A5014259588- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- Intraperitoneal and Appendiceal Malignancies
- Radiomics and Machine Learning in Medical Imaging
- Gynecological conditions and treatments
- Cancer Risks and Factors
- Ultrasound and Hyperthermia Applications
- MRI in cancer diagnosis
- Sarcoma Diagnosis and Treatment
- Colorectal and Anal Carcinomas
- Renal cell carcinoma treatment
- Reproductive Biology and Fertility
- Urinary and Genital Oncology Studies
- Multiple and Secondary Primary Cancers
- Cancer Diagnosis and Treatment
- Genetic factors in colorectal cancer
- Education, Psychology, and Social Research
- Lymphatic Disorders and Treatments
- Pelvic and Acetabular Injuries
- Diverticular Disease and Complications
- Ovarian function and disorders
- Neurofibromatosis and Schwannoma Cases
Charles University
2016-2025
General University Hospital in Prague
2016-2025
Gynecologic Oncology Group
2020
Hillingdon Hospital
2018
Amsterdam UMC Location University of Amsterdam
2018
Masaryk University
2016
KU Leuven
2009-2011
Ziekenhuis Oost-Limburg
2009-2011
Skåne University Hospital
2011
Ocní klinika
2009
Background Despite significant advances in the screening, detection, and treatment of preinvasive cervical lesions, invasive cancer is fifth most common European women. There are large disparities Europe worldwide incidence, management, mortality cancer. Objective The Society Gynaecological Oncology (ESGO), for Radiotherapy (ESTRO), Pathology (ESP) jointly develop clinically relevant evidence-based guidelines order to improve quality care women with across worldwide. Methods ESGO/ESTRO/ESP...
To prospectively assess the diagnostic performance of simple ultrasound rules to predict benignity/malignancy in an adnexal mass and test risk malignancy index, two logistic regression models, subjective assessment ultrasonic findings by experienced examiner masses for which yield inconclusive result.Prospective temporal external validation distinguish benign from malignant masses. The comprised five features (including shape, size, solidity, results colour Doppler examination) a tumour (M...
<b>Objectives</b> To develop a risk prediction model to preoperatively discriminate between benign, borderline, stage I invasive, II-IV and secondary metastatic ovarian tumours. <b>Design</b> Observational diagnostic study using prospectively collected clinical ultrasound data. <b>Setting</b> 24 centres in 10 countries. <b>Participants</b> Women with an (including para-ovarian tubal) mass who underwent standardised examination before surgery. The was developed on 3506 patients recruited 1999...
Abstract Objectives To describe the ultrasound characteristics of endometriomas in pre‐ and postmenopausal patients to develop rules that characterize endometriomas. Methods All included International Ovarian Tumor Analysis (IOTA) studies were used our analysis. Patients with an adnexal mass scanned by experienced sonologists using a standardized research protocol. The gold standard was histology surgically removed mass. gray‐scale Doppler compared those other benign malignant masses. Based...
In 2018, the European Society of Gynecological Oncology (ESGO) jointly with for Radiotherapy and (ESTRO) Pathology (ESP) published evidence-based guidelines management patients cervical cancer. Given large body new evidence addressing cancer, three sister societies decided to update these guidelines. The includes topics provide comprehensive on all relevant issues diagnosis treatment in To serve expert panel (27 experts across Europe) ESGO/ESTRO/ESP nominated practicing clinicians who are...
The European Society of Gynaecological Oncology, the for Medical Oncology (ESMO) and Pathology held a consensus conference (CC) on ovarian cancer 15-16 June 2022 in Valencia, Spain. CC panel included 44 experts management pathology, an ESMO scientific advisor methodologist. aim was to discuss new or contentious topics develop recommendations improve harmonise patients with cancer. Eighteen questions were identified discussion under four main topics: (i) pathology molecular biology, (ii)...
As part of its mission to improve the quality care for women with gynecological cancers across Europe, European Society Gynaecological Oncology (ESGO) first published in 2017 evidence-based guidelines management patients vulvar cancer.To update ESGO based on new evidence addressing cancer and cover topics order provide comprehensive all relevant issues diagnosis treatment cancer.The Council nominated an international development group comprised practicing clinicians who have demonstrated...
In 2018, the European Society of Gynecological Oncology (ESGO) jointly with for Radiotherapy and (ESTRO) Pathology (ESP) published evidence-based guidelines management patients cervical cancer. Given large body new evidence addressing cancer, three sister societies decided to update these guidelines. The includes topics provide comprehensive on all relevant issues diagnosis treatment in To serve expert panel (27 experts across Europe) ESGO/ESTRO/ESP nominated practicing clinicians who are...
Abstract Objectives The aims of the study were to temporally and externally validate diagnostic performance two logistic regression models containing clinical ultrasound variables in order estimate risk malignancy adnexal masses, compare results with subjective interpretation findings carried out by an experienced examiner (‘subjective assessment’). Methods Patients who put forward 19 centers participating study, underwent a standardized transvaginal examination gynecologist or radiologist...
Abstract Objective To evaluate the performance of diagnostic prediction models for ovarian malignancy in all patients with an mass managed surgically or conservatively. Design Multicentre cohort study. Setting 36 oncology referral centres (tertiary a specific gynaecological unit) other types centre. Participants Consecutive adult presenting adnexal between January 2012 and March 2015 by surgery follow-up. Main outcome measures Overall centre discrimination, calibration, clinical utility six...
To describe the clinical and ultrasound characteristics of uterine sarcomas.This was a retrospective multicenter study. From databases 13 centers, we identified patients with histological diagnosis sarcoma available reports images who had undergone preoperative examination between 1996 2016. As first step, each author collected information from original his/her own center on predefined features tumors by reviewing to identify variables not described in report. second 16 examiners reviewed...
ABSTRACT Objective To describe the sonographic features of endometrial cancer in relation to tumor stage, grade and histological type, using International Endometrial Tumor Analysis (IETA) terminology. Methods This was a prospective multicenter study 1714 women with biopsy‐confirmed undergoing standardized transvaginal grayscale Doppler ultrasound examination according IETA protocol, by experienced examiners high‐end equipment. Clinical data were entered into web‐based database. We assessed...
BackgroundSENTIX (ENGOT-CX2/CEEGOG-CX1) is an international, multicentre, prospective observational trial evaluating sentinel lymph node (SLN) biopsy without pelvic dissection in patients with early-stage cervical cancer. We report the final preplanned analysis of secondary end-points: SLN mapping and outcomes intraoperative pathology.MethodsForty-seven sites (18 countries) experience participated SENTIX. preregistered stage IA1/lymphovascular space invasion-positive to IB2 (4 cm or smaller...