A5101869086- Cardiomyopathy and Myosin Studies
- Cancer Immunotherapy and Biomarkers
- Infrastructure Resilience and Vulnerability Analysis
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Immune cells in cancer
- Metastasis and carcinoma case studies
- Urban and Freight Transport Logistics
- Epigenetics and DNA Methylation
- Human Mobility and Location-Based Analysis
- Molecular Biology Techniques and Applications
- Bladder and Urothelial Cancer Treatments
- Cancer survivorship and care
- Oral and Maxillofacial Pathology
- Dialysis and Renal Disease Management
- Cancer Mechanisms and Therapy
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Inflammatory mediators and NSAID effects
- Neurogenetic and Muscular Disorders Research
- Chronic Kidney Disease and Diabetes
- Autophagy in Disease and Therapy
- Acute Lymphoblastic Leukemia research
- Helicobacter pylori-related gastroenterology studies
- Breast Cancer Treatment Studies
China Medical University
2024
First Hospital of China Medical University
2024
Harbin Institute of Technology
2023
Linyi People's Hospital
2020
Fujian Provincial Cancer Hospital
2010-2020
Fujian Medical University
2015-2020
Hebei Medical University
2012-2014
Fourth Hospital of Hebei Medical University
2012-2014
Soochow University
2013
First Affiliated Hospital of Soochow University
2013
Metastatic cancers require further diagnosis to determine their primary tumor sites. However, the tissue-of-origin for around 5% tumors could not be identified by routine medical according a statistics in United States. With development of machine learning techniques and accumulation big cancer data from The Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO), it is now feasible predict computational tools. inherits characteristics its tissue-of-origin, both gene expression profile...
The existence of cancer stem cells (CSCs) is considered as a direct reason for the failure clinic treatment in hepatocellular carcinoma (HCC). Growing evidences have demonstrated that miRNAs play an important role regulation cell proliferation, differentiation and self-renewal their aberrances cause formation CSCs eventually result carcinogenesis. We recently identified miRNA-148b one specifically down-regulated side population (SP) PLC/PRF/5 line. However, it remains elusive how regulates...
Chronic kidney disease (CKD) represents a significant global health concern, with renal fibrosis emerging as prevalent and ultimate manifestation of this condition. The absence targeted therapies presents an ongoing substantial challenge. Accumulating evidence suggests that the integrity functionality mitochondria within tubular epithelial cells (RTECs) often become compromised during CKD development, playing pivotal role in progression fibrosis. Mitophagy, specific form autophagy, assumes...
The aim of this study was to investigate the regulatory function non-coding microRNA-155 (miR-155) and suppressor cytokine signaling 1 (SOCS1) in alcoholic hepatitis (AH) its potential mechanism associated with mitogen-activated protein kinase (MAPK) pathway. Levels alanine aminotransferase (ALT), aspartate (AST), albumin (ALB), total bilirubin (TBIL), malondialdehyde (MDA), superoxide dismutase (SOD) were measured a rat model AH. biological prediction website microRNA.org dual-luciferase...
Objective To examine the reliability and validity of Chinese version Functional Assessment Cancer Therapy-Cognitive Function (FACT-Cog) in women with breast cancer. Methods The FACT-Cog was obtained by FACT.A total 202 patients cancer were investigated convenient sampling survey. The scale analyzed principal component analysis Pearson correlation analysis. Results The Cronbach α 0.96, those four dimensions 0.87-0.96. test-retest coefficients for 0.45-0.73,P<0.01.The four-factor...
Differential gene analyses on gastric cancer usually focus expression change of single genes between tumor and adjacent normal tissues. However, besides changes genes, there are also coexpression network module during the development cancer. In this study, we proposed a pipeline to investigate various levels tissues, which were used repurpose potential drugs for treating Specifically, performed series 242 samples (33-normal, 209-cancer) downloaded from genome atlas (TCGA), including data...
ABSTRACT Current neoantigen cancer vaccines activate T cell immunity through dendritic /macrophage-mediated antigen presentation. It is unclear whether incorporating B cell-mediated presentation into current could enhance CD4/CD8 to improve their anticancer efficacy. We developed a SARS-CoV-2 epitope-guided peptide/mRNA nanovaccines (B SARS NeoAg Vax) efficacy by enhancing tumor-specific antitumor Vax crosslinked with receptor, promoted CD4 cells, increased follicular/non-follicular and...
3591 Background: Metastatic cancers require further diagnosis to determine their primary tumor sites. However, the tissue-of-origin for around 5% tumors could not be identified by routine medical according. With development of machine learning techniques and accumulation big cancer data from TCGA GEO, it is now feasible predict computational tools. Methods: Developed a framework infer tissue-o. Results: Applied TOOme containing 7,008 non-metastatic samples across 20 solid including BLCA,...