- Enzyme Catalysis and Immobilization
- Nanoplatforms for cancer theranostics
- Advanced Sensor and Energy Harvesting Materials
- Microbial Metabolic Engineering and Bioproduction
- Mesoporous Materials and Catalysis
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Asymmetric Hydrogenation and Catalysis
- Luminescence Properties of Advanced Materials
- biodegradable polymer synthesis and properties
- Solid State Laser Technologies
- Photorefractive and Nonlinear Optics
- RNA Interference and Gene Delivery
- Catalysis and Hydrodesulfurization Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Biochemical and Molecular Research
- Polyoxometalates: Synthesis and Applications
- Catalytic Processes in Materials Science
- Chemical Synthesis and Analysis
- Advanced biosensing and bioanalysis techniques
- Protein purification and stability
- Nanomaterials and Printing Technologies
- Advanced Fiber Laser Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Steroid Chemistry and Biochemistry
Harbin Normal University
2023
Zhejiang Sci-Tech University
2022-2023
East China Normal University
2016-2022
Tianjin University of Science and Technology
2022
East China University of Science and Technology
2003-2021
The University of Queensland
2019-2020
Brisbane School of Theology
2019
Lakehead University
2018
Jilin Business and Technology College
2017
Jilin Province Science and Technology Department
2017
Lateral flow immunoassays (LFIAs) have drawn much attention in point-of-care diagnostic applications, and the development of high-performance label materials is key. In this study, impact surface chemistry dendritic mesoporous silica nanoparticles (DMSNs) on their enrichment performance toward quantum dots (QDs) signal amplification resultant DMSNs-QDs as been investigated. A series DMSNs with controllable amino/thiol group densities synthesized. It demonstrated that amino groups are...
A series of alkylpyrimidine-4,6-diol derivatives were designed and synthesized as novel GRP84 agonists based on a high-throughput screening (HTS) hit 1. 6-Nonylpyridine-2,4-diol was identified the most potent agonist GPR84 reported so far, with an EC50 0.189 nM. These will provide valuable tools for study physiological functions GPR84.
In this paper, we report the ion interference tumor therapy strategy by employing specific biological effects of Ba<sup>2+</sup> ions.
Abstract Aluminum‐containing adjuvants used in vaccine formulations suffer from low cellular immunity, severe aggregation, and accumulation the brain. Conventional aluminosilicates widely chemical industry focus mainly on acidic sites for catalytic applications, but they are rarely as adjuvants. Reported here is an innovative “ligand‐assisted steric hindrance” strategy to create a high density of six‐coordinate VI Al−OH groups with basicity dendritic mesoporous silica nanoparticles new...
A simple, practical and governable palladium-catalyzed hydroformylation of terminal arylacetylenes has been disclosed. The reaction proceeds under syngas-free conditions, using readily available glyoxylic acid as the formyl source, mild giving rise to a broad range α,β-unsaturated aldehydes.
Abstract The effects of organic cosolvents on the synthesis ampicillin from phenylglycine methyl ester (PGME) and 6‐amino penicillanic acid (6‐APA) using immobilized Bacillus megaterium penicillin G acylase have been examined. Several were tested for their influence enzyme in terms stability hydrophobicity. Among tested, ethylene glycol was found to increase yield by 39–50%. p K a PGME, hydrolysis synthetase/amidase esterase/amidase ratios also studied. Experimental data indicated that...
Membrane plays significant role in cellular enzymatic reactions. To better understand its function on membrane integral or bound enzymes, DNA origami and frame-guided assembly strategy are combined to construct a given-size, addressable enzyme-containing nanomembrane as heterogeneous reactor explore the catalyst reaction membrane. The enzymes located precisely. This new kind of can enrich hydrophobic substrate molecules aqueous solution embedded enzymes. Otherwise, this shows capability...
Cellulases played an important role in the production of bioenergy and bio-products. from bacteria with some special characteristics drew great attention due to its fast growth speed, wide adaption harsh environment, multi-function cellulases. An endoglucanase gene egls Bacillus velezensis A4 was cloned expressed Escherichia coli BL21 (DE3). The recombinant enzyme Egls partially purified using aqueous two-phase system. highest recovery rate 90.39% at PEG 4000 (25% w/w), phosphate buffer...