Brooke Chapman
A5039981969- Nutrition and Health in Aging
- Clinical Nutrition and Gastroenterology
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Transplantation Techniques and Outcomes
- Diet and metabolism studies
- Intestinal Malrotation and Obstruction Disorders
- Electrolyte and hormonal disorders
- Child Nutrition and Feeding Issues
- Body Composition Measurement Techniques
- Frailty in Older Adults
- Intestinal and Peritoneal Adhesions
- Palliative Care and End-of-Life Issues
- Organ and Tissue Transplantation Research
- Abdominal Surgery and Complications
- Enhanced Recovery After Surgery
- Obesity and Health Practices
- Delphi Technique in Research
- Clostridium difficile and Clostridium perfringens research
- Family and Patient Care in Intensive Care Units
- Bariatric Surgery and Outcomes
- Pharmaceutical studies and practices
- Long-Term Effects of COVID-19
- Pressure Ulcer Prevention and Management
- Polyomavirus and related diseases
Austin Health
2016-2025
The University of Melbourne
2019-2025
University of Colorado Health
2021
Austin Hospital
2019-2020
Sarcopenia is associated with mortality in cirrhosis, but there no gold standard for its diagnosis. The comparative utility of different diagnostic methods unknown. This single-center observational cohort study followed 145 men referred liver transplant evaluation between 2005 and 2012. Muscle mass was estimated by handgrip strength, dual energy X-ray absorptiometry (DEXA) lean mass, single-slice computed tomography (CT) scan at the fourth lumbar vertebra. Recorded outcomes included time to...
Observational studies suggest a beneficial effect of continuous terlipressin infusion (CTI) on ascites and sarcopenia in decompensated cirrhosis with portal hypertension.
Sarcopenia is associated with adverse outcomes in cirrhosis. Branched-chain amino acids (BCAA) target several pathways that lead to muscle loss this population.
Background and aim No marker to categorise the severity of chronic intestinal failure (CIF) has been developed. A 1-year international survey was carried out investigate whether European Society for Clinical Nutrition Metabolism clinical classification CIF, based on type volume intravenous supplementation (IVS), could be an indicator CIF severity. Methods At baseline, participating home parenteral nutrition (HPN) centres enrolled all adults with ongoing due non-malignant disease; demographic...
Abstract Background Preoperative immunonutrition has been proposed to reduce the duration of hospital stay and infective complications following major elective surgery in patients with gastrointestinal malignancy. A multicentre 2 × factorial RCT was conducted determine impact preoperative postoperative versus standard nutrition oesophageal cancer. Methods Patients were randomized before oesophagectomy (IMPACT®) isocaloric/isonitrogenous nutrition, then further after operation nutrition....
Reduced muscle area on CT scan is an independent predictor of mortality in cirrhosis. We examine for the first time relationship between dual energy x-ray absorptiometry (DEXA) lean mass parameters outcomes cirrhotic men awaiting liver transplantation.We retrospectively reviewed DEXA scans performed during transplant assessment 2001 and 2016. Baseline data including presence ascites MELD score were recorded. measures adjusted height. The primary outcome was 12-month wait-list mortality.Four...
Abstract Background The number of people diagnosed with chronic intestinal failure (CIF) worldwide is low. condition clinically complex to manage and resource intense. Guidance on best‐practice staffing levels lacking. This paper proposes a methodology for determining dietetic adult CIF estimate allowing patients access care. Methods After undertaking literature search, novel method developing recommended adequate within services was utilized. included (1) mapping the current patient journey...
Several chemotherapeutic regimens and radiation therapy, if delivered to the oral mucosa, are associated with a high frequency of mouth lesions. The cause this side effect is not known for certain, but in past studies it has sometimes been ability culture herpes simplex virus type 1 from mouth. In double-blind prospective trial, patients head neck tumors treated chemotherapy or therapy were either acyclovir placebo. Although culture-positive was low untreated group, significantly lower,...
•Malnutrition and poor muscle strength are highly prevalent in cirrhotics with hepatorenal syndrome.•Terlipressin infusion increased energy protein intake patients syndrome.•Handgrip continued to increase every day of terlipressin therapy•Medium long-term was safe efficacious as a bridge liver transplant. Background & AimsPortal hypertension contributes the pathogenesis malnutrition sarcopenia cirrhosis via multiple mechanisms. Terlipressin is vasopressin analogue that we administer...
Abstract Background Malnutrition is prevalent in patients undergoing gastrointestinal (GI) surgery and has been linked to adverse outcomes. The present study aimed determine the association between early post‐operative nutritional status/risk, management clinical Methods A prospective observational was conducted GI surgical with a minimum 3‐day length of stay (LOS). Data on patient demographics, outcomes were collected. Four markers status risk assessed: preoperative weight loss, nutrition...
Abstract Aim This study assessed the responsiveness and convergent validity of two preference-based measures; newly developed cancer-specific EORTC Quality Life Utility Measure-Core 10 dimensions (QLU-C10D) relative to generic three-level version EuroQol 5 (EQ-5D-3L) in evaluating short-term health related quality life (HRQoL) outcomes after esophagectomy. Methods Participants were enrolled a multicentre randomised controlled trial determine impact preoperative postoperative immunonutrition...
Background and Aims: Most patients with decompensated cirrhosis fail to meet their nutrition targets. The impact of nasogastric feeding (NGF) on malnutrition in remains unknown. This study aims assess the pretransplant NGF pre–liver transplant post–liver outcomes. Approach Results: single-center, prospective randomized controlled trial 55 severe low handgrip strength (HGS) compared a standard high-energy high-protein diet plus supplemental nocturnal while awaiting transplant. primary outcome...
Sarcopenia in cirrhosis is associated with poor outcomes. While transjugular intrahepatic portosystemic shunt (TIPS) insertion improves radiological measures of muscle mass, its impact on function, performance and frailty has not been evaluated.Patients referred for TIPS were prospectively recruited followed 6 months. L3 CT scans used to calculate skeletal adipose tissue parameters. Handgrip strength, Liver Frailty Index short physical battery serially monitored. Dietary intake, insulin...
Abstract Aim: Pressure ulcers are a serious secondary consequence of spinal cord injuries. The objective the present study was to determine whether an arginine‐containing nutritional supplement can reduce healing time pressure in people with injuries compared those not consuming until full wound healing. Methods: Thirty‐four injured patients grade 2, 3 or 4 ulcer were prescribed two 237 mL tetrapaks/day containing additional protein, arginine, zinc and vitamin C. assessed Ulcer Scale for...