A5101498643- Marine Biology and Ecology Research
- Ichthyology and Marine Biology
- Cephalopods and Marine Biology
- Marine animal studies overview
- Marine Ecology and Invasive Species
- Aquatic Invertebrate Ecology and Behavior
- Regulation of Appetite and Obesity
- Mollusks and Parasites Studies
- Insect and Arachnid Ecology and Behavior
- Plant and animal studies
- RNA modifications and cancer
- Neurobiology and Insect Physiology Research
- Crustacean biology and ecology
- Marine Biology and Environmental Chemistry
- Parasite Biology and Host Interactions
- Underwater Acoustics Research
- RNA Research and Splicing
- Marine and coastal plant biology
- Marine Invertebrate Physiology and Ecology
- Cancer-related gene regulation
- Hearing, Cochlea, Tinnitus, Genetics
- Fish Biology and Ecology Studies
- Diptera species taxonomy and behavior
- Genetic Neurodegenerative Diseases
- Coral and Marine Ecosystems Studies
Ludwig-Maximilians-Universität München
2015-2025
Central European Institute of Technology
2022
Masaryk University
2022
Central European Institute of Technology – Masaryk University
2022
Max Planck Institute for Metabolism Research
2013-2020
University of Cologne
2013-2019
Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases
2013-2019
University Hospital Cologne
2013-2019
Bayerische Staatssammlung für Paläontologie und Geologie
2016
Max Planck Institute of Biochemistry
2013
Polymorphisms in the fat mass and obesity-associated gene (FTO) are associated with human obesity obesity-prone behaviors, including increased food intake a preference for energy-dense foods. FTO demethylates N6-methyladenosine, potential regulatory RNA modification, but mechanisms by which predisposes humans to remain unclear. In adiposity-matched, normal-weight humans, we showed that subjects homozygous "obesity-risk" rs9939609 A allele have dysregulated circulating levels of orexigenic...
Fluorescence is widespread in marine organisms but uncommon terrestrial tetrapods. We here show that many chameleon species have bony tubercles protruding from the skull are visible through their scales, and fluoresce under UV light. Tubercles arising bones of displace all dermal layers other than a thin, transparent layer epidermis, creating 'window' onto bone. In genus Calumma, number these sexually dimorphic most species, suggesting signalling role, also strongly reflects groups,...
Abstract By providing two examples, the option for embedding 3D models in electronic versions of life science publications is presented. These presumably representing first such published, are developmental stages an evertebrate ( Patella caerulea, Mollusca) and a vertebrate species Psetta maxima , Teleostei) obtained from histological section series reconstruction processed with software package Amira. surface rendering particularly suitable PDF file because they can easily be transformed...
Abstract Axons of globular bushy cells in the cochlear nucleus convey hyper‐accurate signals to superior olivary complex, initial site binaural processing via comparably thick axons and calyx Held synapse. Bushy cell fibers involved low‐frequency sounds are known have an unusual internode length‐to‐axon caliber ratio ( L / d ) correlating with higher conduction velocity temporal precision action potentials. How ‐ratio develops what determines this myelination pattern is unclear. Here we...
Adaptive myelination is the emerging concept of tuning axonal conduction velocity to activity within specific neural circuits over time. Sound processing exhibit structural and functional specifications process signals with microsecond precision: a time scale that amenable adjustment in length thickness myelin. Increasing auditory axons by introducing sound-evoked responses during postnatal development enhances myelin thickness, while sensory deprivation prevents such radial growth...
Abstract Biofluorescence is widespread in the natural world, but only recently discovered terrestrial vertebrates. Here, we report on discovery of iridophore-based, neon-green flourescence gecko Pachydactylus rangei , localised to skin around eyes and along flanks. The maximum emission fluorescence at a wavelength 516 nm green spectrum (excitation 465 nm, blue) with another, smaller peak 430 nm. fluorescent regions show large numbers iridophores, which are lacking non-fluorescent parts. Two...
Muscles undergo developmental transitions in gene expression and alternative splicing that are necessary to refine sarcomere structure contractility. CUG-BP ETR-3-like (CELF) family RNA-binding proteins important regulators of RNA processing during myogenesis misregulated diseases such as Myotonic Dystrophy Type I (DM1). Here, we report a conserved function for Bruno 1 (Bru1, Arrest), CELF1/2 homolog Drosophila , early muscle myogenesis. Loss Bru1 flight muscles results disorganization the...
In most modern bony fishes (teleosts) hearing improvement is often correlated with a close morphological relationship between the swim bladder or other gas-filled cavities and saccule more rarely utricle. A connection of an accessory structure to third end organ, lagena, has not yet been reported. recent study in Asian cichlid Etroplus maculatus provided first evidence that may come lagena. Our was designed uncover bladder-inner ear this species. We used new approach by applying combination...
Chitons (Polyplacophora) are molluscs considered to have a simple nervous system without cephalisation. The position of the class within Mollusca is topic extensive debate and neuroanatomical characters can provide new sources phylogenetic data as well insights into fundamental biology organisms. We report discrete anterior sensory structure in chitons, occurring throughout Lepidopleurida, order living chitons that retains plesiomorphic characteristics. novel “Schwabe organ” clearly visible...
Despite the diversity in fish auditory structures, it remains elusive how otolith morphology and swim bladder-inner ear (= otophysic) connections affect motion inner stimulation. A recent study visualized sound-induced motion; but tank acoustics revealed a complex mixture of sound pressure particle motion. To separate motion, we constructed transparent standing wave tube-like equipped with an inertial shaker at each end while using X-ray phase contrast imaging. Driving shakers resulted...
Abstract In many plant species, exposure to a changing environmental temperature regime induces an acclimation response that ultimately increases thermotolerance. Under elevated temperature, membrane systems undergo remodeling counteract destabilizing thermodynamic effects. Elevated also affects photosynthesis and carbohydrate metabolism due altered protein functions, enzyme activities, transport across systems. Here, combination of electrolyte leakage assays chlorophyll fluorescence...
Abstract Background Block-face scanning electron microscopy has opened a new era of connectomics research, in which it is possible to make dense reconstructions all cells clipping neuronal network, such as the retina, resolving synaptic contacts. Anchovies, exceptionally abundant marine teleosts, have retinae with regions for triple cone-based color vision and region specialized cone photoreceptors, so-called polycones, made long short cones axially oriented outer segment lamellae...
The helicoid microgastropod genera Leptogyra, Xyleptogyra and Leptogyropsis from deep, sunken wood off New Zealand, were originally classified among the poorly defined Skeneidae (Vetigastropoda, Trochoidea) based on shell characters, external morphology fine-structure of radulae. We investigated microanatomy histology several representatives by means serial semi-thin sectioning followed computer-aided 3D-reconstruction, studied structure, performed phylogenetic analyses histone (H3)...
Mesopsammic acochlidians are small, and organ complexity may be strongly reduced (regressive evolution by progenesis), especially in microhedylacean species. The marine interstitial hedylopsacean Pseudunela cornuta (Challis, 1970), however, was suggested as having a complex reproductive system resembling that of much larger, limnic benthic present study aims to reconstruct the detailed anatomy true P. from serial, semithin histological sections using modern computer-based 3D visualization...