordinated NO-heme-α-hemoglobin (HbNO), complex between NO and deoxyhemoglobin correlates with endothelial...