Ligang Zhou

ORCID: 0000-0003-4681-191X
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Research Areas
  • Microbial Natural Products and Biosynthesis
  • Fungal Biology and Applications
  • Plant Pathogens and Fungal Diseases
  • Essential Oils and Antimicrobial Activity
  • Insect Pest Control Strategies
  • Mycotoxins in Agriculture and Food
  • Phytochemistry and Biological Activities
  • Insect and Pesticide Research
  • Natural product bioactivities and synthesis
  • Plant-Microbe Interactions and Immunity
  • Chemical synthesis and alkaloids
  • Plant tissue culture and regeneration
  • Particle physics theoretical and experimental studies
  • Plant and fungal interactions
  • Phytochemical compounds biological activities
  • Ginseng Biological Effects and Applications
  • Marine Sponges and Natural Products
  • Quantum Chromodynamics and Particle Interactions
  • High-Energy Particle Collisions Research
  • Phytochemical Studies and Bioactivities
  • Chromatography in Natural Products
  • Traditional and Medicinal Uses of Annonaceae
  • Phytochemicals and Antioxidant Activities
  • Plant biochemistry and biosynthesis
  • Alkaloids: synthesis and pharmacology

China Agricultural University
2016-2025

Sichuan University
2025

Third Xiangya Hospital
2025

Central South University
2025

Tianjin Medical University
2024

Xi'an Shiyou University
2024

Guangdong University of Foreign Studies
2023

State Council of the People's Republic of China
2020

Institute of Plant Protection
2016-2020

Shanghai Electric (China)
2020

Plant endophytic fungi are an important and novel resource of natural bioactive compounds with their potential applications in agriculture, medicine food industry. In the past two decades, many valuable antimicrobial, insecticidal, cytotoxic, anticancer activities have been successfully discovered from fungi. During long period co-evolution, a friendly relationship was formed between each endophyte its host plant. Some endophytes ability to produce same or similar as those originated plants....

10.2174/138955711794519492 article EN Mini-Reviews in Medicinal Chemistry 2011-02-01

Ustilaginoidea virens (Cooke) Takah is an ascomycetous fungus that causes rice false smut, a devastating emerging disease worldwide. Here we report 39.4 Mb draft genome sequence of U. encodes 8,426 predicted genes. The has ~25% repetitive sequences have been affected by repeat-induced point mutations. Evolutionarily, close to the entomopathogenic Metarhizium spp., suggesting potential host jumping across kingdoms. possesses reduced gene inventories for polysaccharide degradation, nutrient...

10.1038/ncomms4849 article EN cc-by-nc-sa Nature Communications 2014-05-20

To examine in vivo a rodent model the potential role of AMP-activated protein kinase (AMPK) within ventromedial hypothalamus (VMH) glucose sensing during hypoglycemia.Using gene silencing technology to selectively downregulate AMPK VMH, key hypothalamic glucose-sensing region, we demonstrate for detection hypoglycemia. In hyperinsulinemic-hypoglycemic (50 mg dl(-1)) clamp studies were performed awake, chronically catheterized Sprague-Dawley rats that had been microinjected bilaterally VMH...

10.2337/db07-0837 article EN Diabetes 2007-11-01

Three steroids and one nordammarane triterpenoid were isolated for the first time from endophytic fungus Pichia guilliermondii Ppf9 derived medicinal plant Paris polyphylla var. yunnanensis. By means of physicochemical spectrometric analysis, they identified as ergosta-5,7,22-trienol (1), 5α,8α-epidioxyergosta-6,22-dien-3β-ol (2), ergosta-7,22-dien-3β,5α,6β-triol (3), helvolic acid (4). Both micro-dilution-colorimetric spore germination assays employed to evaluate their antimicrobial...

10.3390/molecules15117961 article EN cc-by Molecules 2010-11-05

Seven flavonoids have been isolated from the aerial parts of Halostachys caspica C. A. Mey. (Chenopodiaceae) for first time. By means physicochemical and spectrometric analysis, they were identified as luteolin (1), chrysin (2), 7-O-β-D-glucopyranoside (3), quercetin (4), 3-O-β-D-glucopyranoside (5), isorhamentin-3-O-β-D-glucopyranoside (6), isorhamentin-3-O-β-D-rutinoside (7). All evaluated to show a broad antimicrobial spectrum activity on microorganisms including seven bacterial one...

10.3390/molecules15117933 article EN cc-by Molecules 2010-11-05

The screening for bioactive principles from several Chinese medicinal herbs showed that the essential oil of Cymbopogon distans aerial parts possessed strong repellency against booklouse, Liposcelis bostrychophila , and red flour beetle, Tribolium castaneum . A total 36 components were identified by GC GC-MS. trans-Geraniol (16.54%), (R)-citronellal (15.44%), (+)-citronellol (11.51%), α-elemol (9.06%) main followed β-eudesmol (5.71%) (+)-limonene (5.05%). From oil, four monoterpenes isolated...

10.1021/jf202266n article EN Journal of Agricultural and Food Chemistry 2011-08-05

During our screening program for agrochemicals from Chinese medicinal herbs and wild plants, the essential oil of Carum carvi fruits was found to possess strong contact toxicity against Sitophilus zeamais Tribolium castaneum adults, with LD50 values 3.07 3.29 mg/adult, respectively, also showed fumigant two grain storage insects LC50 3.37 2.53 mg/L, respectively. The obtained by hydrodistillation investigated GC GC-MS. main components were identified be (R)-carvone (37.98%) D-limonene...

10.3390/molecules15129391 article EN cc-by Molecules 2010-12-20

In order to identify natural products for plant disease control, the essential oil of star anise (Illicium verum Hook. f.) fruit was investigated its antifungal activity on pathogenic fungi. The obtained by hydro-distillation analyzed chemical composition gas chromatography (GC) and chromatography-mass spectrometry (GC-MS). trans-Anethole (89.5%), 2-(1-cyclopentenyl)-furan (0.9%) cis-anethole (0.7%) were found be main components among 22 identified compounds, which accounted 94.6% total oil....

10.3390/molecules15117558 article EN cc-by Molecules 2010-10-27

The aim of this research was to determine the chemical composition essential oil Acorus calamus rhizomes, its insecticidal activity against booklouse, (Liposcelis bostrychophila) and isolate any constituents from oil. A. rhizomes obtained by hydrodistillation analyzed GC-FID GC-MS. A total 32 components identified principal compounds in were determined be α-asarone (50.09%), (E)-methylisoeugenol (14.01%), methyleugenol (8.59%), followed β-asarone (3.51%), α-cedrene (3.09%) camphor (2.42%)....

10.3390/molecules18055684 article EN cc-by Molecules 2013-05-15

Ustiloxins are a group of cyclopeptide mycotoxins produced by rice false smut pathogen Villosiclava virens (anamorph: Ustilaginoidea virens) which seriously threaten the safety production and health humans livestock. Ustiloxin A, accounting for 60% total ustiloxins, is main toxic component. Biotransformation, process modifying functional groups compounds means regio- or stereo-specific reactions catalyzed enzymes organisms, has been considered as an efficient way to detoxify mycotoxins. In...

10.3390/toxins17020048 article EN cc-by Toxins 2025-01-22

Summary In order to learn how 1‐methylcyclopropene (1‐MCP) affects ripening and disease‐resistance of peach fruit ( Prunus persica L. cv. Jiubao) after harvest, they were treated with 1‐MCP some inoculated Penicillium expansum . Treating 0.2 μ L −1 at 22 °C for 24 h effectively slowed the decline in firmness. The minimal concentration able inhibit softening was 0.6 Changes other parameters related ripening, such as content soluble solids, total sugar, titratable acidity, pectin ethylene...

10.1111/j.1365-2621.2004.00905.x article EN International Journal of Food Science & Technology 2005-01-01
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