A5037877113- Meningioma and schwannoma management
- Advances in Oncology and Radiotherapy
- Neurofibromatosis and Schwannoma Cases
- Economic and Financial Impacts of Cancer
- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Glioma Diagnosis and Treatment
- Telemedicine and Telehealth Implementation
- Radiation Dose and Imaging
- Lung Cancer Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Tracheal and airway disorders
- Brain Metastases and Treatment
- Palliative Care and End-of-Life Issues
- Cancer Genomics and Diagnostics
- Global Cancer Incidence and Screening
- Innovations in Medical Education
- Cancer survivorship and care
- CAR-T cell therapy research
- Head and Neck Surgical Oncology
- Head and Neck Cancer Studies
- Pituitary Gland Disorders and Treatments
- CNS Lymphoma Diagnosis and Treatment
- Advanced Radiotherapy Techniques
- Diversity and Career in Medicine
University of Münster
2025
Thomas Jefferson University
2019-2023
Sidney Kimmel Cancer Center
2019-2023
Thomas Jefferson University Hospital
2022
Wills Eye Hospital
2021
Neurological Surgery
2020
University of Chicago
2016-2019
University of Illinois Chicago
2014-2016
Sorbonne Université
2011-2014
Université Paris-Sud
2014
Abstract Successful combinations of radiotherapy and immunotherapy depend on the presence live T cells within tumor; however, is believed to damage cells. Here, based longitudinal in vivo imaging functional analysis, we report that a large proportion survive clinically relevant doses radiation show increased motility, higher production interferon gamma, compared with from unirradiated tumors. Irradiated intratumoral can mediate tumor control without newly-infiltrating Transcriptomic analysis...
Abstract Purpose: African Americans (AA) have the highest incidence of colorectal cancer compared with other U.S. populations and more proximal cancers. The objective is to elucidate basis these disparities. Experimental design: Of note, 566 AA 328 non-Hispanic White (NHW) cancers were ascertained in five Chicago hospitals. Clinical exposure data collected. Microsatellite instability (MSI) BRAF (V600E) KRAS mutations tested. Statistical significance categorical variables was tested by Fisher...
<title>Abstract</title> Inflammatory cardiovascular diseases are the leading cause of death worldwide. Neutrophils, key drivers during inflammation, have consistently been associated with adverse outcomes and mortality in pathologies. Given uniquely high plasticity turnover neutrophils, we profiled appearance distinct neutrophil maturation stages as sensitive specific biomarkers patients ST-elevation myocardial infarction (STEMI), heart failure stroke. Our data reveal a neutrophilia driven...
Dural tails are thickened contrast-enhancing portions of dura associated with some meningiomas. Prior studies have demonstrated the presence tumor cells within dural tail, however their inclusion in radiation treatment fields remains controversial. We evaluated role including tail when treating a meningioma stereotactic and impact on recurrence.This is retrospective, single-institution, cohort study patients intracranial World Health Organization (WHO) grade 1 identified who were treated...
Abstract Intralobar pulmonary sequestration (ILPS) and bronchogenic cyst are rare congenital diseases. We present the first case of association between an ILPS located in upper lobe a cyst. This has been discovered antenatally girl. The cystic lesion shown by fetal MRI confirmed CT scan at 3 weeks life. She underwent left lobectomy thoracoscopy age 5 months. Postoperative course was uneventfull. confirms origin shows interest early surgery. Pediatr. Pulmonol. 2011; 46:509–511. © 2010 Wiley‐Liss, Inc.
PURPOSE Modern wearable devices provide objective and continuous activity data that could be leveraged to enhance cancer care. We prospectively studied the feasibility of monitoring physical using a commercial device collecting electronic patient-reported outcomes (ePROs) during radiotherapy (RT) for head neck (HNC). METHODS Patients planned course external beam RT with curative intent HNC were instructed use fitness tracker throughout course. During weekly clinic visits, physician-scored...
Abstract: Tumor-to-tumor metastasis describes the ability of primary tumors to metastasize other tumors. These events generally occur in aggressive and widely-metastatic disease, with appropriate management significance these unknown. A 56-year-old woman a history bilateral, localized, invasive lobular breast carcinoma treated surgery, systemic therapy, adjuvant radiation presented five two years post-treatment progressive neurological symptoms. Imaging revealed an intracranial meningioma,...
Background: The first line definitive treatment for early-stage indolent B-cell lymphoma is radiation therapy (RT). Due to the sensitivity of orbital structures radiation, ultra-low-dose RT (4 Gy in 2 fractions, "boom-boom") has and been utilized as an attractive option lymphoma. In this retrospective study, we evaluated outcome toxicity "boom-boom" with emphasis on ophthalmologic toxicity. Methods: This a case series 17 patients who received boom-boom at single tertiary referral center...
The possible role of melatonin in the regulation reproductive system female rats during ageing was investigated middle-aged showing irregular duration oestrous cycle (n = 30). Blood samples were obtained by jugular venepuncture control rats. After this experiment completed, treated with for 2 months and blood at different stages cycle. Plasma LH, FSH prolactin concentrations significantly increased afternoon day pro-oestrus after treatment compared Moreover, too on morning oestrus Similarly,...
Cowden's Syndrome (CS) is a rare disease with increased risk for several carcinomas. Experimental studies and limited case reports have described the negative effects of radiotherapy. A 35-yearold woman presented newly diagnosed CS multiple meningiomas. She underwent subtotal resection right petroclival meningioma to relieve brainstem compression received adjuvant fractionated stereotactic radiotherapy 50 Gy in 25 fractions minimal side effects. Twenty months post-operatively patient...
Meningeal melanocytomas are rare, benign tumours of the central nervous system arising from melanocytes leptomeninges. First-line treatment consists either gross or subtotal resection with without radiotherapy. However, given sensitive locations these tumours, alternative options such as definitive radiotherapy may be warranted in patients deemed high-risk accessible tumours. A 67-year-old male presenting spastic gait, frequent falls, and vertical gaze palsy was diagnosed a 2.4 cm primary...
Carcinosarcoma is a malignant mixed tumor composed of epithelial and mesenchymal components which arises in variety tissues, including, rare cases, the orbit. A 75-year-old male with history basal cell carcinoma left medial canthus, previously treated surgical resection adjuvant radiation therapy, presented recurrent 3 cm nodule canthus. He underwent superior inferior eyelid pathology revealing invasive squamous upper lower eyelids deep orbital tissue involvement undifferentiated pleomorphic...