A5050469178- Cell Image Analysis Techniques
- Carcinogens and Genotoxicity Assessment
- Molecular Biology Techniques and Applications
- Advanced Proteomics Techniques and Applications
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Genetics, Bioinformatics, and Biomedical Research
- Machine Learning and Data Classification
- Gene Regulatory Network Analysis
- Bioinformatics and Genomic Networks
- Diabetes Treatment and Management
- Lipoproteins and Cardiovascular Health
HUN-REN Szegedi Biológiai Kutatóközpont
2020-2023
Precise spatiotemporal protein organization is critical for fundamental biological processes including cell division. Indeed, aberrant mitosis and mitotic factors are involved in diverse diseases, various cancers, Alzheimer's disease, rare diseases. During mitosis, complex spatial rearrangements regulation ensure the accurate separation of replicated sister chromatids to produce genetically identical daughter cells. Previous studies employed high-throughput methodologies follow specific...
Abstract Biological processes are inherently continuous, and the chance of phenotypic discovery is significantly restricted by discretising them. Using multi-parametric active regression we introduce Regression Plane (RP), a user-friendly tool enabling class-free supervised machine learning, to describe explore biological data in continuous manner. First, compare traditional classification with simulated experimental setup. Second, use our framework identify genes involved regulating...
Comet assay provides an easy solution to estimate DNA damage in single cells through microscopy assessment. It is widely used the analysis of genotoxic damages induced by radiotherapy or chemotherapeutic agents. quantified at single-cell level computing displacement between genetic material within nucleus, typically called "comet head", and surrounding part cell, considered as tail". Today, number works based on Assay analyses really impressive. In this work, besides revising solutions...
ABSTRACT Biological processes are inherently continuous, and the chance of phenotypic discovery is significantly restricted by discretising them. Using multi-parametric active regression we introduce a novel concept to describe explore biological data in continuous manner. We have implemented Regression Plane (RP) , first user-friendly tool enabling class-free supervised machine learning.
ABSTRACT Comet assay provides an easy solution to estimate DNA damage in single cells through microscopy assessment. It is widely used the analysis of genotoxic damages induced by radiotherapy or chemotherapeutic agents. quantified at single-cell level computing displacement between genetic material within nucleus, typically called “comet head”, and surrounding part cell, considered as tail”. Today, number works based on Assay analyses really impressive. In this work, besides revising...