Luca Fazzini

ORCID: 0000-0003-2407-7435
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About
Contact & Profiles
Research Areas
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Effects of Exercise
  • Heart Failure Treatment and Management
  • Cardiac Valve Diseases and Treatments
  • Cardiac pacing and defibrillation studies
  • Cardiomyopathy and Myosin Studies
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Viral Infections and Immunology Research
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular and exercise physiology
  • Cardiac electrophysiology and arrhythmias
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Lung Cancer Diagnosis and Treatment
  • Pleural and Pulmonary Diseases
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac Arrhythmias and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Management of metastatic bone disease
  • Acute Myocardial Infarction Research
  • Mechanical Circulatory Support Devices
  • Cardiovascular Syncope and Autonomic Disorders
  • Eosinophilic Disorders and Syndromes
  • PARP inhibition in cancer therapy
  • Amyotrophic Lateral Sclerosis Research
  • Amyloidosis: Diagnosis, Treatment, Outcomes

University of Cagliari
2021-2025

Mayo Clinic
2024-2025

WinnMed
2025

Mayo Clinic in Arizona
2024

Heart failure (HF) is a significant disease affecting 1–2% of the general population. Despite its aspects, HF, like other cardiovascular diseases, presents various gender-specific aspects in terms etiology, hemodynamics, clinical characteristics, therapy, and outcomes. As well known, HF with preserved ejection fraction more frequently affects females, diabetes arterial hypertension representing most critical determinants HF. On hand, women are traditionally underrepresented trials often...

10.3390/jcm13030881 article EN Journal of Clinical Medicine 2024-02-02

Abstract Aims The identification of subjects at higher risk for incident heart failure (HF) with preserved ejection fraction (EF) suitable more intensive preventive programmes remains challenging. We applied phenomapping to the DAVID‐Berg population, comprising preclinical HF, aiming refine HF stratification. Methods study prospectively enrolled 596 asymptomatic outpatients EF > 40% hypertension, diabetes mellitus or known cardiovascular disease. In this cohort, we performed an...

10.1002/ehf2.14913 article EN cc-by-nc ESC Heart Failure 2024-07-04

Abstract Background Left ventricular (LV) ventricular-arterial coupling (VAC) refers to the ratio of afterload (effective arterial elastance) contractility (end-systolic as an integrated marker cardiac performance. We sought determine whether echocardiographic VAC ratio, defined using LV end-systolic volume (LVESV) stroke (SV), predicted mortality in intensive care unit (CICU). Methods Mayo Clinic CICU patients from 2007 and 2018 were included. was calculated Teichholz LVESV divided by SV...

10.1093/ehjacc/zuaf038 article EN European Heart Journal Acute Cardiovascular Care 2025-03-12

Multi-organ failure is one of the leading causes mortality after cardiac surgery for infective endocarditis (IE). Although randomized evidence does not support use hemoadsorption during IE, observational studies suggest a beneficial effect in selected patient groups. We aimed to analyze sex differences on patients with IE. This post-hoc analysis REMOVE-trial that IE who underwent using CytoSorb® or control. The primary endpoint was variation Sequential Organ Failure Assessment (ΔSOFA),...

10.1016/j.ijcard.2025.133371 article EN cc-by International Journal of Cardiology 2025-05-01

Numerous studies underscore the benefits of exercise prescription in both cardiology and oncology. Recently, emerging eviAlessandro Navadence has highlighted value cardio-oncology, demonstrating its protective effects against decline functional capacity cardiovascular complications that may arise oncology patients, either as a result disease itself or side effect chemotherapy. The purpose this review is to elucidate mechanisms clinical conferred by cancer patients. Additionally, it aims...

10.3390/jcm14113724 article EN Journal of Clinical Medicine 2025-05-26

The detection of a coronary artery fistula (CAF) is usually by chance and, because the to-and-fro characters murmur, misdiagnosis patent ductus arteriosus frequently made. Correct diagnosis can only be reached after hemodynamic investigation completed angiography. This lesion often accompanied few or no symptoms in infancy, but may become symptomatic with aging even if shunt small: complications such as endocarditis, rhythm disturbances, aneurysmatic dilation and rupture have been reported....

10.1055/s-2007-1022237 article EN The Thoracic and Cardiovascular Surgeon 1982-06-01
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