- Mesenchymal stem cell research
- Immune cells in cancer
- Reproductive System and Pregnancy
- Immune Response and Inflammation
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- IL-33, ST2, and ILC Pathways
- Cancer Cells and Metastasis
- Immunotherapy and Immune Responses
- Cholesterol and Lipid Metabolism
- Immune Cell Function and Interaction
- Maternal and fetal healthcare
- Pregnancy and Medication Impact
- Cancer, Stress, Anesthesia, and Immune Response
- CAR-T cell therapy research
- COVID-19 Impact on Reproduction
- PARP inhibition in cancer therapy
- Autoimmune Bullous Skin Diseases
- Toxin Mechanisms and Immunotoxins
- Respiratory viral infections research
- Diet and metabolism studies
- Eicosanoids and Hypertension Pharmacology
- Oral health in cancer treatment
- Cytokine Signaling Pathways and Interactions
- Rheumatoid Arthritis Research and Therapies
Ege University
2014-2021
Sivas State Hospital
2015-2021
The efficacy of complete blood count parameters in the diagnosis tubal
To determine role of human leukocyte antigen (HLA)-G, CD8, CD16, CD56, interferon (IFN)-γ, and tumor necrosis factor (TNF)-α for recurrent miscarriages in feto-maternal interface.Chorion decidua samples were obtained from 11 women with unwanted pregnancies (healthy pregnancy, HP) 10 missed abortion diagnosis after at least two pregnancy losses (recurrent miscarriage, RM). In addition, endometrial tissues non-pregnant (NonP). The expressions markers evaluated using the Western blot analysis....
Aim: Mesenchymal stem cells (MSCs) are strong immunomodulatory and a component of the tumor microenvironment. In this study, we aimed to investigate effects MSCs derived from adipose tissue on expressions immune evasive molecules indoleamine 2,3-dioxygenase (IDO), human leukocyte antigen G (HLA-G) programmed death-ligand 1 (PD-L1) breast cell lines MDA-MB-231 MCF-7. Methods: For purpose, MSCs, MCF-7 were cultured with increased doses interferon gamma (IFN-g). another plate, in transwell...
Objective: The aim of this study is investigation effect glycemic control on the levels malondialdehyde-low-density-lipoprotein-immunglobulin G (MDA-LDL-IgG) which supposed to be positively correlated with myocardial infarction risk in subjects type 2 diabetes mellitus (DM). Material and Method: We evaluated glucose, triglyceride, total cholesterol, high-density-lipoprotein-cholesterol (HDL-C), low-density-lipoprotein-cholesterol (LDL-C), hemoglobin A1c (A1C) MDA-LDL-IgG...
Carotid intima-media thickness in postmenopausal women is associated with an endometrial greater than 5 mm Grubość błony środkowej i wewnętrznej tętnicy szyjnej u kobiet po menopauzie jest związana z grubością endometrium większą niż 5mm)DWPD (VNLFLR÷OXï 0XKDPPHW 6DNÕS (VNLFLR÷OXð $OSHU 7XQJD g]GHPLU %H\KDQ g]\XUW
The effects of preconditioning with IFN-γ, IL-4, and IL-10 on costimulatory ligand expressions mesenchymal stem cells M esenchymal (MSCs) are powerful immunomodulatory cells.Molecules such as prostaglandin E2 (PGE2), indoleamine-pyrrole 2,3-dioxygenase (IDO), transforming growth factor-beta (TGF-β), interleukin (IL) 10, hepatocyte factor (HGF) play an important role in the formation these [1-3].Molecules cell surface MSCs another mechanism that suppresses immune through contact.Strong...
Objectives: In this study, it was aimed to investigate the immunomodulatory effects of Mesenchymal stem cells (MSCs) on Natural Killer (NK) activated by Toll-like receptor (TLR) agonists. Methods: MDA-MB-231, MCF-7 and NK-92 were induced with TLR3, TLR7/8 TLR9 agonists co-cultured MSCs. Alterations in IFN-?, TNF-?, Granzyme-b Perforin expressions determined qPCR method, CD69 CD107a flow cytometry, cytotoxicity MTT-assay. Results: All TLR significantly increased Granzyme-b, Perforin,...
Objective: The aim of this study is investigation effect glycemic control on the levels malondialdehyde-low-density-lipoprotein-immunglobulin G (MDA-LDL-IgG) which supposed to be positively correlated with myocardial infarction risk in subjects type 2 diabetes mellitus (DM). Material and Method: We evaluated glucose, triglyceride, total cholesterol, high-density-lipoprotein-cholesterol (HDL-C), low-density-lipoprotein-cholesterol (LDL-C), hemoglobin A1c (A1C) MDA-LDL-IgG well-controlled DM...