A5028663989- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Systemic Sclerosis and Related Diseases
- Pulmonary Hypertension Research and Treatments
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- Asthma and respiratory diseases
- Inflammatory Biomarkers in Disease Prognosis
- Family and Patient Care in Intensive Care Units
- COVID-19 and healthcare impacts
- Nosocomial Infections in ICU
- Neonatal Respiratory Health Research
- Pleural and Pulmonary Diseases
- Pneumothorax, Barotrauma, Emphysema
- Electrolyte and hormonal disorders
- Mechanical Circulatory Support Devices
- Tuberculosis Research and Epidemiology
- Lung Cancer Diagnosis and Treatment
- Infectious Diseases and Tuberculosis
- Respiratory and Cough-Related Research
- SARS-CoV-2 and COVID-19 Research
Marmara University
2016-2025
Ondokuz Mayıs University
2025
Marmara Üniversitesi Eğitim ve Araştırma Hastanesi
2015-2021
Afyon Kocatepe University
2018
Karadeniz Technical University
2013-2018
Adıyaman University
2018
Amerikan Hastanesi
2018
Sakarya University
2018
Izmir University
2018
Dokuz Eylül University
2018
In order to investigate the role of bacteria, including Mycoplasma pneumoniae and especially Chlamydia in acute purulent exacerbations chronic obstructive pulmonary disease (COPD), we examined sputum specimens convalescent sera taken 26 d apart from 49 outpatients experiencing an exacerbation COPD. The were tested for antibodies C. with microimmunofluorescence test, M. indirect fluorescence antibody test. Routine microbiologic culture yielded potentially pathogenic microorganisms 12 patients...
Right ventricular dysfunction and N-terminal proB-type natriuretic peptide (NT-proBNP) are established determinants of prognosis in acute pulmonary embolism (PE). The aim the study was to investigate prognostic value C-reactive protein (CRP) PE.Fifty-six patients (mean age, 64.4 T 14.8years; 22 male subjects) with PE were consecutively enrolled followed for 36 months after discharge. Serum CRP, NT-proBNP, troponin levels determined. function evaluated by transthoracic echocardiography.Right...
This prospective observational study describes the pharmacokinetic characteristics of favipiravir in adult patients hospitalized for mild to moderate COVID‐19 with a positive RT‐PCR test. Favipiravir was administered 5 days, loading dose 3200 mg and maintenance 1200 mg/day. Serial blood samples were collected on Day 2 4 therapy. Laboratory findings ( n = 21) in‐hospital mortality recorded. concentrations exhibited substantial variability significant decrease during treatment COVID‐19. The...
Despite the known systemic manifestations of inflammatory bowel disease (IBD) and a large number reports associating lung IBD, frequency atopy bronchial hyperreactivity (BHR) in IBD remains obscure.The aim this study was to investigate prevalence abnormal pulmonary function tests, BHR atopic status patients with IBD.Thirty (19 ulcerative colitis 11 Crohn's disease; 19 male, female) 16 controls without any gastrointestinal (9 female, 7 male) were included. Patients questioned respect allergic...
Pulmonary endarterectomy (PEA) is the treatment of choice for patients with chronic thrombo-embolic pulmonary hypertension (CTEPH). The aim this study was to review our initial experience since implementation program. Data were collected prospectively on all who underwent PEA between March 2011 and 2012. Forty-nine (20 male, 29 female, mean age 47.7 years) surgery. preoperative New York Heart Association class distribution showed majority be in III or IV (n = 40). Mortality rate 14.2% 7)...
<h3>BACKGROUND:</h3> Ultrasound-based diaphragmatic thickness fraction is a reflection of the size and function diaphragm. This study aimed to examine value this measurement in identifying patients with COPD who are at high risk for development symptoms exacerbations. <h3>METHODS:</h3> cross-sectional included 53 subjects COPD. Respiratory test results, ultrasonography-based thickness, symptom scores (modified Medical Research Council dyspnea scale); Assessment Test number previous...
Background Antimicrobial use in ICUs is challenging due to altered pharmacokinetics, severe infections, and the burden of comorbidities. This study aims investigate contribution clinical pharmacy services reducing antimicrobial drug therapy problems (ADTPs) intensive care unit. Methods was a prospective, pre-post intervention conducted over total duration 6 months (15 January 2023–15 July 2023) Türkiye. During both control period (CP) (IP), ADTPs were identified classified according...
Objective. To compare the Quantiferon-TB Gold test (QTF-G) with tuberculin skin (TST) for detection of latent tuberculosis infection (LTBI) among patients rheumatoid arthritis (RA) and ankylosing spondylitis (AS), reevaluation treated tumor necrosis factor-α (TNF-α) antagonists in followup. Methods. The study involved 140 consecutive patients, 82 RA 58 AS. Thirty were evaluated QTF-G LTBI before after 6 months TNF-α antagonist treatment. was also performed on 49 healthy controls. results...
Background: Pulmonary embolism (PE) poses significant morbidity and mortality risks, necessitating tailored anticoagulant therapy. Limited studies investigate the drug-related problems (DRPs) in PE. This study aims to evaluate impact of clinical pharmacist (CP) interventions on outcomes outpatients with By addressing DRPs this specific population, seeks assess role CP-led enhancing patient safety optimizing treatment outcomes. Methods: A randomized controlled trial was conducted PE patients...
Effective postoperative pain management is crucial in caesarean delivery (CD) to enhance recovery, minimize opioid use, and improve maternal outcomes. Intrathecal morphine (ITM) widely used but can cause side effects, such as pruritus nausea. Posterior quadratus lumborum block (QLB) has emerged a potential alternative for analgesia. This study compared the analgesic efficacy side-effect profiles of ITM posterior QLB patients with CD. prospective observational included parturients who...
Abstract Background Tumor necrosis factor‐alpha ( TNF ‐ α ) antagonist treatment is associated with 1.6 to 27 times higher risk of tuberculosis TB ). Objective To find incidence psoriasis patients treated antagonists and define factors related this condition in a country moderately high . Methods Three hundred seventy by anti‐ agents four referral centers were included. The data on the characteristics patients, history, skin test results, agent type exposure time, localization , isoniazide...
To assess the effect of mycophenolate mofetil (MMF) on pulmonary functions in patients with systemic sclerosis-associated lung disease (SSc-ILD) who experienced an inadequate response to first line cyclophosphamide (CYC) therapy. Twelve consecutive SSc-ILD received MMF due CYC as a agent, were retrospectively reviewed. Over course 2 years, function tests (PFT) and high-resolution computed tomography (HRCT) scans performed. Following initial baseline tests, PFTs continued at frequency every 6...
Objective: Thickness of the diaphragm was evaluated by B-mode ultrasonography (US) in chronic obstructive pulmonary disease (COPD) to determine relationship between thickness measurement, function tests, and symptom scores.Patients Methods: Fifty-three clinically stable patients with COPD were enrolled this study for diaphragmatic evaluation US.The severity determined spirometric measurements terms %FEV1.Patients also analyzed according GOLD criteria.Correlation scores like Medical Research...
Introduction As of December 2019, the COVID-19 infection had spread rapidly across globe, causing a pandemic. Although virus primarily affects respiratory and circulatory systems, neuropsychiatric disorders have been reported in significant number infected individuals. The aim this study is to identify anxiety, depression, sleep disturbances early post-COVID period, as well potential risk factors. Method Symptomatic cases whose diagnosis was confirmed by polymerase chain reaction (PCR)...
Background: Alterations in the neuroendocrine system occur during critical illness. Chronic obstructive pulmonary disease (COPD) itself causes hormonal changes. The aim of this study was to determine neu roendocrine hormones COPD patients with acute respiratory failure and investigate relationship between changes, mortality, morbidity.Methods: We enrolled 21 (13 F/8 M) exacerbation requiring artificial airway support. Blood samples were collected on admission ICU, day hospital discharge....
The tuberculin skin test (TST) has low sensitivity for the diagnosis of tuberculosis (TB). QuantiFERON-TB Gold (QFT-G) is an IFN-gamma-release assay that measures release interferon-gamma after stimulation in vitro by Mycobacterium antigens using ELISA. main advantage this compared with TST lack cross-reaction Bacillus Calmette-Guérin (BCG) as well most non-tuberculous mycobacteria. aim our study to compare QFT-G detection latent infection (LTBI) among patients systemic lupus erythematosus...
Comparison of neutrophil to lymphocyte ratio with other prognostic markers affecting 30 day mortality in acute pulmonary embolismIntroduction: Identifying the factors for patients embolism (APE) play a critical role determining treatment strategy and reduce mortality.The aim this study is evaluate value Neutrophil Lymphocyte Ratio (NLR) compare NLR APE. Materials Methods: We retrospectively examined 550 cases diagnosed by spiral computed tomographic angiography.A receiver operating...
<h3>BACKGROUND:</h3> Definite diagnosis of transudative or exudative pleural fluids often presents a diagnostic dilemma. The aim this study was to evaluate whether amino-terminal brain natriuretic peptide (NT-proBNP) levels in fluid has value for discriminating heart-failure-related effusions from non-heart-failure effusions. <h3>METHODS:</h3> Sixty-six subjects (40 male, mean age 61 ± 18 y) with were included. Samples and serum obtained simultaneously each subject. Biochemical analysis,...
Inadequate adaptation to long-term treatment of chronic illnesses is the most common reason for inability obtain benefits medications can provide. Treatment compliance influenced by several factors. Beliefs about Medicines Questionnaire (BMQ) developed Horne et al. in 1999 evaluate cognitive representation medicines have many validation studies, which resulted good psychometric properties. The aim present study was reliability and validity BMQ Turkish translation patients with asthma...
Lactate dehydrogenase (LDH) levels predict coronavirus disease 2019 (COVID-19) severity. We investigated LDH isoenzyme to identify the tissue responsible for serum elevation in patients with COVID-19.Hospitalised COVID-19 exceeding upper reference limit included. isoenzymes were detected quantitatively on agarose gels. The radiological severity of lung involvement computed tomography was scored as 0-5 each lobe (total possible score, 0-25). Disease determined using World Health Organization...