A5039661629- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiation Therapy and Dosimetry
- Radiation Dose and Imaging
- Advances in Oncology and Radiotherapy
- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Advanced X-ray and CT Imaging
- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Management of metastatic bone disease
- Atomic and Molecular Physics
- Head and Neck Cancer Studies
- Prostate Cancer Diagnosis and Treatment
- Meningioma and schwannoma management
- Advanced Chemical Physics Studies
- Endometrial and Cervical Cancer Treatments
- Breast Cancer Treatment Studies
- Advanced MRI Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Neurological disorders and treatments
- Mass Spectrometry Techniques and Applications
- Prostate Cancer Treatment and Research
- Cold Atom Physics and Bose-Einstein Condensates
- Digital Radiography and Breast Imaging
University of Alabama at Birmingham
2016-2025
University of Michigan
2015-2022
University of Wisconsin System
2018
WinnMed
2018
Swedish Medical Center
2018
American Association of Physicists in Medicine
2018
John Wiley & Sons (United States)
2018
University of Alabama
2006-2015
The University of Texas MD Anderson Cancer Center
2000-2012
Seoul National University Hospital
2006
Abstract Purpose Online Adaptive Radiation Therapy (oART) follows a different treatment paradigm than conventional radiotherapy, and because of this, the resources, implementation, workflows needed are unique. The purpose this report is to outline our institution's experience establishing, organizing, implementing an oART program using Ethos therapy system. Methods We include resources used, operational models utilized, creation timelines, institutional experiences with implementation...
Volumetric modulated arc therapy (VMAT) has been shown to be feasible for radiosurgical treatment of multiple cranial lesions with a single isocenter.To investigate whether equivalent plan quality and reduced delivery time could achieved in VMAT patients intracranial targets previously treated Gamma Knife (GK) radiosurgery.We identified 28 GK treatments metastases. These were replanned multiarc single-arc, single-isocenter (RapidArc) Eclipse. The prescription all was standardized 18 Gy. Each...
This report describes the current state of flattening filter‐free (FFF) radiotherapy beams implemented on conventional linear accelerators, and is aimed primarily at practicing medical physicists. The Therapy Emerging Technology Assessment Work Group American Association Physicists in Medicine (AAPM) formed a writing group to assess FFF technology. published literature technology was reviewed, along with technical specifications provided by vendors. Based this information, supplemented...
Intensity modulated radiation therapy (IMRT) with a dynamic multileaf collimator (DMLC) requires synchronization of DMLC leaf motion dose delivery. A delay in communication is known to cause lag and lead dosimetric errors. The errors may be exacerbated by gated operation. purpose this study was investigate the effect on accuracy doses delivered IMRT. We first determined effective time measuring stationary phantom wedge-shaped fields. wedge fields were generated at various rates. so varied...
Retroperitoneal sarcomas (RPSs) are rare tumors with poor survival rates due to difficult resectability and high local distant recurrence rates. Preoperative radiation therapy appears have dosimetric advantages utilize the tumor as a tissue expander limit exposure of small bowel higher doses.Between June 1999 December 2003, 16 consecutive patients biopsy-proven RPS were treated preoperative selective dose escalation. This included 45 grays (Gy) in 25 fractions entire plus margin boost 57.5...
Stereotactic body radiation therapy (SBRT) employs precision target tracking and image-guidance techniques to deliver ablative doses of localized malignancies; however, treatment with conventional photon beams requires lengthy immobilization times. The use flattening filter-free (FFF) operating at higher dose rates can shorten beam-on time, we hypothesize that it will overall delivery time. A total 111 lung liver SBRT cases treated our institution from July 2008 2011 were reviewed 99...
Limited data exist on fractionated stereotactic radiation therapy (FSRT) for brain metastases. We sought to evaluate the safety and efficacy of FSRT further define its role in metastasis management.A total 72 patients were treated with linear accelerator-based 182 previously untreated, intact Targets received 25 or 30 Gy 5 fractions. All targets within same course prescription regardless size. Toxicity was recorded per Radiation Therapy Oncology Group central nervous system toxicity...
We have investigated the dosimetric errors caused by interplay between motions of LINAC and tumor during delivery a volume modulated arc therapy treatment. This includes development an IMRT QA technique, applied here to evaluate RapidArc plans varying complexity.An technique was developed, which involves taking movie delivered dose (0.2 s frames) using 2D ion chamber array. Each frame is then moved according respiratory trace cumulative calculated. The advantage this approach that impact...
The purpose of this work is to examine physical radiation dose differences between two multileaf collimator (MLC) leaf widths (5 and 10 mm) in the treatment CNS head neck neoplasms with intensity modulated therapy (IMRT). Three clinical patients tumors were planned different MLC sizes, 5 mm, representing Varian‐120 Varian‐80 Millennium collimators, respectively. Two sets IMRT plans developed. goal first set was conformality three dimensions. for second organ avoidance a nearby critical...
Respiratory motion can introduce substantial dose errors during IMRT delivery. These are difficult to predict because of the nonsynchronous interplay between radiation beams and tissues. The present study investigates impact fractionation on respiratory induced dosimetric delivery their radiobiological implications by using measured 3D dose. We focused with dynamic multileaf collimation (DMLC‐IMRT). plans several beam arrangements were optimized for delivered a polystyrene phantom containing...
Flattening filter‐free (FFF) beams are available on an increasing number of commercial linear accelerators. FFF have higher dose rates than flattened equivalent energy which can lead to increased efficiency treatment delivery, especially in conjunction with beam and arc‐based delivery configurations. The purpose this study is quantify assess the implications improved for several options common types linac applicable radiotherapy. Eleven characteristic cases representative a variety clinical...
Developing automated methods to identify task-driven quality assurance (QA) procedures is key toward increasing safety, efficacy, and efficiency. We investigate the use of machine learning (ML) for possible visualization, automation, targeting QA, assess its performance using multi-institutional data.To enable analysis QA data given higher dimensional nature, we used nonlinear kernel mapping with support vector description (SVDD) driven approaches. Instead labeled as in typical (SVM)...
Abstract Purpose To evaluate the accuracy of monitoring intrafraction motion during stereotactic radiotherapy with optical surface system. Prior studies showing a false increase in magnitude translational offsets at non‐coplanar couch positions prompted vendor to implement software changes. This study evaluated two improvements intended address offsets. Methods The implemented improvements: volumetric (ACO) rather than planar calibration and, approximately 6 months later, an improved...
The clinical introduction of dedicated treatment units for online adaptive radiation therapy (OART) has led to widespread adoption daily radiotherapy. OART allows rapid generation plans using patient anatomy, potentially leading reduction margins and increased normal tissue sparing. However, the workflow does not allow measurement patient-specific quality assurance (PSQA) during delivery sessions instead relies on secondary dose calculations verification adapted plans. It remains unknown if...