A5066422384- Digital Holography and Microscopy
- MRI in cancer diagnosis
- Optical measurement and interference techniques
- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Lung Cancer Treatments and Mutations
- Digital Imaging for Blood Diseases
- Colorectal Cancer Treatments and Studies
- Radiomics and Machine Learning in Medical Imaging
- Microfluidic and Bio-sensing Technologies
- Spinal Fractures and Fixation Techniques
- Advanced X-ray and CT Imaging
- Kruppel-like factors research
- Advancements in Transdermal Drug Delivery
- Advanced Neuroimaging Techniques and Applications
- Infrared Target Detection Methodologies
- Advanced X-ray Imaging Techniques
- Antimicrobial Peptides and Activities
- Protein Degradation and Inhibitors
- Neutropenia and Cancer Infections
- Cancer Immunotherapy and Biomarkers
- Phagocytosis and Immune Regulation
- Atherosclerosis and Cardiovascular Diseases
- Dental Research and COVID-19
- Wound Healing and Treatments
Anhui Medical University
2021-2024
Institute of Biophysics
2024
Chinese Academy of Sciences
2024
University of Chinese Academy of Sciences
2024
Peking University People's Hospital
2023
Peking University
2023
Ruijin Hospital
2023
Shanghai Jiao Tong University
2023
Shandong First Medical University
2014-2022
Hangzhou Hospital of Traditional Chinese Medicine
2022
Objective: Robot-assisted (RA) techniques have been widely investigated in thoracolumbar spine surgery. However, the application of RA methods on cervical surgery is rare due to complex morphology vertebrae and catastrophic complications. Thus, feasibility safety screw placement remain controversial. This study aims evaluate surgery.Methods: A comprehensive search PubMed, Cochrane Library, Embase Database, Web Science, Chinese National Knowledge Databases, Wanfang Database was performed...
The primary aim of this research was to investigate the association between uridine diphosphate glucuronosyltransferase (UGT)1A1 gene polymorphisms and toxicities irinotecan-based regimens in Chinese patients with metastatic colorectal cancer.The study analyzed distribution UGT1A1*28/*6 by polymerase chain reaction amplification pyrosequencing. adverse reactions tumor response were evaluated according National Cancer Institute Common Toxicity Criteria for Adverse Events, Version 3.0,...
Abstract Objectives The present study aims to investigate the efficacy of utilizing three-dimensional (3D) printing technology in concert with Problem-Based Learning (PBL) and Case-Based (CBL) pedagogical approaches educating senior undergraduate clinical medical students on respiratory diseases. Methods A cohort 422 fourth-year medicical from Anhui Medical University, pursuing a five-year program, were arbitrarily segregated into two distinct groups. experimental group was subjected...
Classification of the morphology red blood cells (RBCs) plays an extremely important role in evaluating quality long-term stored blood, as RBC storage lesions such transformation discocytes to echinocytes and then spherocytes may cause adverse clinical effects. Most segmentation classification methods, limited by interference staining procedures poor details, are based on traditional bright field microscopy. In present study, quantitative phase imaging (QPI) technology was combined with deep...
Abstract The production of bacterial toxins and excessive accumulation reactive oxygen species (ROS) can induce localized oxidative stress, triggering an exaggerated immune response that impedes wound healing culminates in chronic wounds. To address this issue, a microneedle (MN) system loaded with copper‐manganese oxide (CMO) is developed to modulate the hyperimmune CMO@MN exhibits excellent antimicrobial anti‐inflammatory properties by effectively killing bacteria, scavenging ROS,...
Quantitative differential phase contrast (qDPC) microscopy can achieve imaging of unlabeled cell samples with high spatial resolution. However, qDPC is easily affected by the noise generated in experiments. In this manuscript, L0-norm regularization was introduced into reconstruction for sparse (L0-qDPC), including quantitative target and samples. After detailed comparison fidelity, contrast, resolution, convergence rate, L0-qDPC method provide a stable without parameter adjustment due to...
The current classical blood smear technique to observe the morphology of single red cells (RBCs) for classification is a laborious and error-prone process. To objectively evaluate cells, we established method computational imaging based on programmable light emitting diode array. By using quantitative differential phase contrast (qDPC), characterized unlabeled RBCs as well smears. focusing comparing difference between stained under multimode microscopic technology, demonstrated that qDPC...
Mucosal-associated invariant T (MAIT) cells are a subset of innate-like that regulate the immune response via rapidly releasing inflammatory factors, including during progression some tumors. However, immunological role MAIT is still unclear in lung cancer. We measured percentage, partial function, and clinical correlation circulating from cancer patients through flow cytometry. Lung displayed high concentration CD4+, CD8+, activated CD38+CD8+MAIT cells, decrease PD1+ double negative (DN)...
Anaplastic lymphoma kinase (ALK) is a highly responsive therapeutic target for
This study aims to estimate the amount of axillary lymph node (ALN) involvement in early-stage breast cancer utilizing a field view (FOV) optimized and constrained undistorted single-shot (FOCUS) diffusion-weighted imaging (DWI) approach, as well whole-lesion histogram analysis.This retrospective analysis involved 81 individuals with invasive cancer. The patients were divided into three groups: N0 (negative ALN metastasis), N1-2 (low metastatic burden 1-2 ALNs), N≥3 (heavy ≥ 3 ALNs) based on...
The purpose of this study was to evaluate endocrine therapy and chemotherapy for first-line, maintenance, second-line treatment hormone receptor-positive HER-2-negative metastatic breast cancer (HR+HER-2-MBC) the relationship between different options survival.The patients included in were all diagnosed with (MBC) at Shandong Cancer Hospital from January 2013 June 2017. Of 951 MBC, 307 HR+HER-2-MBC analysis. progression-free survival (PFS) overall (OS) various modes evaluated using...
The purpose of this study was to verify the effectiveness polylactic acid (PLA) template puncture route planning by comparing preoperative and postoperative dosimetry using computerized tomography (CT)-guided implantation 125 I radioactive seeds.A total 28 patients who underwent seed between January 2018 June 2019 were selected for statistical dosimetry. All received treatment system (TPS) planning, which 13 in experimental 3D group intraoperative PLA route. other 15 traditional control CT...
Oblique illumination imaging can significantly improve the contrast of transparent thin samples. However, in traditional oblique methods, either condenser is offset or a block added to condenser, which makes it complicated and challenged build stable imaging. Herein, we present method measure optimal shading ratio an inverted microscope, develop apparatus for high-speed high-contrast with uniform brightness. At ratio, has better quality than differential interference contrast, characteristic...
Objects: This study aims to identify a morphological indicator of aortic dissection (AD) based on the geometrical characteristics thoracic aorta.Method: We evaluated computed tomographic angiograms 63 samples with AD (22 type A AD, 41 B AD) and 71 healthy samples. Via centerline extraction spatial transformation, entanglement aorta was minimized projected onto optimal plane. The two-dimensional morphology subjected circle fitting. applicability fitting method for prediction verified by...
Abstract Background: This study aims to estimate the amount of axillary lymph node (ALN) involvement in early-stage breast cancer utilizing a field view (FOV) and constrained undistorted single-shot (FOCUS) diffusion-weighted imaging (DWI) approach, as well whole-lesion histogram analysis. Methods: retrospective analysis involved 65 individuals with invasive cancer. The patients were divided into three groups: N 0 (negative ALN metastasis), 1–2 (low metastatic burden 1-2 ALNs), ≥3 (heavy...