- Fungal Biology and Applications
- Gut microbiota and health
- Antifungal resistance and susceptibility
- Clostridium difficile and Clostridium perfringens research
- Microbial Natural Products and Biosynthesis
- Neuroinflammation and Neurodegeneration Mechanisms
- Barrier Structure and Function Studies
- Vehicle Dynamics and Control Systems
- Plant-based Medicinal Research
- Plant Pathogens and Fungal Diseases
- Enzyme Production and Characterization
- Neonatal Respiratory Health Research
- Hearing, Cochlea, Tinnitus, Genetics
- Antimicrobial Peptides and Activities
- Supercapacitor Materials and Fabrication
- Organic Light-Emitting Diodes Research
- Gastrointestinal motility and disorders
- Oral microbiology and periodontitis research
- Railway Engineering and Dynamics
- Ginseng Biological Effects and Applications
- Berberine and alkaloids research
- Neuroscience of respiration and sleep
- Inflammatory Bowel Disease
- Herbal Medicine Research Studies
- Connexins and lens biology
Anhui University of Traditional Chinese Medicine
2023-2024
Yunnan University
2010-2023
Nanjing University of Chinese Medicine
2022
Jiangsu Province Hospital
2022
Qingdao University
2013-2021
Oregon Health & Science University
2009-2011
Affiliated Hospital of Guilin Medical College
2009
Background The endothelial-blood/tissue barrier is critical for maintaining tissue homeostasis. ear harbors a unique which we term "blood-labyrinth-barrier". This inner Disruption of the blood-labyrinth-barrier closely associated with number hearing disorders. Many proteins blood-brain-barrier and blood-retinal-barrier have been identified, leading to significant advances in understanding their specific functions. In contrast, capillaries are small volume anatomically complex. presents...
Ulcerative colitis (UC) is highly correlated with the perturbation in gut microbiota. In our previous study, unsaturated alginate oligosaccharides (UAOS), enzymatic degradation products of alginate, showed great effect on obesity prevention through regulation The aim this study was to investigate ameliorative UAOS UC induced by dextran sulfate sodium (DSS) mice models and further investigated its underlying mechanism. Herein, results a dramatic alleviation inflammatory reaction after...
Ginsenoside Rg1 is the active ingredient of plant named genus Panax (ginseng), which exhibited significant bioactivities, including anti-inflammatory, antioxidation, and anti-diabetic effects. Herein, 4-week treatment ginsenoside remarkably decreased blood glucose levels improved resistance insulin, oxidative stress, inflammation along with lipid profile in T2D rats triggered via high-fat diet streptozotocin (STZ). supplementation intestinal microbial composition induced by type 2 diabetes...
Chitosanase plays an important role in the production of chitooligosaccharides (CHOS), which possess various biological activities. Herein, a glycoside hydrolase (GH) family 46 chitosanase-encoding gene, csnB, was cloned from marine bacterium Bacillus sp. BY01 and heterologously expressed Escherichia coli. The recombinant chitosanase, CsnB, optimally active at 35 °C pH 5.0. It also revealed to be cold-adapted enzyme, maintaining 39.5% 40.4% its maximum activity 0 10 °C, respectively....
Single-component WLEDs with tunable CCT from 3303 to 8055 K and very high CRI >90 have been realized using ZnO-QDs as emissive layer, which opens up a new avenue for the development of low-cost, environment-friendly, high-performance single-component WLEDs.
Abstract Two new sesquiterpenes, stereumin F ( 1 ) and G 2 ), together with two known compounds (3 β ,5 α ,22 E ,24 R )‐5,8‐epidioxyergosta‐6,22‐dien‐3‐ol 3 4‐(2‐hydroxyethyl)phenol 4 were isolated from the AcOEt extract of culture broth MeOH mycelium fungal strain Stereum sp. CCTCC AF 207024. Their structures established on basis spectral analyses.
We aimed to elucidate the synergistic effect and potential mechanism of New Baitouweng Decoction (NBD) combined with fecal microbiota transplantation (FMT) in rats DSS-induced ulcerative colitis (UC).Colitis was induced by 5% (w/v) dextran sulfate sodium (DSS) drinking water for 7 days. NBD or FMT were administered rats. Body weight disease activity index measured, colon histological change imaged further examine efficacy FMT. The specific effects on STAT3/NF-κB signaling pathway gut UC also...
Transduction of sound in the inner ear demands tight control over delivery oxygen and glucose. However, mechanisms underlying regional blood flow are not yet fully understood. In this study, we report a novel local mechanism that regulates cochlear to stria vascularis, high energy-consuming region ear. We found extracellular lactate had vasodilatory effect on capillaries spiral ligament under both vitro vivo conditions. The lactate, acting through monocarboxylate transporter 1 (MCT1),...
Abstract The front cover artwork is provided by Mr. Xu Liu and Prof. Yude Wang from Yunnan University (Kunming, P.R. China). image shows the green corrosion route water Ni foam to a Ni(OH) 2 @Ni binder‐free supercapacitor electrode. Read full text of Article at 10.1002/celc.201701094 .
In order to study the road friendliness of heavy vehicle under bilateral tracks’ excitation, spatial domain random pavement excitation was simulated through second-order rational function power spectral density (PSD) and harmonic superposition method. A rigid-flexible coupling virtual prototype established by using SIMPACK software. Then a driving dynamic model excitation. The tires loads vehicle’s each axle were calculated. load coefficient (DLC) 95 percentage fourth aggregate force used as...
Among the diverse fungal opportunistic pathogens,
Abstract The isolation and structure elucidation of two novel sesquiterpenes, stereumin F (I) G (II), are reported.