A5007903286- Radiation Therapy and Dosimetry
- Advanced Radiotherapy Techniques
- Radiation Dose and Imaging
- DNA Repair Mechanisms
- Radiation Effects and Dosimetry
- Radiation Detection and Scintillator Technologies
- Eosinophilic Esophagitis
- Childhood Cancer Survivors' Quality of Life
- Medical Imaging Techniques and Applications
- Advances in Oncology and Radiotherapy
- Lung Cancer Diagnosis and Treatment
- Management of metastatic bone disease
- Radiation Effects in Electronics
- Acute Lymphoblastic Leukemia research
- Diverse Music Education Insights
- Counseling Practices and Supervision
- Economic and Environmental Valuation
- Carcinogens and Genotoxicity Assessment
- Platelet Disorders and Treatments
- Simulation-Based Education in Healthcare
- Urban Green Space and Health
- Glioma Diagnosis and Treatment
- Empathy and Medical Education
- Nuclear Physics and Applications
- Nuclear reactor physics and engineering
Baptist Hospital of Miami
2025
Baptist Health South Florida
2024-2025
Florida International University
2024-2025
Miami Heart Research Institute
2024
Cancer Institute (WIA)
2024
University of Alabama at Birmingham
2021
University of California, San Diego
2019-2021
The University of Texas Health Science Center at San Antonio
2017-2020
Lakehead University
2020
Atrium Health Wake Forest Baptist
2018
Abstract Purpose Historically, the process of positioning a patient prior to imaging verification used set permanent marks, or tattoos, placed subcutaneously. After aligning these plan specific shifts are applied and position is verified with imaging, such as cone‐beam computed tomography ( CBCT ). Due variety factors, marks may deviate from desired it be hard align marks. Surface‐based systems an alternative method verifying initial entire skin surface instead tattoos. The aim this study...
Abstract Objectives The challenges of bioscience courses such as anatomy and physiology in nursing education are well documented. Virtual reality has recently become accessible may support student engagement. purpose this project was to describe students’ engagement experiences with virtual a first-year course on anatomy, physiology, health assessment. Methods We used cross-sectional design collected both quantitative qualitative data. Exploratory Learning Model guided our work. Results...
Purpose This study aims to standardize the simulation procedure in measuring DNA double‐strand breaks ( DSB s), by using advanced Monte Carlo toolkits, and newly introduced experimental methods for measurement. Methods For quantification of , an innovative dosimeter was used produce data. GATE combination with Geant4‐ toolkit were exploited simulate environment. The PDB 4 example upgraded investigated. Parameters such energy threshold ET ) a strand break base pair BPT evaluated, depending on...
No formal comparative effectiveness studies have been conducted to evaluate the effect of eosinophilic esophagitis (EoE) treatment choice on long-term growth in pediatric patients. Long-term inhaled corticoid steroids asthma, however, suggest possible effects linear growth. The aim this study was compare longitudinal, anthropometric children with EoE according approach.We a retrospective, multicenter cohort (height and body mass index [BMI] z scores) (<18 years age) patients newly diagnosed...
Objectives-Differences in the initial management of pediatric eosinophilic esophagitis (EoE) by practice setting have not been well characterized.We aimed to characterize these differences for sites Carolinas EoE Collaborative (CEoEC), a multicenter network academic and community practices.Methods-We performed retrospective cohort study patients at five CEoEC sites: University North Carolina (UNC) Hospital, Charlotte Asthma Allergy Specialists, Greenville Health Systems, Wake Forest Baptist...
Many types of dosimeters are used to measure radiation dose and calibrate radiotherapy equipment, but none directly the biological effect this dose. The purpose here is create a dosimeter that can probability double-strand breaks (DSB) for DNA, which related radiation.A DNA dosimeter, consisting magnetic streptavidin beads attached four kilobase pair strands labeled with biotin fluorescein amidite (FAM) on opposing ends, was suspended in phosphate-buffered saline (PBS). Fifty microliter...
Purpose The Halcyon consists of precommissioned linear accelerator and treatment planning algorithms that were designed to simplify the acceptance, commissioning, clinical workflow for image‐guided intensity‐modulated radiotherapy. purpose this work was perform a comprehensive safety assessment use Halcyon. Methods Systems‐Theoretic Process Analysis used as tool. As part analysis, number control loops actions are created describe system function. Safety is assessed by determining unsafe...
Introduction:With the advent of complex treatment techniques like volumetric modulated arc therapy, there has been increasing interest in planning technologies aimed at reducing time. One these such is auto-planning, which an automated module within Pinnacle3. This study seeks to retrospectively evaluate dosimetric quality auto-planning-derived plans as they compare manual for intact prostate, prostate and lymph nodes, brain sites. Materials Methods:Previous clinical were used generate...
In this work, we developed a DNA dosimeter, consisting of 4-kb strands attached to magnetic streptavidin beads and labeled with fluorescein, detect double-strand breaks (DSBs). The purpose here was evaluate whether the dosimeter readings reflect relative biological effects 160 kVp 6 MV X rays. AVarian 600 C/D linac (6 MV) Faxitron cabinet X-ray system (160 kVp), both calibrated using traceable methods, were used deliver high- low-energy photons, respectively, dosimeters multiple cell lines...
Abstract Purpose In growing children, craniospinal irradiation (CSI) has historically treated the entire vertebral body (VB) to avoid potential long‐term spinal abnormalities. Vertebral body‐sparing proton (VBSpCSI) is a technique that spares majority of VB from significant irradiation, and safety outcomes have been reported previously. This retrospective study reviews acute toxicity profile children with VBSpCSI in cohort comparison photon‐based radiotherapy (3DCRT). Methods Thirty‐eight...
Purpose The purpose of this study was to assess the treatment planning feasibility volumetrically modulated arc therapy total body irradiation (VMAT TBI) using a simultaneous integrated marrow and approach (SIMBa). We also aimed compare SIMBa TBI with more conventional VMAT entire as target. goal an like is balance known clinical benefit toxicity decrease Total Marrow Irradiation (TMI) two prescription volumes. In anticipation trial investigate novel conditioning regimen that uses SIMBa, our...
We developed a dosimeter that measures biological damage following delivery of therapeutic beams in the form double-strand breaks (DSBs) to DNA. The contains DNA strands are labeled on one end with biotin and other fluorescein attached magnetic microbeads. Following irradiation, magnet is used separate broken from unbroken strands. Then, fluorescence utilized measure relative amount determine probability for DSB. long-term goal this research evaluate whether type biologically based holds any...
To provide a methodology for characterization of the technical properties newly developed non-metallic tissue expander intensity modulated proton therapy.
The use of hydroxy-ethyl starch (HES) has been used in the cord blood banking industry for separation into its individual components. focus this study is to examine whether HES feasible obtaining a buffy coat construction platelet gels. Blood was collected from seven canines anticoagulant citrate dextrose at ratio 1:8. A sample whole obtain initial cell counts and base line Thrombelastograph (TEG). 6% Hespan added allowed sediment 60 minutes. Cell TEGs were performed on resulting layers: red...
Abstract Purpose Dose–volume histogram (DVH) measurements have been integrated into commercially available quality assurance systems to provide a metric for evaluating accuracy of delivery in addition gamma analysis. We hypothesize that tumor control probability and normal tissue complication calculations can additional insight beyond conventional dose verification methods. Methods A commercial system was used generate DVHs treatment plan using the planning CT images patient‐specific QA on...
Proton radiotherapy treatment planning systems use a constant relative biological effectiveness (RBE) = 1.1 to convert proton absorbed dose into biologically equivalent high-energy photon dose. This method ignores linear energy transfer (LET) distributions, and RBE is known change as function of LET. Variable approaches have been proposed for optimization. Experimental validation models underlying these pre-requisite their clinical implementation. has probe every level in the evolution...
The Elekta Active Breathing CoordinatorTM (ABC) is used to control breathing and guide deep inspiration breath hold (DIBH). It has been shown be accurate in lung cancers, but limited analysis performed on the spatial accuracy reproducibility of breast surface. use optical surface-image guidance for patient positioning grown popularity an alternative solution DIBH. This study aims evaluate surface variability ABC-guided DIBH by using a three-dimensional (3D) imaging system record position.