A5024962526- Global Maternal and Child Health
- Child Nutrition and Water Access
- Emergency and Acute Care Studies
- Healthcare Policy and Management
- Primary Care and Health Outcomes
- Pneumonia and Respiratory Infections
- Healthcare Systems and Reforms
- Infant Development and Preterm Care
- Malaria Research and Control
- Health Policy Implementation Science
- Health Systems, Economic Evaluations, Quality of Life
- Neonatal Respiratory Health Research
- Family and Patient Care in Intensive Care Units
- Global Health Workforce Issues
- Child and Adolescent Health
- Software Engineering Research
- Mobile Health and mHealth Applications
- Electronic Health Records Systems
- Maternal and Neonatal Healthcare
- Patient Satisfaction in Healthcare
- Mosquito-borne diseases and control
- Hemoglobinopathies and Related Disorders
- Vaccine Coverage and Hesitancy
- Global Health and Surgery
- Advanced Software Engineering Methodologies
University of Oxford
2016-2025
Kenya Medical Research Institute
2016-2025
University of Louisville
2025
Neurological Surgery
2025
Oxford BioMedica (United Kingdom)
2025
Wellcome Trust
2014-2024
Nuffield Health
2018-2024
Northland District Health Board
2023-2024
Center for Assessment
2024
King's College London
2023
There are few epidemiologic data on invasive bacterial infections among children in sub-Saharan Africa. We studied every acute pediatric admission to a rural district hospital Kenya examine the prevalence, incidence, types, and outcome of community-acquired bacteremia.Between August 1998 July 2002, we cultured blood from 19,339 inpatients calculated incidence bacteremia basis population served by hospital.Of total 1783 infants who were under 60 days old, 228 had (12.8 percent), as did 866...
Timely access to emergency care can substantially reduce mortality. International benchmarks for hospital have been established guide ambitions universal health by 2030. However, no Pan-African database of where hospitals are located exists; therefore, we aimed complete a geocoded inventory services in Africa relation how populations might these 2015, with focus on women child bearing age.
Background The RTS,S/AS01E malaria vaccine (RTS,S) was introduced by national immunisation programmes in Ghana, Kenya, and Malawi 2019 large-scale pilot schemes. We aimed to address questions about feasibility impact, assess safety signals that had been observed the phase 3 trial included an excess of meningitis cerebral cases RTS,S recipients, possibility deaths among girls who received than controls, inform decisions wider use. Methods In this prospective evaluation, 158 geographical...
Severe malnutrition has a high mortality rate among hospitalized children in sub-Saharan Africa. However, reports suggest that is often poorly assessed. The World Health Organization recommends using weight for height, but this method problematic and not undertaken practice. Mid upper arm circumference (MUAC) the clinical sign "visible severe wasting" are simple inexpensive methods have been evaluated setting.To evaluate MUAC visible wasting as predictors of inpatient at district hospital...
With strict adherence to international recommended treatment guidelines, the case fatality for severe malnutrition ought be less than 5%. In African hospitals, rates of 20% are common and often attributed poor training faulty management. Improving outcome will depend upon identification those at greatest risk targeting limited health resources. We retrospectively examined major factors associated with early (<48 h) late in-hospital death in children aim identifying admission features that...
ContextHaemophilus influenzae type b (Hib) conjugate vaccine is not perceived as a public health priority in Africa because data on Hib disease burden and effectiveness are scarce. immunization was introduced Kenyan infants 2001.ObjectiveTo define invasive incidence program Kenya.Design, Setting, PatientsCulture-based surveillance for at Kilifi District Hospital from 2000 through 2005 linked to demographic of 38 000 children younger than 5 years District, Kenya. Human immunodeficiency virus...
To evaluate the accuracy of routine malaria microscopy, and appropriate use interpretation slides under operational conditions in Kenya.Cross-sectional survey, using a range quality care assessment tools, at government facilities with microscopy two Kenyan districts different intensity transmission. All patients older than 5 years presenting to outpatient departments were enrolled. Two expert microscopists assessed slide results.We analysed 359 consultations performed by 31 clinicians 17...
Metabolic acidosis is the best predictor of death in children with severe falciparum malaria; however, its treatment presents a therapeutic dilemma, because and hypovolemia may coexist coma, which can be associated elevated intracranial pressure. We postulated that volume resuscitation albumin might correct lower risk precipitating cerebral edema than crystalloid. In an open-label, randomized, controlled trial, we compared safety to saline Kenyan malaria.We randomly assigned malaria...
Une traduction en français de ce résumé figure à la fin l'article.Al final del artículo se facilita una traducción al español. املقالة. لهذه الكامل النص نهاية يف الخالصة العربية الرتجمةObjective To evaluate the relative effectiveness of different policies in attracting nurses to rural areas Kenya, South Africa and Thailand using data from a discrete choice experiment (DCE).Methods A labelled DCE was designed model both financial non-financial strategies attract areas.Data...
Human immunodeficiency virus (HIV) infection, malnutrition, and invasive bacterial infection (IBI) are reported among children with severe malaria. However, it is unclear whether their cooccurrence falciparum parasitization disease happens by chance or association in areas where malaria endemic.
In developing countries referral of severely ill children from primary care to district hospitals is common, but hospital often poor quality. However, strategies change multiple paediatric practices in rural have rarely been evaluated.This cluster randomized trial was conducted eight Kenyan hospitals, four which were randomly assigned a full intervention aimed at improving quality clinical (evidence-based guidelines, training, job aides, local facilitation, supervision, and face-to-face...
In developing countries, there are few data that characterize the disease burden attributable to respiratory syncytial virus (RSV) and clearly define which age group target for vaccine intervention.Six hundred thirty-five children, recruited during period 2002-2003, were intensively monitored until each experienced 3 epidemics of RSV infection. infection was diagnosed using immunofluorescence nasal washing specimens collected at episode acute Incidence estimates adjusted seasonality...
Organizational factors are considered to be an important influence on health workers' uptake of interventions that improve their practices. These additionally influenced by operating at individual and broader system levels. We sought explore contextual influences worker motivation, a factor may modify the effect intervention aimed changing clinical practices in Kenyan hospitals.Franco LM, et al's (Health sector reform public motivation: conceptual framework. Soc Sci Med. 2002, 54: 1255-66)...
Background.Although necessary for developing a rationale vaccination, the burden of severe respiratory syncytial virus (RSV) disease in children resource-poor settings remains poorly defined. Methods.We conducted prospective surveillance and very pneumonia aged <5 years admitted from 2002 through 2007 to Kilifi district hospital coastal Kenya. Nasal specimens were screened RSV antigen by immunofluorescence. Incidence rates estimated well-defined population. Results.Of 25,149 admissions, 7359...
We wanted to try account for worker motivation as a key factor that might affect the success of an intervention improve implementation health practices in eight district hospitals Kenya. In absence available tools, we therefore aimed develop tool could enable rapid measurement at baseline and subsequent points during 18-month study. After literature review, self-administered questionnaire was developed assess outcomes determinants Kenyan government hospital staff. The initial included 23...
Joy Lawn and colleagues used a systematic process developed by the Child Health Nutrition Research Initiative (CHNRI) to define rank research options reduce mortality from intrapartum-related neonatal deaths (birth asphyxia) year 2015.
Background: The Kenyan government, working with international partners and local organizations, has developed an eHealth strategy, specified standards, guidelines for electronic health record adoption in public hospitals implemented two major information technology projects: District Health Information Software Version 2, collating national care indicators a rollout of the KenyaEMR International Quality Care Management Systems, managing 600 HIV clinics across country. Following these...
► Since 2013, Kenya's public health sector has been affected by frequent short strikes, culminating in nationwide strikes lasting a total of 250 days doctors and nurses span 11 months 2016/17.► Health professionals have the right to go on strike, but their crippled services with almost no hospital inpatient being provided, thus violating people's healthcare.► To avoid similar instances future, mechanisms should be established for dispute resolution, anticipating pre-empting changes within...