A5075329063- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Immunodeficiency and Autoimmune Disorders
- Respiratory and Cough-Related Research
- Mesenchymal stem cell research
- Immunotherapy and Immune Responses
- Pharmaceutical studies and practices
- Autoimmune Bullous Skin Diseases
- IL-33, ST2, and ILC Pathways
- Contact Dermatitis and Allergies
- Immune Cell Function and Interaction
- Nasal Surgery and Airway Studies
- Olfactory and Sensory Function Studies
- Immune cells in cancer
- Tuberculosis Research and Epidemiology
- Eosinophilic Disorders and Syndromes
- Cancer Cells and Metastasis
- Islamic Thought and Society Studies
- Obsessive-Compulsive Spectrum Disorders
- Mast cells and histamine
- Chemotherapy-related skin toxicity
Manisa Celal Bayar University
2013-2025
ENT and Allergy
2011
Ege University
1998
Background . We aimed in our study to research the role of new cytokines such as IL-35, IL-22, and IL-17 that may form a target for novel treatment approaches. Methods IL-10, IL-17, TGF- β , IFN- γ IL-35 serum levels allergic rhinitis (AR) patients were measured using ELISA method. Allergic sensitization was demonstrated by skin prick test. Patients only with olive tree sensitivity evaluated seasonal AR (SAR). mite included perennial (PAR). clinic severity nasal symptom scores (NSS). Results...
<i>Background:</i> Allergic rhinitis (AR) is a disease in which T-helper (Th)2 response predominant and its pathogenic mechanism still poorly understood. <i>Aim:</i> To evaluate the possible role of Th1, Th2 regulatory-T (Treg) cells pathogenesis AR. <i>Methods:</i> This case-control study enrolled 41 patients with seasonal AR (10–62 years old), sensitive to olive pollens, 15 healthy controls (18–60 old). Nasal biopsy was performed specimens nasal lavage...
Background: The aim of MASK-air® application is to enhance awareness allergic rhinitis (AR) and its complications, thereby reducing the risk developing asthma. Objective: aims this study were evaluate impact on quality life (QoL) symptomatology AR patients undergoing allergen immunotherapy (AIT). also evaluated patient satisfaction with application. Materials Methods: A prospective cross-sectional was conducted between August November 2019 at a tertiary Allergy Immunology center involving...
Osteoporosis that is encountered frequently in postmenopausal women, may cause an increased incidence of vertebral and iliac fractures are associated with excess morbidity. Raloxifene hydrochloride, a selective oestrogen receptor modulator, has been shown to increase bone mineral density decrease biochemical markers turnover without stimulatory effects on breast or uterus. Levels proinflammatory cytokines, including IL-6, TNF-alpha TGF-beta1 which important cytokines involved remodeling,...
<b><i>Background:</i></b> Omalizumab has demonstrated therapeutic benefits both in controlled clinical trials and real-life studies. However, research concerning the long-term effects tolerability of omalizumab is needed. The main objective this study was to evaluate effectiveness treatment with for up 5 years. <b><i>Methods:</i></b> A multicenter, retrospective, chart-based carried out compare documented exacerbations, hospitalizations,...
Autoimmune thyroid diseases are the most common of all autoimmune diseases. In literature, Hashimoto thyroiditis (HT) is considered to be a T-helper (Th) type 1 dominant condition, and Graves disease Th2-dominant condition.The aim this study was highlight new aspect relationships among Th cell subgroups by determining incidence in patients with allergic rhinitis (AR).Patients were diagnosed AR based on their medical histories, physical examinations, skin-prick test results an outpatient...
Seasonal allergic rhinitis (SAR) is characterized by a helper T (Th)2 cell-mediated immune response at the target site. There relative Th1 and/or regulatory (Treg) cell insufficiency in patients with SAR. It has been demonstrated that there change balance between these cells after allergen-specific immunotherapy (SIT), which curative treatment modality for this disease. However, are few studies evaluate number and function of inflammatory area SIT treatment. We aimed to investigate...
To contribute to the understanding of pathogenesis chronic spontaneous urticaria (CSU) by identifying its relationship with autoimmunity and cytokines using autologous serum skin test (ASST) peripheral blood mononuclear cell culture (PBMC) method.Interleukins (IL)-4, IL-10, transforming growth factor (TGF-β1), interferon (IFN)-γ, IL-17A, IL-23 levels in supernatants obtained PBMC method were measured ELISA. Disease activity was assessed determining score (UAS).A total 40 patients diagnosed...
Summary Background There is a difference in the extent of remodelling allergic rhinitis (AR) and asthma. This may be attributed to local tissue response these mediators. Objectives The aim this study was compare vascular endothelial growth factor (VEGF) its receptor foetal liver kinase (Flk)‐1 expression between seasonal AR patients with or without asthma non‐allergic controls as well that Methods Thirteen subjects six were included study. Allergic sensitization demonstrated by skin prick...
Hashimoto's thyroiditis is a chronic, organ-specific autoimmune disease. It the most common cause of primary hypothyroidism during adolescent period, via thyroid tissue destruction, affecting 2% population. The pathogenesis involves complex interaction between predisposing genetic and environmental factors. In this study, we wanted to investigate role cytokines such as IL-2, IL-4, IL-12 IFN-gamma in disease, changes cytokine levels brought about by treatment with L-thyroxine. Sixty five...