A5009467813- Synthesis and biological activity
- Fungal Plant Pathogen Control
- Synthesis and Biological Evaluation
- Asymmetric Synthesis and Catalysis
- Quinazolinone synthesis and applications
- Asymmetric Hydrogenation and Catalysis
- Synthetic Organic Chemistry Methods
- Lanthanide and Transition Metal Complexes
- Sulfur-Based Synthesis Techniques
- Chemical Synthesis and Analysis
- Synthesis and Catalytic Reactions
- Antibiotic Resistance in Bacteria
- Chemical Synthesis and Reactions
- Synthesis and Characterization of Heterocyclic Compounds
- Catalytic C–H Functionalization Methods
- Synthesis of heterocyclic compounds
- Synthesis and Reactions of Organic Compounds
- Multicomponent Synthesis of Heterocycles
- Antibiotic Use and Resistance
- Radioactive element chemistry and processing
- Axial and Atropisomeric Chirality Synthesis
- Advanced MRI Techniques and Applications
- Magnetism in coordination complexes
- MRI in cancer diagnosis
- Oxidative Organic Chemistry Reactions
Shandong Agricultural University
2013-2024
Xiamen University
2013-2023
Minzu University of China
2015-2017
Shanxi Agricultural University
2014-2016
State Ethnic Affairs Commission
2015
Sichuan University
2005-2013
Shuguang Hospital
2013
Shanghai University of Traditional Chinese Medicine
2013
174th hospital of the People's Liberation Army
2013
State Key Laboratory of Biotherapy
2011
The presence of organic micropollutants in water sources worldwide has created a need for the development effective and selective oxidation methods complex matrices. This study is first report combination ferrate(VI) (Fe(VI)) periodate (PI) synergistic, rapid, elimination multiple micropollutants. combined system was found to outperform other Fe(VI)/oxidant systems (e.g., H2O2, peroxydisulfate, peroxymonosulfate) rapid decontamination. Scavenging, probing, electron spin resonance experiments...
A chemo- and enantioselective [3 + 2] annulation of Morita–Baylis–Hillman carbonates isatins with propargyl sulfones was catalyzed by a β-ICD O-MOM ether 1c, affording spirocyclic 2-oxindoles bearing an unusual cyclopentadiene motif in outstanding ee values (up to >99%). More electrophiles, such as N-phenylmaleimide, have been also utilized deliver complex good results.
Six years have passed since renewed attention was paid to primary amines as potential organocatalysts in 2004. Numerous high quality studies this field provided chemists with valuable insights into the unique properties of chiral aminocatalysis. Among diverse catalysts, natural cinchona alkaloid-derived catalysts been widely regarded a branch efficiency. This review examines literature published between 2008 and late 2010, concerning amine catalysis.
Abstract Antimicrobial resistance (AMR) is a pressing issue in China, with antibiotic therapy becoming less effective against bacterial infections. To address this challenge, the China Surveillance Network (CHINET) was established 2005 to monitor antimicrobial country. This study analyzed CHINET data from teaching hospitals and evaluated trends of AMR 2018 2022. A range 163,636 301,917 isolates obtained per year, majority being Gram-negative bacilli (69.0% 71.8%). The proportion important...
The bifunctional thiourea–tertiary amine derivatives of simple chiral diamines serve as highly enantioselective catalysts for the Michael addition α-substituted cyanoacetates to vinyl sulfones, giving an efficient protocol construction all-carbon substituted quaternary stereocentre.
Abstract A Lewis base assisted Brønsted catalysis (LBABB) strategy is applied for direct asymmetric vinylogous alkylation of allylic sulfones with Morita–Baylis–Hillman (MBH) carbonates, in which a strong base, tert ‐butoxy anion, generated situ from tertiary amine catalyst and MBH carbonate, crucial activating unstabilized nucleophiles. The γ‐regioselective products were obtained good to excellent enantiomeric excess values when catalyzed by modified cinchona alkaloid.
Abstract BACKGROUND Botrytis cinerea is a serious plant fungus and strongly affects the yield quality of crops. The main control strategy employment fungicides. To research for efficient fungicide with novel structure, series benzimidazole derivatives bearing pyrimidine thioether moieties were designed synthesized. RESULTS Some target compounds such as 4h, 4i, 4k, 4l, 4m, 4s, 4t 4u exhibited notable fungicidal activities, half maximal effective concentration (EC 50 ) values in range...
Abstract Antimicrobial resistance poses a significant threat to global public health, especially for Enterobacterales. In this study, we investigated the distribution and antimicrobial of Enterobacterales in children China Surveillance Network (CHINET) 2015–2021. total, 81,681 strains isolated from were collected period, accounting 50.1% Gram-negative organisms. The most frequently Escherichia coli , Klebsiella spp., Salmonella Enterobacter spp. main sources isolates urine respiratory tract,...
Bifunctional chiral organocatalysts comprising thiourea and tertiary amine groups were synthesized. They act as efficient catalysts for asymmetric Michael addition of arylthiols to α,β-unsaturated carbonyl compounds. Enantioselectivity up 85% has been achieved. Asymmetric α-protonation reaction (up 60% ee) can be obtained in the presence bifunctional catalyst.
The aim of this paper is to examine the relationships among nurses' knowledge of, attitudes towards and level competence in nursing practice, as well factors influencing typhoon disaster relief work. A cross‐sectional descriptive study was conducted using a self‐developed questionnaire obtain data from 607 nurses working four tertiary hospitals two secondary F ujian, C hina, N ovember 2011. Our findings show that average percentage scores on their responses questions domains knowledge,...
The global prevalence and environmental risks of per- polyfluoroalkyl substances (PFASs) have caused increasing concern regarding their strategic elimination from aqueous environments. It has recently been recognized that advanced oxidation–reduction technologies (AO/RTs) exhibit superior removal performance for these ubiquitous pollutants. However, the detailed mechanisms product not well summarized systematically deciphered. In this mini-review article, basic operating principles two...
A series of novel N ‐(substituted phenyl/benzyl)‐2‐methylthio‐4‐((pyridin‐3‐ylmethyl)amino)pyrimidine‐5‐carboxamides were synthesized by multistep reactions. The structures the target compounds characterized IR, 1 H NMR, 13 C and elemental analysis. Their in vitro antifungal activities against two kinds plant pathogenic fungi evaluated mycelial growth rate method. result showed that at dosage 100 μg/mL, several these exhibited moderate activity Botrytis cinerea with inhibition rates ~70%,...
An efficient and catalyst-free synthesis of trisubstituted allylic sulfones through an sulfonylation reaction Morita-Baylis-Hillman (MBH) carbonates with sodium sulfinates has been developed. Under the optimized conditions, a series were rapidly prepared in good to excellent yields (71%–99%) high selectivity (Z/E from 79:21 >99:1). Compared known synthetic methods, current protocol features mild temperature, efficiency easily available reagents.
Point mutation G143A in the cytochrome b (Cyt b) protein commonly confers resistance to quinone outside inhibitor (QoI) fungicides phytopathogenic fungi, including Corynespora cassiicola, which causes cucumber target spot disease. However, effect of on binding between QoI fungicide and Cyt protein, use LAMP (loop-mediated isothermal amplification) detect this point had not been reported previously C. cassiicola. In study, sensitivity 131 cassiicola isolates—collected from Shandong province,...
Abstract A direct, asymmetric allylic alkylation of indenes withMorita–Baylis–Hillman (MBH) carbonates has been developed based on a Lewis base assisted Brønsted catalysis strategy. This process is promoted by modified cinchona alkaloid hydroquinidine (anthraquinone‐1,4‐diyl) diether [(DHQD) 2 AQN] and gives rise to multifunctional chiral indene derivatives with moderate excellent enantioselectivities (53–95 % ee ), albeit in low modest yields (27–71 %).
A series of novel pyrimidine derivatives with (pyridin-3-ylmethyl)thio and phenylamino moieties were synthesized from ethyl acetoacetate, thiourea, 3-pyridinylmethyl chloride hydrochloride, substituted anilines by multi-step reactions. The structures the target compounds characterized IR, 1H NMR, 13C NMR elemental analysis. in vitro antifungal activities against Botrytis cinerea Sclerotinia sclerotiorum evaluated. result showed that N-phenyl-6-methyl-2- ((pyridin-3-ylmethyl)thio)...
Abstract Thermal property of soy protein isolates (SPI) was studied with differential scanning calorimetry and thermogravimetric analysis. The weight loss pure SPI is about 300°C. glass transition temperature ( T g ) above 200°C. best molding glycerin plasticized plastics were then given. It between 125 140°C. Subsequently the special molded investigated. Results show that atmosphere humidity affects mechanical thermal plastics. With increasing humidity, tensile strength decreases. While...