A5079273668- HIV Research and Treatment
- HIV/AIDS Research and Interventions
- HIV/AIDS drug development and treatment
- Immunotherapy and Immune Responses
- Antibiotic Use and Resistance
- HIV/AIDS Impact and Responses
- Immune Cell Function and Interaction
- HIV-related health complications and treatments
- HIV, Drug Use, Sexual Risk
- Chronic Disease Management Strategies
- Hepatitis B Virus Studies
- Pneumonia and Respiratory Infections
- Respiratory viral infections research
- Influenza Virus Research Studies
- Multiple Myeloma Research and Treatments
- Acute Myeloid Leukemia Research
- Infective Endocarditis Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Cell Adhesion Molecules Research
- Diagnosis and treatment of tuberculosis
- Drug-Induced Adverse Reactions
- Syphilis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Emergency and Acute Care Studies
- SARS-CoV-2 and COVID-19 Research
Universitair Ziekenhuis Brussel
2012-2023
Vrije Universiteit Brussel
1989-2021
Erasmus Hospital
2012-2021
Northwestern University
2014
KU Leuven
2013
Universidade Nova de Lisboa
2013
Centro Hospitalar de Lisboa Ocidental
2013
Rega Institute for Medical Research
2013
Hospital de Egas Moniz
2013
Leefmilieu Brussel
2013
Spirituality/religion serves important roles in coping, survival and maintaining overall wellbeing within African cultures communities, especially when diagnosed with a chronic disease like HIV/AIDS that can have profound effect on physical mental health. However, spirituality/religion be problematic to some patients cause caregiving difficulties. The objective of this paper was examine the role as source strength, resilience among sub-Saharan (SSA) migrant women HIV/AIDS. A qualitative...
Patients with HIV not only have to deal the challenges of living an incurable disease but also dilemma whether or disclose their status partners, families and friends. This study explores extent which sub-Saharan African (SSA) migrant women in Belgium positive status, reasons for disclosure/non-disclosure how they disclosure. A qualitative consisting interviews twenty-eight SSA HIV/AIDS was conducted. Thematic content analysis employed identify themes as emerged. Our reveals that these...
Three commercial assays for quantifying plasma human immunodeficiency virus type 1 (HIV-1) RNA were evaluated. The differed in their sample volumes, the means of preparing samples, and methods amplification detection. Plasma samples obtained from 36 HIV-1-infected patients representing all stages HIV-1 infection analyzed as coded specimens. Measurement baseline levels revealed no significant difference sensitivity between three assays. also applied to quantitation who changing antiretroviral...
Recently we reported the expression of human natural killer cell associated antigen CD56 (Leu 19/NKH1) in plasma cells a majority multiple myeloma (MM) patients. is known to be an isoform neural adhesion molecule N-CAM which involved homotypic adhesive interactions. By immunophenotyping using four specific monoclonal antibodies and immunoprecipitation analysis here confirm that Leu 19 expressed by identical corresponds 145 kDa isoform. Because possible biological role molecules on cells,...
Stigma and discrimination within health care settings remain a public challenge across diverse cultural environments may have deleterious effects on mental physical health. This study explores the causes, forms consequences of HIV-related stigma among migrant sub-Saharan African women living with HIV in Belgium. A qualitative was conducted 44 HIV-positive between April 2013 December 2014 Data were analysed using thematic content analysis. Twenty-five reported overt fifteen witnessing...
In the adult brain, neural stem cells (NSC) must migrate to express their neuroplastic potential. The addition of recombinant reelin human NSC (HNSC) cultures facilitates neuronal retraction in neurospheroid. Because we detected reelin, alpha3-integrin receptor subunits, and disabled-1 immunoreactivity HNSC cultures, it is possible that integrin-mediated signal transduction operative these cultures. To investigate whether important regulation migration, injected HNSCs into lateral ventricle...
Long-term sequelae of COVID-19 can result in reduced functionality the central nervous system and substandard quality life. Gaining insight into recovery trajectory admitted patients on their cognitive performance global structural brain connectivity may allow a better understanding diseases' relevance.To assess whole-brain former non-intensive-care unit (ICU)- ICU-admitted survivors over 2 months following hospital discharge correlate measures to performance.Participants underwent Magnetic...
To investigate whether B lymphocytes are involved in the malignant cell clone of multiple myeloma (MM), we performed immunoglobulin gene rearrangement analysis mononuclear cells and separated lymphocytes, isolated from bone marrow peripheral blood MM patients. The were by immunomagnetic beads, coated with an HLA class II specific antibody. Southern blot a JH probe revealed three out seven patients identical rearrangements when compared to plasma cells. Out 10 patients, two high tumour burden...
One of the consequences HIV infection is a progressive loss T cell functions, resulting in decreased cytokine secretion and proliferation an increased sensitivity to apoptosis. Therefore, successful therapeutic vaccination approaches should aim at restoring functionality existing HIV-specific cells, as well efficiently induce potent, cells from naïve cells. In this study, we wanted determine stimulatory capacity DCs coelectroporated with mRNA encoding for different costimulatory molecules...
RegaDB is a free and open source data management analysis environment for infectious diseases. allows clinicians to store, manage analyse patient data, including viral genetic sequences. Moreover, provides researchers with mechanism collect in uniform format offers them canvas make newly developed bioinformatics tools available virologists through user friendly interface.Source code, binaries documentation are on http://rega.kuleuven.be/cev/regadb. written the Java programming language,...
Seasonal human coronaviruses (hCoVs) broadly circulate in humans. Their epidemiology and effect on the spread of emerging has been neglected thus far. We aimed to elucidate burden disease seasonal hCoVs OC43, NL63, 229E patients primary care hospitals Belgium between 2015 2020.We retrospectively analysed data from national influenza surveillance networks during winter seasons 2015-20. Respiratory specimens were collected through severe acute respiratory infection (SARI) influenza-like...
Septic arthritis of the sternoclavicular joint: an uncommon infection joint is rare and often occurs in patients with predisposing factors such as intravenous drug use, diabetes mellitus, trauma, or elsewhere body. It presents mostly insidiously can lead to serious complications osteomyelitis mediastinitis, primarily caused by Staphylococcus aureus. Treatment involves antibiotics, drainage, severe cases, resection. We present case a 74-year-old man neck thoracic pain lasting for one week....
The Belgian HIV epidemic is largely concentrated among men who have sex with and Sub-Saharan Africans. We studied the continuum of care those diagnosed living in Belgium its associated factors. Data on new diagnoses 2007–2010 HIV-infected patients 2010–2011 were analysed. Proportions estimated for each sequential stage factors attrition at studied. Of all 2011, an 98.2 % linked to care, 90.8 retained 83.3 received antiretroviral therapy 69.5 had undetectable viral load (<50 copies/ml). After...
This study is the first prospective to assess prevalence, epidemiology, and risk factors of HIV-1 drug resistance in newly diagnosed HIV-infected patients Belgium. In January 2003 it was initiated as part pan-European SPREAD program, continued thereafter for four inclusion rounds until December 2006. Epidemiological, clinical, behavioral data were collected using a standardized questionnaire genotypic testing done on sample taken within 6 months diagnosis. Two hundred eighty-five included....