Rui Ruan

ORCID: 0000-0002-7607-7325
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About
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Research Areas
  • Reproductive biology and impacts on aquatic species
  • Aquaculture Nutrition and Growth
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Aquaculture disease management and microbiota
  • Fish Ecology and Management Studies
  • Genetic diversity and population structure
  • Nonlinear Optical Materials Studies
  • Nonlinear Optical Materials Research
  • Animal Genetics and Reproduction
  • Fish Biology and Ecology Studies
  • Marine animal studies overview
  • Chromosomal and Genetic Variations
  • Genomics and Phylogenetic Studies
  • Marine Bivalve and Aquaculture Studies
  • Liquid Crystal Research Advancements
  • Bone Tissue Engineering Materials
  • Environmental DNA in Biodiversity Studies
  • TGF-β signaling in diseases
  • Sperm and Testicular Function
  • Photochromic and Fluorescence Chemistry
  • Bone and Dental Protein Studies
  • Calcium Carbonate Crystallization and Inhibition
  • Natural Compounds in Disease Treatment
  • Immunotherapy and Immune Responses
  • Toxoplasma gondii Research Studies

Ministry of Agriculture and Rural Affairs
2019-2025

Chinese Academy of Fishery Sciences
2011-2025

Suzhou University of Science and Technology
2022-2024

Xianning Central Hospital
2023

Hubei University of Science and Technology
2023

Anhui University
2023

Chinese Academy of Sciences
2013-2016

Institute of Hydrobiology
2013-2016

First Affiliated Hospital of Kunming Medical University
2016

Kunming Medical University
2016

Abstract Sturgeons and paddlefishes (Acipenseriformes) occupy the basal position of ray-finned fishes, although they have cartilaginous skeletons as in Chondrichthyes. This evolutionary status their morphological specializations make them a research focus, but complex genomes (polyploidy presence microchromosomes) bring obstacles challenges to molecular studies. Here, we generated first high-quality genome assembly American paddlefish (Polyodon spathula) at chromosome level. Comparative...

10.1093/molbev/msaa326 article EN cc-by Molecular Biology and Evolution 2020-12-15

Background: Sturgeons (Chondrostei: Acipenseridae) are a group of "living fossil" fishes at basal position among Actinopteri. They have raised great public interest due to their special evolutionary position, species conservation challenges, as well highly-prized eggs (caviar). The sterlet, Acipenser ruthenus, is relatively small-sized member sturgeons and has been widely distributing in both Europe Asia. In this study, we performed whole genome sequencing, de novo assembly gene annotation...

10.3389/fgene.2019.00776 article EN cc-by Frontiers in Genetics 2019-09-05

PIWI proteins and Piwi‐interacting RNAs (piRNAs) are crucial for gametogenesis, embryogenesis, stem cell maintenance in animals. The Piwil1 ( Piwi-like RNA-mediated gene silencing 1 ) has rapidly evolved the protogynous hermaphrodite ricefield eel Monopterus albus compared to other teleosts. Notably, there is a significant reduction DNA methylation levels an increase expression of testes those ovaries. However, role gonadogenesis remains unclear. This study elucidated histomorphological...

10.1155/are/8161999 article EN cc-by Aquaculture Research 2025-01-01

The largefin longbarbel catfish (Hemibagrus macropterus), a freshwater species endemic to China with fundamental economic importance, requires investigation into its genetic structure for effective management. In this study, we employed mitochondrial cytochrome b (Cytb) gene sequences and 14 microsatellite loci elucidate the of 195 individuals across eight distinct populations. Cytb analysis revealed haplotype number (H) 31, diversity (Hd) 0.853, nucleotide (π) 0.0127. Population neutrality...

10.3390/ani15060770 article EN cc-by Animals 2025-03-08

Plasmodium falciparum resistance to artemisinin emerged in the Greater Mekong Sub-region has been associated with mutations propeller domain of kelch gene Pfk13. Here polymorphisms Pvk12 gene, orthologue Pfk13 vivax, were determined by PCR and sequencing 262 clinical isolates collected recent years (2012–2015) from China-Myanmar border area. Sequencing full-length genes these identified three synonymous (N172N, S360S, S697S) one non-synonymous mutation M124I, all which at very low prevalence...

10.1186/s12936-016-1592-z article EN cc-by Malaria Journal 2016-11-04

Currently, the effects of dietary levels n-3 highly unsaturated fatty acids (HUFAs) on growth performance, antioxidant capacity, immunity, and serum oxylipin profiles female F

10.3390/antiox13040421 article EN cc-by Antioxidants 2024-03-29

Abstract Little is known about the major histocompatibility complex (MHC) in genome of Yangtze finless porpoise ( Neophocaena asiaeorientalis ) (YFP) or other cetaceans. In this study, a high-quality YFP bacterial artificial chromosome (BAC) library was constructed. We then determined organization and characterization MHC class II region by screening BAC library, followed sequencing assembly positive clones. The consists two segregated contigs (218,725 bp 328,435 respectively) that include...

10.1038/srep22471 article EN cc-by Scientific Reports 2016-03-02

During the evolutionary transition from land to water, cetaceans have undergone numerous critical challenges, with osmoregulation being major one. Two subspecies of narrow-ridged finless porpoise (Neophocaena asiaeorientalis), freshwater Yangtze (N. a. asiaeorientalis, NAA) and marine East Asian sunameri, NAS), provide excellent subjects understand genetic basis osmoregulatory divergence between mammals. The kidney plays an important well-established role in mammals thus, herein, we utilized...

10.3390/ijms16012220 article EN International Journal of Molecular Sciences 2015-01-20

Ecological surveys have indicated that the population of critically endangered Yangtze finless porpoise (YFP, Neophocaena asiaeorientalis asiaeorientalis) is becoming increasingly small and fragmented, will be at high risk extinction in near future. Genetic conservation this an important component long-term effort. We used a 597 base pair mitochondrial DNA (mtDNA) control region 11 microsatellite loci to analyze genetic diversity structure YFP. The analysis both mtDNA suggested YFP possibly...

10.3390/ijms150711307 article EN International Journal of Molecular Sciences 2014-06-25

A 12-week feeding trial was conducted to determine the influence of dietary protein levels on growth performance, body composition, haematological parameters and digestive enzyme activity Chinese rice field eel (Monopterus albus) fingerlings. Six isolipidic experimental diets (27.89%, 32.23%, 35.95%, 40.06%, 43.31% 46.53%) were formulated randomly assign triplicate groups 50 fingerlings (5.0 ± 0.5 g) cultured in plastic cages. Results indicated that best performance fish with highest WG...

10.1111/are.14387 article EN Aquaculture Research 2019-11-25

Epigallocatechin-3-gallate (EGCG) has been recognized as a potential additive for aquafeeds due to its beneficial biological functions. In order evaluate the application of EGCG in Chinese rice field eel (Monopterus albus), six isonitrogenous and isolipidic diets containing 0, 25, 50, 100, 200, 400 mg/kg were formulated fed Monopterus albus (M. albus) 9 weeks. The results showed that M. 0 100 presented higher weight again specific growth rate than other groups. Fish with displayed lower...

10.1155/2023/6512136 article EN cc-by Aquaculture Nutrition 2023-11-17

In this study, six candidate female-specific DNA sequences of octaploid Amur sturgeon (Acipenser schrenckii) were identified using comparative genomic approaches with high-throughput sequencing data. Their specificity was confirmed by traditional PCR. Two these sex-specific also validated as in other eight species and two hybrid sturgeons. The fragments suggest that the family Acipenseridae has a ZZ/ZW sex-determining system. However, one been deleted some sturgeons such Sterlet ruthenus),...

10.1016/j.ygeno.2021.11.012 article EN cc-by-nc-nd Genomics 2021-11-01

10.1016/j.cbpb.2019.01.006 article EN Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology 2019-01-18

The Chinese longsnout catfish (Leiocassis longirostris) is an economically important freshwater fish in China; however, its wild resources have declined dramatically recent decades. Understanding the genetic structure of populations crucial to guide breeding programs and fishy restoration. In this study, 15 highly polymorphic microsatellite DNA loci were used evaluate diversity population structure. show high diversity; they do not significant differentiation or systematic geographic pattern...

10.3390/fishes9010035 article EN cc-by Fishes 2024-01-15

The ricefield eel (Monopterus albus), a protogynous hermaphroditic Synbranchiform species, is one of the most economically valuable freshwater fish in China. Studies on sexual change will contribute to artificial culture and understanding sex determination differentiation fish. In this study, whole-genome DNA methylation transcriptomes ovary testis were analysed eel. An elevated level genome was observed compared with ovary. A total 457 genes showed negative correlation between status...

10.1111/are.15457 article EN Aquaculture Research 2021-07-12

To study the effect of Ca/P ratio on P and Ca absorption excretion in hybrid sturgeon (Huso dauricus♀ X Acipenser schrenckii♂), five groups fish were intubated with 100 mg P·kg−1 BW ratios 0:1, 0.25:1, 0.5:1, 1:1, 2:1. Plasma concentrations significantly elevated at below 2:1, highest value was obtained 0.5:1. content increased ratio. Urine rate 0.5:1 higher than that 0:1 The urea rates observed 1:1. total 48 h post intubation reached about 30 mg·kg−1 BW, which recorded for group present...

10.3390/fishes7030138 article EN cc-by Fishes 2022-06-10

The largefin longbarbel catfish, Hemibagrus macropterus , is an economically important fish species in southwestern China, with males growing faster than females. This study presents a high-quality chromosome-level genome assembly of the generated by integrating Illumina short reads, PacBio HiFi long and Hi-C data. assembled size was 858.5 Mb, contig scaffold N50 5.8 Mb 28.4 respectively. A total 656 contigs were successfully anchored to 30 pseudochromosomes BUSCO score 97.7%, consistent...

10.3389/fgene.2023.1297119 article EN cc-by Frontiers in Genetics 2023-11-01
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