- Virus-based gene therapy research
- Animal Virus Infections Studies
- Pressure Ulcer Prevention and Management
- Viral Infectious Diseases and Gene Expression in Insects
- Wound Healing and Treatments
- HIV Research and Treatment
- Mosquito-borne diseases and control
- Diabetic Foot Ulcer Assessment and Management
- T-cell and Retrovirus Studies
- Diagnosis and Treatment of Venous Diseases
- Viral Infections and Vectors
- Animal Disease Management and Epidemiology
- Virology and Viral Diseases
- Viral gastroenteritis research and epidemiology
- Monoclonal and Polyclonal Antibodies Research
- Herpesvirus Infections and Treatments
- Vector-borne infectious diseases
- Viral Infections and Immunology Research
- Retinal and Macular Surgery
- interferon and immune responses
- Surgical site infection prevention
- Fish Ecology and Management Studies
- Interprofessional Education and Collaboration
- Bacteriophages and microbial interactions
- Epilepsy research and treatment
University of Huddersfield
2016-2025
Royal London Hospital
2024
Pacific Northwest National Laboratory
2010-2022
Swinburne University of Technology
2017-2022
Calderdale and Huddersfield NHS Foundation Trust
2022
Australian Catholic University
2015-2022
University of Sheffield
2022
Örebro University
2022
Ghent University
2022
National Health and Medical Research Council
2022
A culture method has been developed in which erythroid colonies are produced vitro from hemopoietic cells the livers of 13-day fetuses C3H(f)/Bi mice. Heme synthesis by cultures was correlated with presence these colonies, and hemoglobin shown to be electrophoretically normal. The individual were identified as since they erythropoietin-dependent, positively stained histochemical "Lepehne" procedure for hemoglobin, labeled (59)Fe radioautography. Evidence is presented that development under...
We have molecularly cloned a unique acutely transforming replication-defective mouse type C virus (3611-MSV) and characterized its acquired oncogene. The viral genome closely resembles Moloney (M) murine leukemia (MuLV), except for substitution in M-MuLV the middle of p30 polymerase gene (pol). Heteroduplex analysis revealed that 2.4 kilobases DNA were replaced by 1.2 cellular DNA. junctions between sequences determined sequence to be 517 nucleotides into 1,920 sequence. Comparison from...
Transforming growth factors (TGFs) were purified from serum-free medium conditioned by retrovirus-transformed Fisher rat embryo fibroblasts, mouse 3T3 cells, and two human melanoma cell lines. The purification of each TGF was monitored in a radioreceptor assay based on receptor crossreactivity with submaxillary gland epidermal factor (mEGF) achieved gel permeation chromatography the acid-soluble TGF-containing activity, followed reverse-phase high-pressure liquid sequential use acetonitrile...
In part I of this paper, exact expressions were obtained for the partition function and thermodynamic properties an $m\ifmmode\times\else\texttimes\fi{}n$ plane square lattice filled with $\frac{1}{2}\mathrm{mn}$ rigid dimers each occupying two adjacent sites. correlation model are studied aid a general perturbation theory Pfaffians. Closed formulas derived changes in probability dimer given bond that induced by proximity edge or corner lattic (singlet correlations) and, center fixed...
Graham, Brent MD, MSc, FRCSC; Peljovich, Allan E. MPH; Afra, Robert MD; Cho, Mickey S. Gray, Rob Stephenson, John Gurman, Andrew MacDermid, Joy PhD; Mlady, Gary Patel, Atul T. Rempel, David Rozental, Tamara D. Salajegheh, Mohammad Kian Keith, Michael Warren Jevsevar, MBA; Shea, Kevin G. Bozic, J. Adams, Julie Evans, Jay Mark Lubahn, Ray, Wilson Zachary Spinner, Thomson, Grant MSc; Shaffer, William O. Cummins, Deborah Murray, Jayson N. MA; Mohiuddin, Mukarram Mullen, Kyle Shores, Peter...
The relationship between obesity and health-related quality of life (HRQoL) may be confounded by factors such as multimorbidity. aim the study was to explore this relationship, controlling for long-term conditions other health, lifestyle demographic in a general adult population. There specific interest impact high weight status, measured body mass index (BMI) levels (obesity, morbid obesity) compared with individuals normal weight.Health, data were collected from 64,631 aged 16 years over...
Twenty-two displaced intra-articular fractures of the calcaneus (in twenty-two patients) were treated by open reduction and internal fixation with a screw one or two staples using lateral and, when needed, medial approach, followed early motion. Despite motion, nearly normal anatomical was achieved maintained in nineteen feet. After follow-up that ranged duration from sixteen to seventy-two months, clinical radiographic result rated as good seventeen patients fair one, there four failures....
Transmission electron microscopy was used to examine the microvasculature of perfusion-fixed tissues from Crohn's disease and control patients. Paramyxovirus-like particles, inclusions consisting condensations nucleocapsid, in giant cells endothelium at foci vascular injury were identified all 9 Tissues patients with also examined by either situ hybridisation (n = 10) or immunohistochemistry 15), compared inflammatory noninflammatory controls 22). Hybridisation for measles virus N-protein...
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Two genetic loci for induction of RNA C-type virus in BALB/c mouse embryo cells segregate independently backcross cell lines. The viruses at these are shown to be biologically distinguishable. first, described previously, codes activation a that grows preferentially NIH Swiss cells. newly detected locus poorly, if all, or cells, but replicates well rat line. Its serologic properties different from those the two major subgroups murine leukemia virus. present findings provide support...
Fujinami sarcoma virus (FSV) of chickens does not contain nucleotide sequences related to the src gene Rous virus, but it carries unique at least 3000 bases, which are likely code for transforming protein this virus. Using radioactive DNA complementary FSV-unique sequences, we investigated relatedness FSV other sarcoma-leukemia retroviruses in vertebrates. Under conditions moderate stringency, no cross-hybridization was detected between cDNA and RNAs Y73 avian several representative acute...