A5102847953- Luminescence and Fluorescent Materials
- Molecular Sensors and Ion Detection
- Fluorine in Organic Chemistry
- Clostridium difficile and Clostridium perfringens research
- Spectroscopy Techniques in Biomedical and Chemical Research
- Environmental Sustainability in Business
- Chemical Synthesis and Analysis
- Mass Spectrometry Techniques and Applications
- Perovskite Materials and Applications
- Antimicrobial Resistance in Staphylococcus
- Nicotinic Acetylcholine Receptors Study
- Crystallography and molecular interactions
- Toxin Mechanisms and Immunotoxins
- Energy Efficiency and Management
- Organic Light-Emitting Diodes Research
- Sustainable Supply Chain Management
- Advanced Memory and Neural Computing
Fujian Institute of Microbiology
2023-2025
Western Kentucky University
2024
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Transformation of an ACQ molecule F0 into AIEgens FA, FB, and FAB through the joint strategies ring expansion N -methylation.
Dual-state emission luminogens (DSEgens), as a new type of luminescent materials that can effectively emit light in solution and solid state, have attracted tremendous attention due to their potential application chemical sensing, biological imaging, organic electronic devices, etc. In this study, two rofecoxib derivatives ROIN ROIN-B been synthesized, photophysical properties are fully investigated by experimental studies theoretical calculations. The key intermediate ROIN, resulting from...
Lipid-related cancers cause a large number of deaths worldwide. Therefore, development highly efficient Lipid droplets (LDs) fluorescent imaging probes will be beneficial to our understanding lipid-related by allowing us track the metabolic process LDs. In this work, LDs-specific NIR (λmax = 698 nm) probe, namely BY1, was rationally designed and synthesized via one-step reaction integrating triphenylamine (electron–donor group) unit into structure rofecoxib. This integration strategy enabled...
Abstract Aggregation‐induced emission luminogens (AIEgens) have been widely investigated due to their promising applications in data storage, organic light‐emitting diodes, and deep tissue bioimaging as compared conventional fluorophores. In this work, we designed synthesized two novel rofecoxib analogues functionalized with different terminal groups (−NH 2 , −Br) on the benzene ring B. Interestingly, compound a‐3 −NH substituent shows aggregation‐caused quenching effect whereas 1 b‐3 −Br...
Rakicidin B1 was isolated and purified from the culture broth of a marine Streptomyces sp. as potent anti-cancer agent, lately compound its derivatives have firstly been found to possess anti-Clostridium difficile (CD) activity but with high cytotoxicity. Herein, following our previous discovery on anti-CD B1, structure modification performed at OH position new B1-PEG hybrids FIMP2 facilely designed synthesized by conjugating PEG2000 scaffolds via linkage carbamate. The cytotoxicity first...