A5060917360- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Screening and Detection
- Statistical Methods and Inference
- Gastric Cancer Management and Outcomes
- Anorectal Disease Treatments and Outcomes
- Diverticular Disease and Complications
- Gene expression and cancer classification
- Ophthalmology and Visual Impairment Studies
- Colorectal and Anal Carcinomas
- Complex Network Analysis Techniques
- Bioinformatics and Genomic Networks
- Advanced Graph Neural Networks
- Advanced Statistical Methods and Models
- Esophageal Cancer Research and Treatment
- Functional Brain Connectivity Studies
- Gastrointestinal Tumor Research and Treatment
- CO2 Reduction Techniques and Catalysts
- Tensor decomposition and applications
- Genetic Associations and Epidemiology
- Catalysts for Methane Reforming
- Corneal surgery and disorders
- Full-Duplex Wireless Communications
- Bacterial biofilms and quorum sensing
- Antimicrobial agents and applications
- Machine Learning in Healthcare
Nanchong Central Hospital
2018-2025
North Sichuan Medical University
2009-2025
Shanghai Jiao Tong University
2024
Anhui University
2023-2024
Bengbu Medical College
2022-2023
University of Chinese Academy of Sciences
2019-2022
Beijing Institute of Big Data Research
2020-2022
Chinese Academy of Sciences
2020-2022
Hangzhou Medical College
2022
Affiliated Hospital of North Sichuan Medical College
2022
Objective: To determine the morbidity, mortality, and pathologic outcomes of transanal total mesorectal resection (taTME) versus laparoscopic excision (laTME) among patients with rectal cancer clinical stage I to III below peritoneal reflection. Background: Studies sufficient numbers allowing acceptance taTME for are lacking. Thus, we launched a randomized trial compare safety efficacy laTME. Methods: A randomized, open-label, phase 3, noninferiority was performed at 16 different hospitals...
Myopia in school-aged children is a public health issue worldwide; consequently, effective interventions to prevent onset and progression are required.To investigate whether SMS text messages parents increase light exposure time outdoors provide myopia control.This randomized clinical trial was conducted China from May 2017 2018, with participants observed for 3 years. Of 528 965 primary Anyang, 3113 were randomly selected. these, 268 grade 2 schoolchildren selected assigned control groups....
Importance Previous studies have demonstrated the advantages of short-term histopathological outcomes and complications associated with transanal total mesorectal excision (TME) compared laparoscopic TME. However, long-term oncological TME remain ambiguous. This study aims to compare 3-year disease-free survival Objective To evaluate between in patients rectal cancer. Design, Setting, Participants randomized, open-label, noninferiority, phase 3 clinical trial was performed 16 different...
To investigate the risk factors for myopia progression in primary school children and build prediction models by applying machine learning to longitudinal, cycloplegic autorefraction data. A total of 2740 from grade 1 6 were examined annually over a period 5 years. Myopia was determined as change autorefraction. Questionnaires administered gauge environmental factors. Each year, evaluated built training group then tested an independent hold-out using random forest algorithm. Six variables...
Abstract Photoreduction of CO 2 into valuable fuels using semiconductors has been known as a potential mean to simultaneously alleviate environmental and energy issues. Z‐scheme photocatalytic systems can realize spatial separation photogenerated charges ensure strong redox capability simultaneously. Particularly, the all‐solid‐state photocatalysts for non aqueous mediators have widely used reduction. This review provides comprehensive outlook essential components recent advancements in...
microRNA (miR)-92b is an oncogenic miRNA. F-box and WD-40 domain protein 7 (FBXW7/hCdc4) a tumor suppressor target of miR-92b-3p. This study was designed to investigate the effect miR-92b-3p on colorectal carcinoma (CRC) invasion. The expression levels in human HT29, HCT116, fetal colon (FHC) normal cells were detected. HT29 HCT116 transfected with either inhibitor or FBXW7 plasmids (pcDNA-FBXW7) combination siRNA-FBXW7. Cell viability, migration, invasion, colony formation, cell cycle,...
Abstract Heterogeneity is a hallmark of cancer, diabetes, cardiovascular diseases, and many other complex diseases. This study has been partly motivated by the unsupervised heterogeneity analysis for diseases based on molecular imaging data, which, network‐based analysis, accommodating interconnections among variables, can be more informative than that limited to mean, variance, simple distributional properties. In literature, there very research common limitation shared existing techniques...
The widespread utilization of mupirocin to treat methicillin-resistant Staphylococcus aureus (MRSA)-caused infectious diseases has led the emergence mupirocin-resistant (MuRSA), posing a serious global medical threat. In order counteract MuRSA, we develop d-α-tocopherol polyethylene glycol 1000 succinate (TPGS) modified and silver complex (TPGS/Mup-Ag) combat MuRSA. surfactivity TPGS endows Mup-Ag with homogeneous small particle size (∼16 nm), which significantly enhances bacterial...
Transanal total mesorectal excision is a promising surgical procedure for mid to low rectal cancer.This study aimed determine the short-term outcomes of Chinese patients treated with transanal excision.This was an observational using data from online registry system.Study participants were recruited 40 different centers across 15 provinces in China.Patients either benign or malignant disease who underwent and registered Total Mesorectal Excision Registry Collaborative May 2010 November 2019...
Total mesorectum excision (TME) is considered the standard surgical procedure for rectal-cancer treatment. Transanal TME (taTME) a new to treat low rectal cancer. Some published studies have proven that taTME can provide better-quality resected specimen in low-rectal-cancer patients comparison transabdominal procedure, yet long-term outcomes must be investigated. We designed this non-inferiority trial (TaLaR trial) compare short-term and between laparoscopic (lapTME) cancer.The TaLaR phase...
The network analysis plays an important role in numerous application domains including biomedicine. Estimation of the number communities is a fundamental and critical issue analysis. Most existing studies assume that known priori, or lack rigorous theoretical guarantee on estimation consistency. In this paper, we propose regularized embedding model to simultaneously estimate community structure unified formulation. proposed equips with novel composite regularization term, which pushes vector...
A Fe 3 C@C catalyst with defect-rich graphite shell exhibits C 5+ selectivity of 70.1% and CH 4 9.0%.
Background: Anastomotic leakage following a radical gastrectomy is serious complication of gastric cancer and esophagogastric junction cancer. The benefit intraoperative leak testing for the prevention postoperative anastomotic has been controversial. We introduce new procedure, which combines techniques gastroscopy, air, methylene blue (GAM) testing. Our objective was to evaluate efficacy safety GAM procedure compare surgical complications patients who underwent with without using...
Background: With the optimization of neoadjuvant treatment regimens, indications for intersphincteric resection (ISR) have expanded. However, limitations such as unclear surgical field, impaired anal function, and failure preservation still exist. Transanal total mesorectal excision can complement drawbacks ISR. Therefore, this study combined these two techniques proposed transanal endoscopic (taE-ISR), aiming to explore value novel technique in ultra-low rectal cancer. Material methods:...
Patients with chronic inflammatory disorders are at a higher risk of developing aggressive Merkel cell carcinoma (MCC). Diabetes is common inflammatory disease that possibly associated MCC; however, there still no reports on the association between hepatitis B virus (HBV) infection and MCC. Whether an these three diseases specific mechanisms behind their effects worth further research in future.We herein report rare case MCC extracutaneous nodal invasion Asian individual type 2 diabetes...
The aim of the study was to clarify role gastrokine 1 in process formation and development gastric cancer. expression cancer corresponding non-cancerous tissues 52 patients assessed with real-time fluorescence quantitative polymerase chain reaction (RT-PCR) immunohistochemistry. We also analyzed relationship between level clinicopathological characteristics. Gastrokine gene protein both cases significantly lower than (both P<0.01), but no significant found parameters including tumor...
We evaluated the causal effects of blood lipid levels on systemic lupus erythematosus with a two-sample Mendelian randomization analysis. Independent single-nucleotide polymorphisms related to lipids (p < 5 × 10−8) were selected as instrumental variables (IVs) from published genome-wide association study (GWAS). SLE GWAS analysis that included 4036 cases and 6959 controls European ancestry provided roles between result (SLE). The (MR) analyses. According inverse-variance weighted approaches,...
Abstract Summary Heterogeneity is a hallmark of many complex human diseases, and unsupervised heterogeneity analysis has been extensively conducted using high-throughput molecular measurements histopathological imaging features. ‘Classic’ based on simple statistics such as mean, variance correlation. Network-based takes interconnections well individual variable properties into consideration can be more informative. Several Gaussian graphical model (GGM)-based techniques have developed, but...
In cancer research, supervised heterogeneity analysis has important implications. Such been traditionally based on clinical/demographic/molecular variables. Recently, histopathological imaging features, which are generated as a byproduct of biopsy, have shown effective for modeling outcomes, and handful conducted such features. There two types extracted specific biological knowledge using automated processing software, respectively. Using both our goal is to conduct the first that satisfies...
Transanal total mesorectal excision (TaTME) is an alternative for mid-low rectal cancer. In China, this procedure has been performed in high-volume centers with structured training curriculums. The efficacy of the TaTME curriculums China still unclear. This multicenter study aimed to explore effectiveness China.Seven participated study. first 25 patients who underwent each center were enrolled. cohort, divided into 3 groups. 5 procedures (group 1) under proctoring according requirement...