A5101489272- Inflammatory Bowel Disease
- Gut microbiota and health
- Circular RNAs in diseases
- Genetic factors in colorectal cancer
- Colorectal Cancer Screening and Detection
- Helicobacter pylori-related gastroenterology studies
- MicroRNA in disease regulation
- Immune Response and Inflammation
- Peptidase Inhibition and Analysis
- Cancer Mechanisms and Therapy
- Probiotics and Fermented Foods
- Cancer-related gene regulation
- Gastric Cancer Management and Outcomes
- Cancer-related molecular mechanisms research
- High Entropy Alloys Studies
- Mechanisms of cancer metastasis
- Cancer, Hypoxia, and Metabolism
- Enzyme Structure and Function
- Wnt/β-catenin signaling in development and cancer
- Mitochondrial Function and Pathology
- ATP Synthase and ATPases Research
- Nanoparticle-Based Drug Delivery
- Kruppel-like factors research
- Cancer Research and Treatments
- Colorectal and Anal Carcinomas
Shandong Tumor Hospital
2014-2022
Shandong First Medical University
2014-2022
Qiqihar Medical University
2015-2020
Shandong Academy of Sciences
2020
Shandong Center for Disease Control and Prevention
2019
Abstract Background and Aims Stool DNA testing is an emerging attractive option for colorectal cancer (CRC) screening. We previously evaluated the feasibility of a stool (sDNA) test methylated SDC2 CRC detection. The aim this study was to assess its performance in multicenter clinical trial setting. Methods Each participant required undergo sDNA reference colonoscopy. consists quantitative assessment methylation status promoter. Results real-time methylation-specific PCR were dichotomized as...
The purpose of this study was to explore the potential early diagnostic value serum microRNA-381(miRNA-381) in patients with gastric cancer (GC). Patients advanced (AGC) and (EGC), as well healthy individuals, were enrolled study. Expression miRNA-381 detected using real-time quantitative PCR. Electrochemiluminescence analysis used investigate expression classic tumor markers, including carbohydrate antigen (CA) 199, CA724, carcinoembryonic antigen. Finally, receiver operating characteristic...
Background: We aimed to investigate the effect of probiotic VSL#3 on NF-κB and TNF-α in rats with colitis correlation TLR4-NF-κB signal pathway. Methods: Sixty Sprague Dawley (SD) were divided into control, model therapy groups (n=20) according random number table. Rats modeled for colitis, group intragastrically administered VSL#3. The expression TLR4 protein, levels NF-κB, TLR4, mRNA colon tissue detected. concentration serum after modeling but before intragastric administration (T0), 3d...