A5017432845- Infective Endocarditis Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Streptococcal Infections and Treatments
- Congenital Heart Disease Studies
- Infectious Aortic and Vascular Conditions
- Bacterial Identification and Susceptibility Testing
- Cardiac Health and Mental Health
- Healthcare during COVID-19 Pandemic
- Orthopedic Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- Cardiac Ischemia and Reperfusion
- Cardiac, Anesthesia and Surgical Outcomes
- Organ Transplantation Techniques and Outcomes
- Cardiac pacing and defibrillation studies
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Reconstructive Surgery and Microvascular Techniques
Leipzig Heart Institute
2023-2025
Deutsches Herzzentrum der Charité
2024-2025
Leipzig University
2024
Sex-related differences play a role in cardiovascular disease-related outcomes. There is, however, knowledge gap regarding sex-specific patients with infective endocarditis (IE)-requiring surgical treatment. This study aims to analyse sex-related the clinical presentation, treatment and outcomes of IE-requiring from multicentric Germany-wide CAMPAIGN registry.
Background: The survival advantages of bilateral internal thoracic artery (BITA) grafts in coronary bypass surgery (CABG) remain unclear. Therefore, this study aims to systematically evaluate the time-dependent influence BITA on long-term elective CABG patients presenting with stable multi-vessel disease. Methods: Data from 3,693 undergoing isolated single (SITA) or BITA, without additional vein grafts, between 2002 and 2012 were retrospectively analyzed. entire cohort was divided into SITA...
The Heart Center Leipzig has implemented an innovative off-pump minimally invasive cardiac surgery-coronary artery bypass grafting approach, focusing on complete arterial revascularization using bilateral mammary arteries through a incision (left anterolateral minithoracotomy). This technique been successfully incorporated into routine clinical practice at our centre for the past 8 years. majority of patients are eligible this procedure. video tutorial provides overview patient selection,...
Abstract OBJECTIVES This review article aims to examine the surgical approach patients with failed mitral transcatheter edge-to-edge repair (M-TEER), focusing on operative challenges, decision-making, and contemporary outcome data. Technical considerations, including device removal management of complex valve (MV) anatomy is discussed. METHODS We performed a comprehensive literature gathered experience from high-volume centers in M-TEER. RESULTS MV surgery after M-TEER but increasingly...
Abstract OBJECTIVES This study aimed to analyse the impact of preoperative septic cerebral embolism on early and late postoperative outcomes in patients with infective endocarditis undergoing valve surgery. METHODS Retrospective multicentric based Clinical Multicentric Project for Analysis Infective Endocarditis Germany (CAMPAIGN) registry comprising who underwent surgery between 1994 2018 at 6 German centres. Patients were divided into 2 groups statistical comparison according presence or...
Perivalvular abscesses with destruction of the aortomitral junction (AMJ) are a severe complication infective endocarditis (IE) and associated high mortality complex management. The Hemi-Commando procedure is mitral valve-sparing alternative to Commando in suitable patients IE paravalvular destruction. This study reviews mid-term outcomes undergoing for treating AMJ.The clinical AMJ involvement who underwent between 2015 2021 at Leipzig Heart Center were retrospectively analysed. Primary...
Comparative studies of outcomes between different biological mitral valve prostheses are scarce. This study compares the late clinical results replacement with Epic and Mosaic bioprostheses. Patients undergoing isolated elective (MVR) 2005 2019 were eligible for inclusion. Primary freedom from reintervention overall survival. Inverse probability treatment weighting competing risk analyses performed. MVR was performed in 247 (73.7%) patients prosthesis 88 (26.3%) prosthesis. The median...
Background: Intestinal bacterial translocation due to right ventricular dysfunction and subsequent portal venous hypertension is a proposed mechanism for the increased incidence of systemic inflammatory response syndrome vasoplegia following tricuspid valve (TV) surgery. We hypothesize that using preoperative intestinal preconditioning protocol composed an oral antibiotic (Rifaximin) laxatives 24 hours before surgery can help reduce translocation, thus reducing postoperative vasoplegia. This...
Abstract OBJECTIVES The frequency of minimally invasive mitral valve surgery (MVS) has steadily increased over the last decades and therefore surgeons are now encountering an increasing number patients requiring (MV) reoperations post-minimally MVS. aim this study was to analyse early postoperative outcomes long-term survival in who undergo reoperative MVS following previous surgery. METHODS Patients underwent redo prior between January 2002 December 2021 were included our analysis. Study...
Although mitral valve repair is the preferred surgical strategy in children with disease, there are cases of irreparable severe dysplastic valves that require replacement. The aim this study to analyze long-term outcomes following replacement a tertiary referral center.
ObjectiveThis study compares early and long-term outcomes following mitral valve (MV) repair replacement in patients with regurgitation (MR) reduced left ventricular ejection fraction (LVEF).MethodsPatients primary or secondary MR LVEF <50% who underwent MV (with/without atrial septal defect closure and/or fibrillation ablation) between 2005 2017 at our center were retrospectively analyzed using unadjusted propensity score matching techniques (42 pairs).ResultsA total of 356 either (n = 162...
<title>Abstract</title> Background Aortic coarctation accounts for 5–8% of congenital heart defects and patients’ symptoms can present from neonatal shock to hypertension in adolescence or even adulthood. While surgical repair is the gold standard, catheter-based therapies are increasingly utilized. Despite advancements, complications recurrence rates necessitating re-intervention remain concerns. Methods We analyzed postoperative outcomes long-term intervention pediatric patients undergoing...
Abstract OBJECTIVES The study aimed to review a multicentre experience of patients undergoing surgical intervention for infective endocarditis caused by Cutibacterium acnes and analyse the diagnostic challenges operative results. METHODS We retrospectively reviewed 8812 cardiac surgery at 12 departments across Germany. overall population was divided based on type (i.e. native prosthetic valve endocarditis). Primary outcomes were in-hospital mortality, 1- 5-year survival. RESULTS in 269...
Introducción: La arteria mamaria interna es el único injerto con impacto a largo plazo en la mortalidad de los pacientes enfermedad coronaria. Existen interrogantes que limitan uso simultáneo ambas arterias, como tiempo quirúrgico prolongado y riesgo infecciones esternales especialmente diabéticos obesos. Este estudio buscó describir comportamiento 5 años revascularizados bilateral (BIMA). Métodos: Estudio descriptivo seguimiento una cohorte. 42 sometidos revascularización miocárdica BIMA...
Introduction: The internal mammary artery is the only graft with a long-term impact on mortality in patients coronary disease. Some questions limit use of both arteries simultaneously, such as prolonged surgical time, risk sternal infections, especially diabetic and obese patients. This study sought to describe 5-year experience revascularized bilateral (BIMA). Methods: Descriptive cohort follow-up study. 42 underwent myocardial revascularization BIMA between 2015-2020, Manuel-Uribe-Ángel...