A5003381572- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Radiation Dose and Imaging
- Radiation Therapy and Dosimetry
- Radiomics and Machine Learning in Medical Imaging
- Advances in Oncology and Radiotherapy
- Lung Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Breast Cancer Treatment Studies
- Digital Radiography and Breast Imaging
- Endometrial and Cervical Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Effects of Radiation Exposure
- Head and Neck Cancer Studies
- MRI in cancer diagnosis
- Cancer Genomics and Diagnostics
- Meningioma and schwannoma management
- Hematopoietic Stem Cell Transplantation
- Economic and Financial Impacts of Cancer
- Radiology practices and education
- Wireless Body Area Networks
- Hypertrophic osteoarthropathy and related conditions
- Electrical and Bioimpedance Tomography
- Facial Rejuvenation and Surgery Techniques
- Medical Imaging and Analysis
University of Alabama at Birmingham
2020-2025
The University of Texas Health Science Center at San Antonio
2013-2018
The University of Texas at San Antonio
2014-2016
University of California, San Francisco
2015
National Office of Mines
1990
Abstract Purpose Online Adaptive Radiation Therapy (oART) follows a different treatment paradigm than conventional radiotherapy, and because of this, the resources, implementation, workflows needed are unique. The purpose this report is to outline our institution's experience establishing, organizing, implementing an oART program using Ethos therapy system. Methods We include resources used, operational models utilized, creation timelines, institutional experiences with implementation...
Abstract Purpose Historically, the process of positioning a patient prior to imaging verification used set permanent marks, or tattoos, placed subcutaneously. After aligning these plan specific shifts are applied and position is verified with imaging, such as cone‐beam computed tomography ( CBCT ). Due variety factors, marks may deviate from desired it be hard align marks. Surface‐based systems an alternative method verifying initial entire skin surface instead tattoos. The aim this study...
To report adverse effects of high dose total body irradiation (TBI) delivered using a volumetric arc therapy (VMAT) technique and to assess pulmonary toxicity at rates 40 100 monitor units per minute (MU/min).
The clinical introduction of dedicated treatment units for online adaptive radiation therapy (OART) has led to widespread adoption daily radiotherapy. OART allows rapid generation plans using patient anatomy, potentially leading reduction margins and increased normal tissue sparing. However, the workflow does not allow measurement patient-specific quality assurance (PSQA) during delivery sessions instead relies on secondary dose calculations verification adapted plans. It remains unknown if...
Currently, there is insufficient guidance for standard fractionation lung planning using the Varian Ethos adaptive treatment system and its unique intelligent optimization engine. Here, we address this gap in knowledge by developing a methodology to automatically generate high-quality plans locally advanced cancer.
Abstract Purpose To report on the use of surface guided imaging during frameless intracranial stereotactic radiotherapy with automated delivery via HyperArc TM (Varian Medical Systems, Palo Alto, CA). Methods All patients received and were monitored for intrafraction motion by AlignRT® (VisionRT, London, UK) (SI) system. Immobilization was Encompass (Qfix, Avondale, PA) aquaplast mask device. log files correlated trajectory to correlate treatment parameters SI reported offsets. offsets...
To commission and assess the clinical performance of a new commercial surface imaging (SI) system by analyzing intra-fraction motion from initial cohort patients treated with frameless stereotactic radiosurgery (fSRS).
Abstract Purpose With the clinical implementation of kV‐CBCT‐based daily online‐adaptive radiotherapy, ability to monitor, quantify, and correct patient movement during adaptive sessions is paramount. lasting between 20–45 min, detect for small movements without restarting entire session critical workflow dosimetric outcome. The purpose this study was quantify evaluate correlation observed with machine logs a surface imaging (SI) system radiation therapy. Methods Treatment SGRT registration...
Abstract Purpose/objectives Recent technological advancements have increased efficiency for clinical deliverability of online‐adaptive‐radiotherapy (oART). Previous cone‐beam‐computed‐tomography (CBCT) generations lacked the ability to provide reliable Hounsfield‐units (HU), thus requiring oART workflows rely on synthetic‐CT (sCT) images derived through deformable‐image‐registration (DIR) between planning CT (pCT) and daily CBCT. These sCTs are prone errors stemming from DIR, potentially...
Background Accelerated partial breast irradiation (APBI) yields similar rates of recurrence and cosmetic outcomes as compared to whole radiation therapy (RT) when patients treatment techniques are appropriately selected. APBI combined with stereotactic body (SBRT) is a promising technique for precisely delivering high levels while avoiding uninvolved tissue. Here we investigate the feasibility automatically generating quality plans in Ethos adaptive workspace specific emphasis on sparing...
The use of deep learning to auto-contour organs at risk (OARs) in gynecologic radiation treatment is well established. Yet, there limited data investigating the prospective auto-contouring clinical practice. In this study, we assess accuracy and efficiency OARs for computed tomography-based brachytherapy planning malignancies.
Knowledge-based planning (KBP) offers the ability to predict dose-volume metrics based on information extracted from previous plans, reducing plan variability and improving quality. As clinical integration of KBP is increasing there a growing need for quantitative evaluation models. A .NET-based application, RapidCompare, was created automated creation analysis Varian RapidPlan models.RapidCompare designed read calculation parameters list reference plans. The tool copies field geometry...
Online adaptive radiotherapy (OART) is a promising technique for delivering stereotactic accelerated partial breast irradiation (APBI), as lumpectomy cavities vary in location and size between simulation treatment. However, OART resource-intensive, increasing planning treatment times decreasing machine throughput compared to the standard of care (SOC). Thus, it pertinent identify high-yield candidates best allocate resources.
Quality assurance (QA) of the image quality for image‐guided localization systems is crucial to ensure accurate visualization and regions interest within patient. In this study, temporal stability selected parameters was assessed evaluated kV CBCT mode, planar radiographic k V, MV modes. The motivation study better characterize variability in specific image‐quality parameters. CATPHAN, QckV‐1, QC‐3 phantoms were used evaluate imaging on a Varian Novalis Tx linear accelerator. images analyzed...
Purpose For stereotactic radiosurgery (SRS), accurate evaluation of dose‐volume metrics for small structures is necessary. The purpose this study was to compare the DVH metric capabilities five commercially available SRS analysis tools (Eclipse, Elements, Raystation, MIM, and Velocity). Methods DICOM RTdose RTstructure set files created using MATLAB were imported evaluated in each tools. Each structure consisted 50 randomly placed spherical targets. dose distributions on a 1‐mm grid an...
We compiled a sampling of the treatment techniques intensity-modulated total body irradiation, marrow irradiation and lymphoid utilized by several centers across North America Europe. This manuscript does not serve as consensus guideline, but rather is meant to convenient reference for that are considering starting an program.
New technologies are continuously emerging in radiation oncology. Inherent technological limitations can result health care disparities vulnerable patient populations. These must be considered for existing and new the clinic to provide equitable care.
Accelerated partial breast irradiation (APBI) is an attractive treatment modality for eligible patients as it has been shown to result in similar local control and improved cosmetic outcomes compared with whole radiation therapy. The use of online adaptive therapy (OART) APBI promising allows a reduction planning target volume margins because motion lumpectomy cavity changes are accounted daily imaging. Here we present retrospective, single-institution evaluation on the adequacy kV-cone beam...
Introduction:With the advent of complex treatment techniques like volumetric modulated arc therapy, there has been increasing interest in planning technologies aimed at reducing time. One these such is auto-planning, which an automated module within Pinnacle3. This study seeks to retrospectively evaluate dosimetric quality auto-planning-derived plans as they compare manual for intact prostate, prostate and lymph nodes, brain sites. Materials Methods:Previous clinical were used generate...