A5038149615- Coronary Interventions and Diagnostics
- Peptidase Inhibition and Analysis
- Hormonal and reproductive studies
- Acute Myocardial Infarction Research
- Reproductive Health and Technologies
- Pulmonary Hypertension Research and Treatments
- Chemical Synthesis and Analysis
- Management of metastatic bone disease
- Liver Disease Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Cardiovascular Function and Risk Factors
- Reproductive Biology and Fertility
- Glycosylation and Glycoproteins Research
- Cardiac Valve Diseases and Treatments
- Advanced Radiotherapy Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Ovarian function and disorders
- Advances in Oncology and Radiotherapy
- Respiratory and Cough-Related Research
- Trypanosoma species research and implications
- Cardiac Structural Anomalies and Repair
- RNA and protein synthesis mechanisms
- Carbohydrate Chemistry and Synthesis
- Asthma and respiratory diseases
Azienda USL di Bologna
2021-2025
Istituti di Ricovero e Cura a Carattere Scientifico
1989-2025
University of Bologna
2015-2024
Policlinico S.Orsola-Malpighi
2007-2023
Kantar Health (Brazil)
2019
GynePro Medical
2018
University of Florence
1999-2006
University of Palermo
2001-2002
University of Salerno
2001
Istituto Giannina Gaslini
1989
A few studies have assessed the short-term effects of low-dose nicotine e-cigarettes, while data about nicotine-free e-cigarettes (NF e-cigarettes) are scanty. Concerns been expressed use NF because high concentrations propylene glycol and other compounds in e-cigarette vapor. This laboratory-based study was aimed to compare ad libitum a or traditional cigarette for 5 min healthy adult smokers (n = 10) non-smokers 10). The main outcome measures were pulmonary function tests, fraction exhaled...
Background Home blood pressure measurement has gained increasing importance for the management of hypertensive patients. The aim our study was to compare levels clinic (CBP), ambulatory (ABP), and home (HBP) measurements, their relationships with various indexes target organ damage in I–II grade essential hypertension. Design methods Thirty-eight hypertensives underwent evaluation clinic, pressures. Each patient recorded HBP 2 days a digital BP monitor three times daily, first time on same...
Background and aim No marker to categorise the severity of chronic intestinal failure (CIF) has been developed. A 1-year international survey was carried out investigate whether European Society for Clinical Nutrition Metabolism clinical classification CIF, based on type volume intravenous supplementation (IVS), could be an indicator CIF severity. Methods At baseline, participating home parenteral nutrition (HPN) centres enrolled all adults with ongoing due non-malignant disease; demographic...
Abstract Objectives Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is recommended for measuring circulating steroids. However, assays display technical heterogeneity. So far, reproducibility of corticosteroid LC-MS/MS measurements has received scant attention. The aim the study was to compare cortisol, 17OH-progesterone and aldosterone from nine European centers assess performance according external quality assessment (EQA) materials calibration. Methods Seventy-eight patient...
Acute abdominal pain (AAP) is one of the most common causes referral to an emergency department (ED), but information about its impact limited.The objectives this article are define prevalence AAP among ED visits in a large university hospital and analyze main clinical features.All patients admitted at Sant'Orsola, Malpighi University Hospital Bologna on 12 priori selected sample days 2013 were included. General data recorded for each patient. A total 192 variables patient with pain.During...
Abstract Objectives Current liquid chromatography-tandem mass spectrometry (LC-MS/MS) applications for circulating androgen measurements are technically diverse. Previously, variable results have been reported testosterone. Data scarce androstenedione and absent dehydroepiandrosterone sulfate (DHEAS). We assessed the agreement of androstenedione, DHEAS testosterone LC-MS/MS among nine European centers explored benefits calibration system unification. Methods Androgens were measured twice by...
To evaluate the role of ECG in differential diagnosis between Anderson-Fabry disease (AFD) and hypertrophic cardiomyopathy (HCM).In this multicentre retrospective study, 111 AFD patients with left ventricular hypertrophy were compared HCM, matched for sex, age maximal wall thickness by propensity score. Independent predictors identified multivariate analysis, a multiparametric score-based algorithm was developed.Short PR interval, prolonged QRS duration, right bundle branch block (RBBB), R...
Prevention is essential to reduce Colorectal Cancer (CRC) mortality. We previously reported a panel of four genes: CEACAM6, LGALS4, TSPAN8, COL1A2 (CELTiC) able discriminate patients with CRC. Here, we assessed the CELTiC by quantitative polymerase chain reaction, in blood 174 healthy subjects, who resulted negative faecal immunochemical test (FITN). Using non-parametric statistic and multinomial logistic models, FITN were compared analysed subjects: 36 false positive FIT (NFIT), at...
Abstract Purpose The main purpose and research question of the study are to compare efficacy high-security closed versus open devices for human oocytes’ vitrification. Methods A prospective randomized was conducted. total 737 patients attending Infertility IVF Unit at S.Orsola University Hospital (Italy) between October 2015 April 2020 were randomly assigned two groups. 368 group 1 (High-Security Vitrification™ - HSV) 369 2 (Cryotop® system). Oocyte survival, fertilization, cleavage,...
Background: The European Society for Clinical Nutrition and Metabolism database chronic intestinal failure (CIF) was analyzed to investigate factors associated with nutritional status the intravenous supplementation (IVS) dependency in children. Methods: Data collected: demographics, CIF mechanism, home parenteral nutrition program, z-scores of weight-for-age (WFA), length or height-for-age (LFA/HFA), body mass index-for-age (BMI-FA). IVS calculated as ratio daily total energy over estimated...
Background Haemodynamic variables like right atrial pressure (RAP), cardiac index (CI), stroke volume (SVI) and mixed venous oxygen saturation ( S vO 2 ) predict survival in patients with pulmonary arterial hypertension (PAH). However, there is the need to identify further prognostic haemodynamic parameters as well redefine their role PAH risk stratification compared current tools non-invasive parameters. Methods This cohort study includes treatment-naïve assessed at baseline after...
Abstract Aims Left ventricular (LV) ring-like scar on cardiac magnetic resonance (CMR) has been linked to malignant arrhythmias in patients with non-ischaemic cardiomyopathy. This study aimed perform a comprehensive evaluation of this phenotype and identify risk factors for life-threatening arrhythmic events (LAEs), composite sudden death (SCD), aborted SCD, sustained tachycardia. Methods results One hundred fifteen [median age 39 (interquartile range, IQR, 28–52), 42% females] were...
The authors compared the risk of cerebrovascular events (CVE) with self-expanding vales (SEV) vs balloon-expandable valves (BEV) in patients or without peripheral artery disease (PAD), stratified by access route and complexity PAD (Hostile score). PAD-related CVE between SEV BEV was investigated using data from HOSTILE Registry, an observational study including 1707 severe undergoing transcatheter aortic valve replacement (TAVR) via different routes. relative a meta-analysis randomized...
Background: Thoracic ultrasound (TUS) has emerged as a viable alternative of computed tomography (CT) for pneumothorax diagnosis. Ultrasound elastography (USE), technique assessing tissue elasticity, recently been proposed novel tool evaluation. Methods: This prospective, monocentric, observational study aimed to compare the diagnostic accuracy static and dynamic USE with TUS in detecting iatrogenic after CT-guided transthoracic needle aspiration (TTNA). Results: Thirty-two patients were...
To study the efficacy and efficiency of a "universal warming protocol" for vitrified human embryos, based on subsequent steps with 1 0.5 M concentration extracellular cryoprotectant (ECCP).
Abstract Objective We investigated the contribution to sporadic focal epilepsies ( FE ) of ultrarare variants in genes coding for components complexes regulating mechanistic Target Of Rapamycin mTOR )complex 1 mTORC 1). Methods collected genetic data 121 Italian isolated cases and 512 controls by Whole Exome Sequencing WES single‐molecule Molecular Inversion Probes (sm MIP s) targeting 10 GATOR 1, 2, TSC complexes. collapsed “qualifying” (ultrarare predicted be deleterious or loss function)...
Prognostic classifications for patients treated with sorafenib hepatocellular carcinoma (HCC) facilitate stratification in trials and inform clinical decision making. Recently, 3 different prognostic models (hepatoma arterial-embolization prognosis [HAP] score, advanced HCC [SAP] Prediction Of Survival Advanced Sorafenib-treated [PROSASH]-II) have been proposed specifically sorafenib. This study aimed to compare the performance of scores.We analyzed a large prospective database gathering...
Aims To investigate gender difference in mortality among patients with ST-segment elevation myocardial infarction (STEMI) treated primary percutaneous angioplasty (PPCI). Methods We analyzed data from the prospective registries of two hub PPCI centres over a 10-year period to assess role female as an independent predictor both all-cause and cardiac death at 30 days 1 year. account for all confounding variables, propensity score (PS)-adjusted multivariable Cox regression model PS-matched...