A5005804424- Neurobiology and Insect Physiology Research
- Olfactory and Sensory Function Studies
- Insect and Arachnid Ecology and Behavior
- Insect Pheromone Research and Control
- HIV Research and Treatment
- Plant and animal studies
- Microtubule and mitosis dynamics
- Immunotherapy and Immune Responses
- HIV/AIDS Research and Interventions
- Memory and Neural Mechanisms
- Cytokine Signaling Pathways and Interactions
- Insect and Pesticide Research
- Cell Adhesion Molecules Research
- Atherosclerosis and Cardiovascular Diseases
- SARS-CoV-2 and COVID-19 Research
- Biochemical and Structural Characterization
- Amphibian and Reptile Biology
- Cellular Mechanics and Interactions
- Animal Virus Infections Studies
- Advanced Chemical Sensor Technologies
- Zebrafish Biomedical Research Applications
- Animal Behavior and Reproduction
- Mental Health Research Topics
- Phagocytosis and Immune Regulation
- Vascular Malformations Diagnosis and Treatment
University of Hyderabad
2011-2025
Dartmouth College
2023
Indian Institute of Technology Mandi
2023
Alagappa University
2023
National Institutes of Health
1982-2015
National Institute of Mental Health
2004-2015
Office of AIDS Research
2015
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2010-2012
Istituti di Ricovero e Cura a Carattere Scientifico
2007
Heinrich Heine University Düsseldorf
2007
In 1991, the AIDS Task Force of American Academy Neurology published nomenclature and research case definitions to guide diagnosis neurologic manifestations HIV-1 infection. Now, 16 years later, National Institute Mental Health Neurological Diseases Stroke have charged a working group critically review adequacy utility these definitional criteria identify aspects that require updating. This report represents majority view, unanimity was not reached on all points. It reviews our collective...
Odorants are represented as spatiotemporal patterns of spikes in neurons the antennal lobe (AL; insects) and olfactory bulb (OB; vertebrates). These response have been thought to arise primarily from interactions within AL/OB, an idea supported, part, by assumption that receptor (ORNs) respond odorants with simple firing patterns. However, activating AL directly pulses current evoked responses were much less diverse, complex, enduring than elicited odorants. Similarly, models driven...
A monoclonal antibody has been prepared against rat angiotensin-converting enzyme (ACE). By selection for binding to endothelial cells of bovine rather than origin we have obtained a reagent that broad cross-species properties and can at the same time serve as useful marker surface cells. The IgM-producing clone established, alpha-ACE 3.1.1, grown in ascites form yield fluid binds selectively immobilized ACE greater 1:10,000 dilution. use enzyme-linked immunosorbent assays,...
Noisy or spontaneous activity is common in neural systems and poses a challenge to detecting discriminating signals. Here we use the locust answer fundamental questions about noise olfactory system: Where does originate? How this propagated reduced throughout multiple stages of processing? What mechanisms favor detection signals despite presence activity? We found that long observed secondary projection neurons (PNs) originates almost entirely from primary receptor (ORNs) rather than circuit...
On 18 July 2014, the National Institute of Mental Health in collaboration with ViiV Care and Boehringer Ingelheim supported a symposium on HIV eradication what it meant for brain. The was an affiliated event to 20th International AIDS Conference. meeting held Melbourne, Australia, brought together investigators currently working who are neurological complications HIV. purpose bring two fields neurology foster dialogue cross talk move field forward context issues relating brain as potential...
It is important to determine the mechanisms controlling number of neurons in nervous system. Previously, we reported that neuronal activity plays a central role neuron neonatal hippocampus rodents. Neuronal survival requires sustained activation serine–threonine kinase Akt, which initiated by neurotrophins and continued for several hours integrin signaling. Here, focus on CA3 region show apoptosis p53. As wild-type animals, death occurs first postnatal week ends day (P)10 p53−/− mice. During...
Tonic Immobility (TI) is a prolonged immobile condition exhibited by variety of animals when exposed to certain stimuli, and thought be associated with specific state arousal. In our study, we characterize this using the reliably inducible TI grasshopper (Hieroglyphus banian) monitoring abdominal pulsations body movements in response visual auditory stimuli. These are present during 'awake', standing states, but not CO2 anesthetized state. suppression pulsation startle response. The lasted...
Abstract The European honeybee, Apis mellifera is the most common insect model system for studying learning and memory. We establish that olfactory of dorsata , an Asian species honeybee as equivalent to study physiology underlying created Atlas antennal lobe counted number glomeruli in be around 165 which similar other honey bee florea . was found have five antenno-cerebral tracts namely mACT, lACT 3 mlACTS appear identical Intracellular recording showed interneurons exhibit temporally...
<title>Abstract</title> <italic>Hieroglyphus banian</italic> (<italic>H. banian</italic>) is a grasshopper, endemic to South Asia. The optic lobe has been characterized great extent in orthoptera, predominantly using Locust species like <italic>Schistocerca gregaria, Schistocerca americana</italic>, and <italic>Locusta migratoria</italic>, which are closely related each other. In this work, we characterize the anatomical features of associated pathway grasshopper <italic>H. tract-tracing...
Purpose: The objective was to enlist individuals new treatment for generalized anxiety disorder and assess their self-reported quality of life with the World Health Organization’s Quality Life brief version Questionnaire (WHOQoL-BREF). study also aimed compare (QoL) measures pre- post-treatment.Methods: A six-month interventional monitored 60 participants who had never received (GAD) were diagnosed according Diagnostic Statistical Manual Mental Disorders, Fifth Edition (DSM-5) criteria at a...
Abstract Olfactory systems of different species show variations in structure and physiology despite some conserved characteristics. We characterized the olfactory circuit grasshopper Hieroglyphus banian family Acrididae (subfamily: Hemiacridinae) compared it to a well-studied locust, Schistocerca americana Cyrtacanthacridinae), also belonging Acrididae. used vivo electrophysiological, immunohistochemical anatomical (bulk tract tracing) methods elucidate pathway from second order neurons...