A5035485316- Erythropoietin and Anemia Treatment
- Endoplasmic Reticulum Stress and Disease
- Iron Metabolism and Disorders
- Mitochondrial Function and Pathology
- MicroRNA in disease regulation
- Flavonoids in Medical Research
- Chemotherapy-induced organ toxicity mitigation
- Intramuscular injections and effects
- Medicinal Plants and Bioactive Compounds
- Rheumatoid Arthritis Research and Therapies
- Inflammasome and immune disorders
- RNA modifications and cancer
- Osteoarthritis Treatment and Mechanisms
- Adipose Tissue and Metabolism
- Ferroptosis and cancer prognosis
- Chemotherapy-induced cardiotoxicity and mitigation
- Acute Lymphoblastic Leukemia research
- Hemoglobinopathies and Related Disorders
Tanta University
2023-2025
Doxorubicin (DOX)-induced cardiotoxicity (DIC) is a life-threatening clinical issue with limited preventive approaches, posing substantial challenge to cancer survivors. The anthraquinone diacerein (DCN) exhibits significant anti-inflammatory, anti-proliferative, and antioxidant actions. Its beneficial effects on DIC have yet be clarified. Therefore, this study investigated DCN’s cardioprotective potency its conceivable molecular targets against DIC. Twenty-eight Wister rats were assigned...
Polycystic ovarian syndrome (PCOS) is a multifaceted metabolic and hormonal disorder in females of reproductive age, frequently associated with cardiac disturbances. This research aimed to explore the protective potential adropin and/or tirzepatide (Tirze) on cardiometabolic aberrations letrozole-induced PCOS model. Female Wistar non-pregnant rats were allotted into five groups: CON; PCOS; + adropin; Tirze; adropin+ Tirze. The serum sex hormones, glucose, lipid profiles securitized. Cardiac...
Background: Osteoarthritis (OA) is a chronic protracted inflammatory joint disorder that frequently coexists with other comorbidities.Previous studies analyzed peptidase activity in synovial fluid knee OA (KOA) patients, but they did not investigate whether type of therapy influences enzyme activity.Moreover, it yet unknown if the any particular can be taken into account as reliable prognostic marker for severity and progression KOA.Objective: The aim current study to assess peptidase's...