Shekhar Saha
A5087307232- Infective Endocarditis Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Antimicrobial Resistance in Staphylococcus
- Cardiac, Anesthesia and Surgical Outcomes
- Streptococcal Infections and Treatments
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Intensive Care Unit Cognitive Disorders
- Cardiac Imaging and Diagnostics
- Anesthesia and Neurotoxicity Research
- Respiratory Support and Mechanisms
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Function and Risk Factors
- Infectious Aortic and Vascular Conditions
- Orthopedic Infections and Treatments
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Coronary Interventions and Diagnostics
- Infectious Diseases and Tuberculosis
- Cardiac Structural Anomalies and Repair
- Peripheral Artery Disease Management
- Pulmonary Hypertension Research and Treatments
- Pleural and Pulmonary Diseases
- Aortic aneurysm repair treatments
- Reconstructive Facial Surgery Techniques
Ludwig-Maximilians-Universität München
2019-2025
German Centre for Cardiovascular Research
2022-2025
Mahatma Gandhi Institute of Medical Sciences
2025
LMU Klinikum
2021-2024
University of Göttingen
2018-2022
University Hospital Magdeburg
2019
Otto-von-Guericke University Magdeburg
2017-2019
University Medical Center
2018
Leipzig University
2017
Abstract Background and Aims Surgical explantation of transcatheter heart valves (THVs) is rapidly increasing, but there are limited data on patients with THV-associated infective endocarditis (IE). This study aims to assess the outcomes undergoing THV explant for IE. Methods All who underwent between 2011 2022 from 44 sites in EXPLANT-TAVR registry were identified. Patients IE as reason compared those other mechanisms bioprosthetic valve dysfunction (BVD). Results A total 372 included....
In an older population, infective endocarditis tends to present uniquely. this study we investigate the clinical presentation, microbiological profile and outcomes of in octogenarians. This multicenter retrospective analysis includes 4917 consecutive patients suffering from endocarditis. We analysed data on octogenarians undergoing surgery due Primary were 30-day mortality 5-year survival. found 4625 (94.1%) younger than 80 years old, whereas 292 (5.9%) The median age non-octogenarian cohort...
Sex-related differences play a role in cardiovascular disease-related outcomes. There is, however, knowledge gap regarding sex-specific patients with infective endocarditis (IE)-requiring surgical treatment. This study aims to analyse sex-related the clinical presentation, treatment and outcomes of IE-requiring from multicentric Germany-wide CAMPAIGN registry.
Multi-organ failure is one of the leading causes mortality after cardiac surgery for infective endocarditis (IE). Although randomized evidence does not support use hemoadsorption during IE, observational studies suggest a beneficial effect in selected patient groups. We aimed to analyze sex differences on patients with IE. This post-hoc analysis REMOVE-trial that IE who underwent using CytoSorb® or control. The primary endpoint was variation Sequential Organ Failure Assessment (ΔSOFA),...
Abstract OBJECTIVES With the expansion of transcatheter aortic valve replacement (TAVR) into intermediate and low risk, number TAVR procedures is bound to rise along with it cases infective endocarditis following (TIE). The aim this study was review a multicentre experience patients undergoing surgical intervention for TIE analyse underlying indications operative results. METHODS We retrospectively identified analysed 69 who underwent cardiac surgery due at 9 departments across Germany....
Background: This retrospective multicenter study investigates the impact of obesity on short-term surgical outcomes in patients with heart failure and reduced ejection fraction (HFrEF) undergoing coronary artery bypass grafting (CABG). Given rising global prevalence its known cardiovascular implications, understanding specific effects high-risk groups like HFrEF is crucial. Methods: The analyzed data from 574 CABG across four German university hospitals 2017 to 2023. Patients were stratified...
Minimally invasive mitral valve surgery (MIMVS) through an endoscopic right minithoracotomy is a well-established yet complex procedure that has challenging learning curve. We have developed simulator for MIMVS and evaluated its short- long-term training effects.Trainees without experience or in were divided into 2 groups (10 students 10 residents) participated 5-day course after initial instruction. Each trainee performed ring annuloplasty. Scores given by supervisor who assessed 5 skills....
This study aimed to compare postoperative outcomes and 30-day mortality in patients with reduced ejection fraction (<40%) who underwent isolated coronary artery bypass grafting (CABG) (ONCAB) without (OPCAB) the use of cardiopulmonary bypass.data from four university hospitals Germany, spanning January 2017 December 2021, were retrospectively analyzed. A total 551 included study, various demographic, intraoperative, data compared.demographic parameters did not exhibit any differences....
Objectives: As surgical experience with infective endocarditis following transcatheter aortic valve replacement is scarce, this study compared the perioperative and short-term outcomes of patients suffering from replacement. Methods: Between January 2013 December 2020, 468 consecutive were admitted to our center for surgery IE. Among them, 98 operated on 22 Results: The median EuroSCORE II (52.1 (40.6-62.0) v/s 45.4 (32.6-58.1), p = 0.207) STS-PROM (1.8 (1.6-2.1) 1.9 (1.4-2.2), 0.622)...
Objective: Infective endocarditis (IE) caused by Staphylococcus species (spp.) is believed to be associated with higher morbidity and mortality rates. We hypothesize that spp. are more virulent compared other commonly causative bacteria of IE regard short-term long-term mortality. Background: It remains unclear if patients suffering from due should referred for surgical treatment earlier than avoid septic embolism optimize perioperative outcomes. Materials Methods: The database the CAMPAIGN...
Objectives: Minimally invasive extracorporeal circulation circuits provide several advantages compared to conventional circuits. We the results of a minimally system with those system, in patients undergoing isolated coronary artery bypass grafting. Methods: identified 753 consecutive who underwent grafting at our centre between October 2014 and September 2016. These were divided into two groups: group (M, n = 229) (C, 524). Baseline parameters, details cardiac surgery as well postoperative...
To analyze Heart Team decisions and outcomes following failure of surgical aortic valve replacement (SAVR) prostheses.