A5101855320- Reproductive Biology and Fertility
- Acupuncture Treatment Research Studies
- Music Therapy and Health
- Sperm and Testicular Function
- Organ Transplantation Techniques and Outcomes
- Gut microbiota and health
- Cardiac Ischemia and Reperfusion
- Cancer-related molecular mechanisms research
- Medical Research and Treatments
- RNA modifications and cancer
- Blood Pressure and Hypertension Studies
- Advanced oxidation water treatment
- Esophageal Cancer Research and Treatment
- Anesthesia and Neurotoxicity Research
- Lung Cancer Diagnosis and Treatment
- Reproductive Health and Technologies
- Tracheal and airway disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Retinal Diseases and Treatments
- Circular RNAs in diseases
- Gout, Hyperuricemia, Uric Acid
- Ovarian function and disorders
- Arsenic contamination and mitigation
- Acute Ischemic Stroke Management
Shandong First Medical University
2022-2025
Nantong University
2025
Zhangzhou Municipal Hospital of Fujian Province
2019-2024
Fujian Medical University
2019-2024
Sun Yat-sen University
2023-2024
Southwest University of Science and Technology
2024
Shanxi Province Hospital of Traditional Chinese Medicine
2022-2024
The First Affiliated Hospital, Sun Yat-sen University
2024
Nanjing University of Posts and Telecommunications
2024
Shanxi Academy of Medical Sciences
2015-2023
Metabolic Associated Steatotic Liver Disease (MASLD), encompassing conditions simple liver steatosis (MAFL) and metabolic associated steatohepatitis (MASH), is the most prevalent chronic disease. Currently, management of MASLD impeded by lack reliable diagnostic biomarkers effective therapeutic strategies. We analyzed eight independent clinical datasets from GEO database. Differential expression weighted gene co-expression network analyses (WGCNA) were used to identify 23 genes related...
Abstract Background Obstructive sleep apnea (OSA) is associated with increased risk of lung cancer mortality. Nevertheless, little known about the underlying molecular mechanisms. This research aimed to investigate differentially expressed genes (DEGs) and explore their function in Lewis carcinoma (LLC)-bearing mice exposed chronic intermittent hypoxia (CIH) by transcriptome sequencing. Methods Lung tissues LLC-bearing CIH or normoxia were subjected for sequencing examine DEGs. Gene Ontology...
Transcutaneous electrical acupoint stimulation (TEAS) is a form of acupuncture treatment that applies on specific through cutaneous electrodes. This technique has been used for perioperative anesthesia management as part after surgery recovery. However, to date, limited data are available using the TEAS postoperative recovery in elderly surgical patients. We conducted this prospective randomized sham-control trail evaluate efficacy group patients receiving knee under epidural anesthesia. 52...
Silicosis is a prevalent occupational disease marked by progressive pulmonary fibrosis. Despite its significant health burden, the pathogenesis of silicosis remains unclear, and no specific therapeutic drugs are available. In this study, we developed novel intervention strategy targeting gut microbiota investigated underlying mechanisms. Using 16S rRNA gene sequencing, observed dysbiosis in rats at different times (1-8 weeks), notably characterized altered relative abundance Ruminococcus...
Abstract Background Weedy rice competes for nutrients and living space with cultivated rice, which results in serious reductions production. The rhizosphere bacterial community plays an important role nutrient competition between species. It is therefore to clarify the differences diversities of inter weedy rice. compositions co-occurrence networks are largely unknown thus aim our study. Results In study, different structures (AW), (AY) surrounded by (WY) were determined based on 16S rRNA...
Abstract Background To investigate the value of endobronchial ultrasound (EBUS) and virtual bronchoscopic navigation (VBN) combined with rapid on-site evaluation (ROSE) in diagnosing peripheral pulmonary lesions (PPLs). Methods Between January 1st 2019 to September 2021, EBUS VBN examination were performed expected consecutive patients PPLs who admitted Zhangzhou Affiliated Hospital Fujian Medical University (Fujian, China). Finally, based on calculation diagnostic yield R-EBUS biopsy drop...
As the main solid waste of wastewater treatment plants (WWTPs), sewage sludge has characteristics large output and high contents organic matter inorganic metals. In this study, was used as raw material to prepare a unique sludge-based biochar. order obtain best modification method for ammonium phosphorus adsorption removal in wastewater, biochar modified by loading four kinds metal, respectively, including Mg, Al, Fe, Mn, improve capacity A number experiments showed that Mg-modified...
Introduction: This study aims to investigate the function and potential mechanism of Tanshinone IIA in uric acid-induced HK-2 fibrosis models Materials Methods: An vitro model was constructed using acid stimulation. RT-qPCR Western blot were used evaluate levels inflammatory cytokines. The detection ROS ELISA assay analyze changes oxidative stress. Results: inhibited increase cytokines TNF-α, IL-1β, IL-6, IL-18 formation NLRP3 inflammasome induced by In addition, treatment reduced production...
Abstract This study proposed a novel advanced oxidation system to treat metal and antibiotic pollution in water simultaneously. Meanwhile, the enhancement effect of absorbed on activation persulfate was also investigated. As most widely used polluting material, tetracycline (TC) Fe were as pollutant models. In this study, carbonaceous material (BC) prepared from excess sludge then combined with (Fe/BC/PS). It found that best biochar obtained when pyrolysis temperature reached 500 °C (BC500),...
Objective: To investigate the effectiveness of intense pulsed light (M22) in treating patients with meibomian gland dysfunction (MGD) caused by demodex mites. Methods: A total 100 (100 eyes) diagnosed mites through microscopic examination at Shanxi Bethune Eye Clinic between June 2021 and May 2023 were selected using convenience sampling. The randomly divided into two groups: an experimental group (n=50) a control (n=50). received comprehensive treatment consisting artificial tears, warm...
Postoperative cognitive dysfunction (POCD) is one of the major complications in patients who have undergone surgeries. Reduction surgery-induced inflammation and perioperative stress responses may prevent development POCD. As recent experimental data suggested, Shenmai Shenfu injections, two ginseng containing formulations, improve cognition. We designed this study using aged rats as an model to determine effect combined injection preventing POCD exploring underlying mechanism intervention....
The regulatory network of competing endogenous RNAs (ceRNA) exists widely in tumors and affects the expression cancer-related genes, thus playing an important role development prognosis human tumors. In this research, we explored mechanism LINC00665 as a ceRNA breast cancer. We analyzed targets cancer using bioinformatics, detected their effects on cells by CCK8, transwell, colony formation flow cytometry assays. From our results, knockdown suppressed proliferation, migration invasion...
The recurrence of Ischemic cerebrovascular events (ICE) often results in a high rate mortality and disability. However, due to the lack labeled follow-up data hospitals, prediction methods using traditional machine learning are usually not available or reliable. Therefore, we propose new framework for predicting long-term risk patients with ICE after discharge from hospitals based on process mining transfer learning, point out high-risk intervention. First, models discovered clinical...
Recent advancements in single-cell genomics necessitate precision gene panel selection to interpret complex biological data effectively. Those methods aim streamline the analysis of scRNA-seq by focusing on most informative genes that contribute significantly specific task. Traditional methods, which often rely expert domain knowledge, embedded machine learning models, or heuristic-based iterative optimization, are prone biases and inefficiencies may obscure critical genomic signals....
Abstract This study explores the effects of apelin on retinal microglial cells in rat models oxygen‐induced retinopathy prematurity (ROP). Totally, 274 rats were selected for establishing (OIR) models, and 92 healthy control group. OIR assigned into OIR, 10 −5 g/L apelin, −4 −3 groups. Immunohistochemistry was employed to determine morphology cell number. CDllb, ionized calcium‐binding adapter molecule 1 (IBA‐1), TNF‐α, iNOS mRNA protein expressions identified using RT‐qPCR Western blotting,...
Abstract Background: C-arm-based flat-panel detector cone-beam computed tomography (CBCT) venography has never been used in the management of iliac vein compression syndrome (IVCS). This study aimed to determine technical feasibility and safety CBCT diagnosis IVCS compared with conventional (CV). Methods: Twenty patients clinical manifestations lower extremity venous insufficiency were prospectively enrolled between May 2018 December 2018. Each patient underwent both CV venography. The...
Type 2 mellitus (T2DM), a chronic metabolic disorder, causes severe impairment of patients' quality life and has attracted global attention. Many studies have suggested the importance gut microbiota in occurrence T2DM. The Scrophulariae Radix Atractylodes sinensis (XC) pair, recommended traditional Chinese medicine (TCM), been used for treating diabetes many years. However, research on role XC pair modulating microbial communities is lacking, but it important to elucidate underlying...