A5046958500- Identification and Quantification in Food
- CRISPR and Genetic Engineering
- Genetically Modified Organisms Research
- Histone Deacetylase Inhibitors Research
- Meat and Animal Product Quality
- Animal Genetics and Reproduction
- Genetic Mapping and Diversity in Plants and Animals
- Food Supply Chain Traceability
- Plant Molecular Biology Research
- Legume Nitrogen Fixing Symbiosis
- Plant Stress Responses and Tolerance
- Nematode management and characterization studies
- Epigenetics and DNA Methylation
- Natural product bioactivities and synthesis
- Wheat and Barley Genetics and Pathology
- Photosynthetic Processes and Mechanisms
- Sperm and Testicular Function
- MicroRNA in disease regulation
- Biofuel production and bioconversion
- Phytochemistry and Biological Activities
- Marine Invertebrate Physiology and Ecology
- Lipid metabolism and biosynthesis
- Infant Nutrition and Health
- Orbital Angular Momentum in Optics
- Cancer Mechanisms and Therapy
Hainan General Hospital
2024-2025
Air Force Medical University
2009-2025
Hainan Medical University
2024-2025
Nanjing Traditional Chinese Medicine Hospital
2025
Changzhou No.2 People's Hospital
2023-2025
Gansu Agricultural University
2003-2024
Guangdong Pharmaceutical University
2017-2024
Hebei Academy of Agriculture and Forestry Sciences
2022-2024
Yangzhou University
2024
Xuzhou Medical College
2024
Cancer-associated fibroblasts (CAFs) are one of the most enriched components Hepatocellular carcinoma (HCC) microenvironment, which tightly related to metastasis and invasion HCC. We identified a mechanism by CAF-derived chemokine CCL5 enhanced HCC triggering HIF1α/ZEB1 axis. demonstrated that CAFs derived from tissues promoted migration cells facilitated lung NOD/SCID mice. Then antibody array elucidated higher level secreted than paracancerous tissue (PTFs). Mechanistically, we found...
Improving the yield by modifying plant architecture was a key step during crop domestication. Here, we show that 110-kb deletion on short arm of chromosome 7 in Asian cultivated rice (Oryza sativa), which is closely linked to previously identified PROSTRATE GROWTH 1 (PROG1) gene, harbors tandem repeat seven zinc-finger genes. Three these genes regulate architecture, suggesting also promoted critical transition from prostrate growth and low wild (O. rufipogon) erect high rice. We refer this...
Epidemiological evidence connecting cooking fuel use to metabolic syndrome (MetS) is lacking. Solid usage and MetS prevalence were prospectively investigated in this study. We included participants 2011 2015 from the China Health Retirement Longitudinal Study (CHARLS) data. Through cross-sectional longitudinal studies, we found that of solid fuels reduced risk compared with clean (cross-sectional study: 2011: Odds ratio (OR): 0.819, 95 %confidence interval (CI): 0.747-0.897, P < 0.001; 2015:...
Epigallocatechin-3-gallate (EGCG), a bioactive polyphenol in green tea, exerts antiapoptotic activity and prevents tissue damage against different stimuli. Herein, we investigated the effects of EGCG treatment to simultaneously improve spermatogenesis following ionizing radiation (IR) (at dose 2 Gy). Mice were intraperitoneally injected with 50 mg/kg or vehicle control 3 days prior irradiation, lasted intermittently for 24 days. Supplement exogenous protected short-term germ cell loss...
Summary Nonspecific lipid transfer proteins (ns LTP s) play critical roles in plant development and response to abiotic stresses. Here, we found that a rice protein, Os LTPL 159, was associated with cold tolerance at the early seedling stage. Overexpression of an 159 IL 112 allele from cold‐tolerant introgression line either japonica variety Zhonghua17 ( ZH 17) or indica Teqing background dramatically enhanced tolerance. In addition, down‐regulation expression 17 by RNA interference i)...
Soil salinity is a common abiotic stress affecting crop productivity. To identify favorable alleles from wild rice (Oryza rufipogon Griff.) that enhance tolerance of (O. sativa L.), set introgression lines were developed. The derived an O. accession collected Chaling (Hunan Province, China) as the donor, and widely-grown indica cultivar 93-11 recipient. Through evaluating salt 285 at seedling stage, total 10 quantitative trait loci (QTLs) related to identified on chromosomes 1, 5, 7 9–12,...
An effective and trustworthy traceability system contributes to improving food quality safety responds consumers' demand for provenance information. Safe meat its products are crucial consumers society. Livestock feeding regime geographical origin closely related the properties of animal food, but information is often invisible consumers, which makes easier use fraudulent practices throughout whole supply chain. Technologies their proper in systems important foods. essential component an...
The primary goal of modern wheat breeding is to develop new high-yielding and widely adaptable varieties. We analyzed four yield-related agronomic traits in 502 accessions under normal conditions (NC) drought treatment (DT) over three years. genome-wide association analysis identified 51 nine drought-resistance-related QTL, including 13 for the thousand-grain weight (TGW), 30 grain length (GL), width (GW), five spike (SL) stress tolerance index (STI) QTL wheat. These containing 72 single...
Cardiac aging represents an independent risk factor for aging-associated cardiovascular diseases. Although evidence suggests association between NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome formation numerous diseases, its role in cardiac remains largely unclear.
// Xiao-hui Huang 1,* , Wei-hua Jian 2,3* Zhao-feng Wu 1,2 Jie Zhao 1 Hua Wang Wen Li and Jin-tang Xia 2,3 Laboratory of General Surgery, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China 2 Department Third Guangzhou Medical 3 Municipal People's * These authors contributed equally to this work Correspondence: email: Li, Keywords : Macrophage migration inhibitory factor;hepatocellular carcinoma;cyclin D1; RNA interference; proliferation Received May 3, 2014...
This study was performed to explore other potential mechanisms underlying hemolysis in addition pore-formation of tentacle extract (TE) from the jellyfish Cyanea capillata. A dose-dependent increase observed rat erythrocyte suspensions and hemolytic activity TE enhanced presence Ca2+, which attenuated by Ca2+ channel blockers (Diltiazem, Verapamil Nifedipine). Direct intracellular after treatment confocal laser scanning microscopy, could be depressed Diltiazem. The osmotic protectant...
The formation of by-products, mainly acetone in acetone-butanol-ethanol (ABE) fermentation, significantly affects the solvent yield and downstream separation process. In this study, we genetically engineered Clostridium acetobutylicum XY16 isolated by our lab to eliminate production altered ABE isopropanol-butanol-ethanol (IBE). Meanwhile, process optimization under pH control strategies supplementation calcium carbonate were adopted investigate interaction between reducing force metabolic...
The estrogen receptor alpha (ERα) plays an important role in male reproduction and fertility. Its activity is modulated by phosphorylation of multiple amino acid residues. ERα phosphorylated at serine 305 (S305) human cells (homologous with 309 mice) induces ligand-independent activity. Here, we studied the effect S309 on reproductive function mice. ERα309 (p.S309A, ERαS309A) knock-in (KI) mice were generated homologous recombination mouse embryonic stem (ES) cells. S309A KI males subfertile...
Background Although existing studies have identified some genetic loci associated with chronic obstructive pulmonary disease (COPD) susceptibility, many variants remain to be discovered. The aim of this study was further explore the potential relationship between IL18R1 single nucleotide polymorphisms (SNPs) and COPD risk.