A5065545768- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac pacing and defibrillation studies
- Streptococcal Infections and Treatments
- Abdominal vascular conditions and treatments
- Cardiac Arrest and Resuscitation
- Antimicrobial Resistance in Staphylococcus
- Cardiac tumors and thrombi
- Antiplatelet Therapy and Cardiovascular Diseases
- Infectious Aortic and Vascular Conditions
- Mechanical Circulatory Support Devices
- Cardiac Arrhythmias and Treatments
- Omental and Epiploic Conditions
- Pectus Deformity Diagnosis and Treatment
- S100 Proteins and Annexins
- Cardiovascular Syncope and Autonomic Disorders
- Pericarditis and Cardiac Tamponade
- Body Contouring and Surgery
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Abdominal Surgery and Complications
- Atrial Fibrillation Management and Outcomes
Technische Universität Dresden
2022-2025
University Hospital Carl Gustav Carus
2023-2024
Deutsches Herzzentrum der Charité
2023
University Hospital in Halle
2013-2018
Cancer Clinic
2018
Martin Luther University Halle-Wittenberg
2016
Background and Objectives: Transaxillary access is one of the latest innovations for minimally invasive aortic valve replacement (MICS-AVR). This study compares clinical performance in a large transaxillary MICS-AVR group to propensity-matched sternotomy control group. Materials Methods: enrolled 908 patients undergoing isolated AVR with mean age 69.4 ± 18.0 years, logistic EuroSCORE 4.0 3.9%, body mass index (BMI) 27.3 6.1 kg/m2. The treatment comprised 454 consecutive patients. was 1:1 out...
In an older population, infective endocarditis tends to present uniquely. this study we investigate the clinical presentation, microbiological profile and outcomes of in octogenarians. This multicenter retrospective analysis includes 4917 consecutive patients suffering from endocarditis. We analysed data on octogenarians undergoing surgery due Primary were 30-day mortality 5-year survival. found 4625 (94.1%) younger than 80 years old, whereas 292 (5.9%) The median age non-octogenarian cohort...
Background: In cardiac surgery, protamine is used to reverse the effects of heparin after separation from cardiopulmonary bypass (CPB). Excess has been demonstrated cause platelet dysfunction and coagulopathy. A protamin-to-heparin ratio less than 1:1 endorsed by European guidelines. Pharmacokinetic models decay have proposed allow for individualised dosing rather fixed ratios. The objective this study compare three such in a large cohort simulated patients. Methods: doses were calculated...
(1) Background: Right anterior thoracotomy (RAT-AVR) has been the sole established sternum-sparing technique for minimally invasive aortic valve replacement (MICS-AVR) thus far. Nevertheless, transaxillary access, known as Minimally Invasive Cardiac LATeral Surgery (MICLATS-AVR), represents latest and innovative advancement in MICS-AVR access routes. In this study, procedural clinical outcomes of a substantial cohort are compared to those RAT-AVR control group; (2) Patients Methods: This...
Sex-related differences play a role in cardiovascular disease-related outcomes. There is, however, knowledge gap regarding sex-specific patients with infective endocarditis (IE)-requiring surgical treatment. This study aims to analyse sex-related the clinical presentation, treatment and outcomes of IE-requiring from multicentric Germany-wide CAMPAIGN registry.
(1) Background: this study addresses the lack of comprehensive research on outcomes in octogenarians undergoing cardiac surgery for multivalvular disease, emphasizing need a critical examination intervention’s overall worth aging population. (2) Methods: By analyzing short-term and mid-term data from 101 consecutive octogenarian patients multivalve surgery, identifies predictors in-hospital one-year mortality. (3) Results: In-hospital mortality increased fourfold with occurrence at least one...
Abstract OBJECTIVES This study aimed to analyse the impact of preoperative septic cerebral embolism on early and late postoperative outcomes in patients with infective endocarditis undergoing valve surgery. METHODS Retrospective multicentric based Clinical Multicentric Project for Analysis Infective Endocarditis Germany (CAMPAIGN) registry comprising who underwent surgery between 1994 2018 at 6 German centres. Patients were divided into 2 groups statistical comparison according presence or...
Background: Aortic valve infective endocarditis (AV-IE) and mitral (MV-IE) are often grouped together as one entity: left-sided endocarditis. However, there significant differences between the valves in terms of anatomy, physiology, pressure, calcification tendency. This study aimed to compare AV-IE MV-IE patient characteristics, pathogen profiles, postoperative outcomes, predictors mortality. Methods: We retrospectively analyzed data from 3899 patients operated on for isolated or six German...
The transaxillary concept for minimally invasive cardiac surgery-aortic valve replacement is a new and versatile approach with nearly no visible scars. Due to its novelty, available data in literature are scarce. This study reports clinical outcomes of 1000 consecutive patients.
Interstitial 5q22 deletions are relatively rare and usually represented by severe clinical features such as developmental delay growth retardation. Here, we report a 23-year-old male patient, referred to our laboratory for genetic confirmation of possible familial adenomatous polyposis. MLPA the subsequent array CGH identified an approximately 8-Mb-sized deletion in 5q22.2q23.1 locus. Further analysis deleted region genes within suggested role TSSK1B (testis-specific serine/threonine kinase...
Background and Objectives: Transaxillary access is a straightforward “single incision—direct vision” concept, based on 5 cm skin incision in the right anterior axillary line. It suitable for aortic, mitral tricuspid surgery. The present study evaluates hospital outcomes of transaxillary isolated valve surgery compared with full sternotomy. Patients Methods: final group included 480 patients. A total 160 consecutive patients served as treatment (MICS-MITRAL). Based multivariate logistic...
(1) Background and Objectives: Transcatheter aortic valve implantation is guideline-recommended from the age of 75. However, this European guideline recommendation based on limited evidence, since no interaction between primary outcome has been found in guideline-stated references. This study aimed to compare short-term outcomes minimally invasive isolated replacement patients aged ≥ 75 with those younger patients; (2) Patients Methods: retrospective cohort included 1339 who underwent at our...
Background: Redo mitral valve surgery is the standard of care for failed bioprostheses or recurrence regurgitation after repair. Nonetheless, catheterbased valve-in-valve (ViV) valve-in-ring (ViR)-procedures increasingly become viable alternatives in high risk subpopula-tions. Despite reported good initial results, only little known about longer-term outcomes. The present series report long-term outcomes transcatheter ViV- and ViR-procedures. Methods: All consecutive patients (n=54)...
Redo mitral valve surgery is the standard of care for failed bioprostheses or recurrence regurgitation after repair. Nonetheless, catheter-based valve-in-valve (ViV) valve-in-ring (ViR) procedures have increasingly become viable alternatives in high-risk subpopulations. Despite reported good initial results, little known about longer-term outcomes. Here, we report long-term outcomes transcatheter ViV and ViR procedures. All consecutive patients (n = 54) undergoing recurring repair time...
Abstract Background Postprocedural thrombocytopenia is a known phenomenon following transcatheter aortic valve implantation (TAVI). The aim of this study to evaluate whether postinterventional platelet kinetics differ when comparing the current generation balloon-expandable (BEV) and self-expanding (SEV) prostheses. Methods We performed retrospective analysis patients undergoing TAVI at our facility between 2017 2019. Patients were stratified according type prosthesis used: BEV or SEV....
Background: Mesenteric ischemia (Me-Is) after cardiac surgery is underreported in present literature. Despite scarce scientific data, Me-Is has the bad reputation of a dismal prognosis. This study adds clinical outcomes large patient cohort.
Background: Until now, minimally invasive cardiac surgery (MICS) failed to demonstrate survival benefits in a general population—assumably due selection bias effects. With this series we evaluate the outcomes of MICS adipose patients compared with propensity-matched sternotomy cohort.