Zhiwei Zhao

ORCID: 0009-0007-0974-7628
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Research Areas
  • Obstructive Sleep Apnea Research
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Tracheal and airway disorders
  • Anorectal Disease Treatments and Outcomes
  • Pelvic and Acetabular Injuries
  • Pelvic floor disorders treatments
  • Receptor Mechanisms and Signaling
  • Atherosclerosis and Cardiovascular Diseases
  • Esophageal Cancer Research and Treatment
  • Neuropeptides and Animal Physiology
  • Lipoproteins and Cardiovascular Health
  • Liver Disease Diagnosis and Treatment
  • Cardiac electrophysiology and arrhythmias
  • Coronary Interventions and Diagnostics
  • Lung Cancer Diagnosis and Treatment
  • Morinda citrifolia extract uses
  • Stress Responses and Cortisol
  • Cancer Cells and Metastasis
  • Pancreatitis Pathology and Treatment
  • Traditional Chinese Medicine Analysis
  • Cancer Risks and Factors
  • Mathematical and Theoretical Epidemiology and Ecology Models
  • Cancer, Stress, Anesthesia, and Immune Response
  • COVID-19 epidemiological studies
  • ECG Monitoring and Analysis

West China Medical Center of Sichuan University
2017-2025

Beijing Tongren Hospital
2025

Zhangzhou Municipal Hospital of Fujian Province
2021-2024

Fujian Medical University
2021-2024

Guangdong Ocean University
2024

Xianning Central Hospital
2024

Hubei University of Science and Technology
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2024

Wuhan Hankou Hospital
2023

University of Science and Technology of China
2017-2022

Efficient and durable oxygen evolution reaction (OER) catalysts are highly required for the cost-effective generation of clean energy from water splitting. For first time, an integrated OER electrode based on one-step direct growth metallic iron-nickel sulfide nanosheets FeNi alloy foils (denoted as FeNi3 S2 /FeNi) is reported, origin enhanced activity uncovered in combination with theoretical experimental studies. The obtained /FeNi exhibits catalytic long-term stability toward strong...

10.1002/smll.201604161 article EN Small 2017-03-10

Male and female hearts have many structural functional differences. Here, we investigated the role of estrogen (E2) in mechanisms sex differences contraction through cAMP-L-type Ca2+channel pathway adult mice left ventricular (LV) apical myocytes at basal stress state. Isolated LV from male, (Sham) ovariectomised (OVX) were used to investigate contractility, Ca2+ transients L-type channel (LTCC) function. The levels β2AR, intracellular cAMP, phosphodiesterase (PDE 3 PDE 4), RyR2, PLB, SLN,...

10.1186/s12964-019-0346-2 article EN cc-by Cell Communication and Signaling 2019-04-15

Introduction In the pathology of pelvic organ prolapse (POP), little is known about contributing role microenvironment. Also, age-related differences in microenvironment POP patients always ignored. present study, we investigated between Young and Old patients, novel cell types critical regulators which contributes to differences. Methods Single-cell transcriptomic analyses were used detect changes composition gene expression from control group (<60 years), years) (>60 years)....

10.3389/fimmu.2023.1084516 article EN cc-by Frontiers in Immunology 2023-02-20

Epithelial-mesenchymal transition (EMT) is a biological process that associated with cancer metastasis and invasion. In cancer, EMT promotes cell motility, invasion distant metastasis. Interleukin (IL)-8 highly expressed in tumors may induce EMT. The IL-8/IL-8R axis has vital role carcinoma, which regulated by several signaling pathways, including the transforming growth factor β-spleen tyrosine kinase/Src-AKT/extracellular signal-regulated kinase, p38/Jun N-terminal kinase-activating...

10.3892/ol.2017.6034 article EN Oncology Letters 2017-04-13

Currently, there are no conventional treatments for stress-induced cardiomyopathy (SCM, also known as Takotsubo syndrome), and the existing therapies not effective. The recently discovered G protein-coupled estrogen receptor (GPER) executes rapid effects of (E2). In this study, we investigated mechanism GPER on epinephrine (Epi)-induced cardiac stress. SCM was developed with a high dose Epi in adult rats human-induced pluripotent stem cells-derived cardiomyocytes (hiPSC-CMs). (1) activation...

10.1530/joe-20-0451 article EN Journal of Endocrinology 2021-04-13

In recent years, depression has become a global public health concern, and one of the common concomitant symptoms are diminished sexual motivation impaired performance. The aim this study was to investigate potential effects Morinda officinalis oligosaccharides (MOO) on its symptom, dysfunction. Chronic unpredictable mild stress (CUMS)-induced model constructed, MOO abilities were evaluated. results revealed that able alleviate CUMS-induced depression-like behavior in mice, inhibit...

10.3389/fnins.2024.1509543 article EN cc-by Frontiers in Neuroscience 2025-01-08

Abstract Background To investigate the value of endobronchial ultrasound (EBUS) and virtual bronchoscopic navigation (VBN) combined with rapid on-site evaluation (ROSE) in diagnosing peripheral pulmonary lesions (PPLs). Methods Between January 1st 2019 to September 2021, EBUS VBN examination were performed expected consecutive patients PPLs who admitted Zhangzhou Affiliated Hospital Fujian Medical University (Fujian, China). Finally, based on calculation diagnostic yield R-EBUS biopsy drop...

10.1186/s12890-022-01917-z article EN cc-by BMC Pulmonary Medicine 2022-03-31

The rate of saphenous vein graft failure one year after coronary artery bypass grafting ranges from 10% to 25%. aim this study was explore whether atorvastatin can reduce accumulation vascular smooth muscle cells inhibit intimal hyperplasia via p38 MAPK pathway inhibition.Forty-five Sprague-Dawley rats were randomized three groups. Thirty received a operation, and they be treated with vehicle or atorvastatin; fifteen sham operation. We detected by hematoxylin-eosin staining related protein...

10.36660/abc.20190231 article EN cc-by-nc Arquivos Brasileiros de Cardiologia 2020-10-01

Purpose: Vitamin D deficiency was thought to be associated with insulin resistance and metabolic-associated fatty liver disease (MAFLD). The aim of this study investigate the relationship between triglyceride-glucose (TyG) index, a useful surrogate biomarker resistance, vitamin status in patients MAFLD. Patients Methods: A total 566 MAFLD were included retrospective cross-sectional study. Clinical characteristics compared participants without deficiency. association TyG index serum...

10.2147/dmso.s421840 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2023-08-01

Objective: To investigated whether CBS3830, a highly selectively inhibitor of p38MAPK, could ameliorate inflammation and intimal hyperplasia in arterialized vein grafts (AVGs).Methods: Sixty male Sprague-Dawley rats underwent reversed right jugular to common carotid artery interposition graft were randomly treatment with vehicle (control) or single-dose (3 mg/kg, preoperative) double-dose preoperative 4 d postoperative) CBS3830. Twenty sham operation. The levels tumor necrosis factor-α...

10.3109/08923973.2014.956754 article EN Immunopharmacology and Immunotoxicology 2014-09-10

Atrial fibrillation (AF) is reportedly a risk factor for cognitive impairment. Interestingly, recent studies have emphasized that impaired cognition probably an initiating of cardiovascular disease. Thus, we aimed to explore the association between and AF, clarify potential mechanisms.

10.5603/cj.93107 article EN cc-by-nc-nd Cardiology Journal 2024-08-29

Liver fibrosis is a critical factor in the advancement of nonalcoholic fatty liver disease towards cirrhosis. There limited research exploring association between obstructive sleep apnea (OSA) and among community populations. The present study aimed to assess (SA) based on National Health Nutrition Examination Survey (NHANES). Data were acquired from NHANES survey cycle 2017 2020. We assessed by median values stiffness measurement (LSM). diagnosis SA was participants' response questionnaire....

10.1097/md.0000000000037949 article EN cc-by-nc Medicine 2024-04-26

Wilson disease is an autosomal recessive genetic found by Samuel Alexander Kinnier and prevalent in childhood adolescents.

10.1097/md.0000000000040018 article EN cc-by-nc Medicine 2024-10-18

Considering the two measures of vaccination to susceptible population and isolation treatment infectious population, this study builds a SEIQR -V disease model with incubation period, which is based on principle cellular automata. According random walking principle, it gets an expanded Moore neighbor. For influenza A (H1N1), BP neural network used recognize quarantine intensity parameters some countries. Furthermore, according Cellular Automata’s simulation number infections under different...

10.28919/cmbn/2166 article EN Communications in Mathematical Biology and Neuroscience 2015-04-12
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