A5077013054- Acupuncture Treatment Research Studies
- Healthcare and Venom Research
- Veterinary Equine Medical Research
- Stress Responses and Cortisol
- Human-Animal Interaction Studies
- Neuroendocrine regulation and behavior
- Pain Mechanisms and Treatments
- Veterinary Orthopedics and Neurology
- Renin-Angiotensin System Studies
- Receptor Mechanisms and Signaling
- Animal Behavior and Welfare Studies
- Meat and Animal Product Quality
- Primate Behavior and Ecology
- Neurotransmitter Receptor Influence on Behavior
- Infant Health and Development
- Complementary and Alternative Medicine Studies
- Hormonal Regulation and Hypertension
- Neuroscience and Neuropharmacology Research
- Pain Management and Placebo Effect
- Tendon Structure and Treatment
- Biochemical Analysis and Sensing Techniques
- Skin and Cellular Biology Research
- Pediatric Pain Management Techniques
- Infectious Encephalopathies and Encephalitis
- Neuroinflammation and Neurodegeneration Mechanisms
Universidade Federal Rural do Rio de Janeiro
2013-2024
University of Cambridge
2010
Universidade Federal de São Paulo
2003-2005
Social relationships are crucial for the development and maintenance of normal behavior in non-human primates. Animals that raised isolation develop abnormal patterns persist even when they later reunited with their parents. In rodents, social is a stressful event associated decrease hippocampal neurogenesis but considerably less known about effects primates during transition from adolescence to adulthood. To investigate how affects young marmosets, these were isolated other members colony...
To (1) discover kinematic variables that differ between dogs with cranial cruciate ligament rupture (CCLR) and control (2) to identify suitable outcome for longitudinal studies on the effects of surgical interventions CCLR in dogs.In vivo case-control comparison.Dogs unilateral (n=16), no other detectable neurologic or orthopedic disease 10 without CCLR, neurologic, disease.Kinematic data was collected from as they walked at constant speed a treadmill, using an infrared camera system...
Spinal cord injuries (SCIs) initiate a series of molecular and cellular events in which inflammatory responses can lead to major neurological dysfunctions. The present study aims investigate whether bee venom (BV) acupuncture applied at acupoints ST36 (Zusanli) GV3 (Yaoyangquan) could minimize locomotor deficits the magnitude neural tissue losses, change balance between pro- anti-inflammatory cytokines after an SCI by compression. Wistar rats were subjected model compression 2-French Fogarty...
The role of sex and gender in accounting for individual pain behaviors is poorly understood. present study was conducted to determine whether neonatal nociceptive stimuli at postnatal day 1 (PD1) rats would lead a differential behavioral impact based on gender. Animals were divided 4 groups according treatment (two injections 4% formalin into the pad right paws PD1 or control) sensory threshold cognition tests performed adult using hot plate, open field, elevated plus maze forced swim tests....
In laboratory animals, acupuncture needs to be performed on either anesthetized or, if unanesthetized, restrained subjects. Both procedures up-regulate c-Fos expression in several areas of the central nervous system, representing therefore a major pitfall for assessment induced by electroacupuncture. Thus, order reduce effect acute restraint we used protocol repeated brain activated electroacupuncture adult male Wistar rats weighing 180-230 g. Repeated immobilization protocols (6 days, 1...
We investigated the effects of chronic administration sertraline (SERT; ∼20 mg kg −1 day in drinking water), a selective serotonin reuptake inhibitor, on water and sodium intake plasma levels oxytocin (OT) vasopressin (AVP) basal stimulated conditions. Basal was reduced SERT‐treated rats. After 24 h deprivation, rats treated with SERT for 21 days ingested less than control (9.7 ± 0.5 versus 20.0 0.9 ml, respectively, at 300 min after presentation, P < 0.0001). Subcutaneous injection 2 m...
Startle is a fast response elicited by sudden acoustic, tactile, or visual stimuli in variety of animals and humans. As the magnitude startle can be modulated external internal variables, it useful tool to study reaction stress. Our evaluated whether acupuncture change cardiac autonomic modulation (heart rate variability); behavioural (reactivity) endocrine (cortisol levels) parameters startle. Brazilian Sport horses (n = 6) were subjected model which an umbrella was abruptly opened near...
We determined if the dorsal raphe nucleus (DRN) exerts tonic control of basal and stimulated sodium water intake. Male Wistar rats weighing 300-350 g were microinjected with phosphate buffer (PB-DRN, N = 11) or 1 µg/0.2 µl, in a single dose, ibotenic acid (IBO-DRN, 9 to 10) through guide cannula into DRN observed for 21 days order measure appetite intake following situations: furosemide-induced depletion (20 mg/kg, sc, 24 h before experiment) low dose dietary captopril (1 mg/g chow). From...
Sound sensitive dogs have exaggerated responses to sound stimuli that can negatively impact the welfare of dog. Behavioural reactions combined with response involve a marked autonomic imbalance towards sympathetic predominance and release cortisol. The purpose present study was evaluate, in laboratory, cardiac modulation using heart rate variability (HRV) analysis, serum cortisol levels behavioural parameters sounds fireworks history sensitivity fireworks. Based on these data, combining...
We investigate the influence of brain serotonin depletion on sodium appetite. Rats depleted through systemic administration p-chlorophenylalanine (300 mg/kg, ip, for 2 days) showed an intense natriorexigenic response induced by (furosemide, 20 sc, 24 h before water and 1.8% NaCl presentation). Intake was always higher than that observed control group (12.9 ± 1.4 21.4 3.0 mL vs 5.7 1.2 12.7 1.6 mL, 30 300 min after saline After h, continued to be significantly compared (33.6±5.1 21.9±3.6 mL,P...
The role of serotonergic system in the feeding behaviorwas appraised by electrolytic lesions dorsal raphe nucleus (DRN) and administration para-chlorophenylalanine (PCPA, 3 mg/5 mul, icv). Chronic evaluations were accomplished through 120 360 days PCPA-injected DRN-lesioned rats, respectively. Acute food intake was evaluated fasted rats submitted to injection PCPA hydroxytryptophan (LHTP, 30 mg/kg, ip). exhibited 22-80% increase up sixth month, whereas obesity evident sustained whole period....
Acupuncture has been shown to have the beneficial effect of reducing stress responses in animals and humans. Pharmacopuncture is injection subclinical doses drugs into acupoints give therapeutic results without side effects. This study compared effects injecting usual dose acepromazine (ACP; 0.1 mg/kg, intramuscularly [I.M.]) with those pharmacopuncture (1/10 ACP at governing vessel 1 [GV 1] acupoint) on healthy horses undergoing road transport for 2.5 hours. Four different treatments were...
To induce status epilepticus (SE) followed by the subsequent onset of spontaneous recurrent seizures, thus characterizing a new model temporal lobe epilepsy in nonhuman primate.Male and female marmosets (Callithrix jacchus) (n = 18), ages between 2 8 years, were injected with domoic acid (0.5-4 mg/kg, i.p.) or saline, behaviorally assessed regard to presence acutely induced seizures for < 6 months seizures. Injection doses ranging from 3.5 4 mg/kg either did not SE resulted fatal SE. Even...
The objective of the present study was to compare effect electroacupuncture (EA) and carprofen (CP) on postoperative incisional pain using plantar incision (PI) model in rats. A 1-cm longitudinal made through skin, fascia muscles a hind paw male Wistar rats development mechanical thermal hypersensitivity determined over 4 days von Frey Hargreaves methods, respectively. Based experimental treatments received third day, animals were divided into following groups: PI+CP (CP, 2 mg/kg, po);...
We investigated the role of 5-HT2C receptors and serotonergic transmission in feeding behavior control quails. Administration serotonin releaser, fenfluramine (FEN) agonists, mCPP MK212, 1.0 3.3 mg/Kg induced significant inhibition food intake previously fasted fowls (0.71 +/- 0.18 g 0.47 0.2 g; 0.49 0.22 0.48 0.29 0.82 0.13 0.71 0.16 g, respectively). Control groups ranged from 2.89 0.21 to 2.97 60 min after reintroduction food, P < 0.0001). Similar results were obtained with normally fed...
The general appearance of the innervation samples skin from 10 young beagles was studied by using pan‐neuronal immunolabel PGP9.5, and quantitative data on density nerve fibres obtained. provide a baseline for development diagnostic test small fibre neuropathy in domestic dogs.