A5031976075- Prostate Cancer Treatment and Research
- Advanced Radiotherapy Techniques
- Prostate Cancer Diagnosis and Treatment
- Polymer Surface Interaction Studies
- Renal cell carcinoma treatment
- Cancer, Lipids, and Metabolism
- Lung Cancer Treatments and Mutations
- Electrospun Nanofibers in Biomedical Applications
- Lung Cancer Diagnosis and Treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Elevator Systems and Control
- Bladder and Urothelial Cancer Treatments
- Cancer Genomics and Diagnostics
- Urinary and Genital Oncology Studies
- Job Satisfaction and Organizational Behavior
- Head and Neck Cancer Studies
- Metal-Organic Frameworks: Synthesis and Applications
- Surface Modification and Superhydrophobicity
- Impact of Technology on Adolescents
- RNA Interference and Gene Delivery
- Multiple and Secondary Primary Cancers
- Radiomics and Machine Learning in Medical Imaging
- SARS-CoV-2 and COVID-19 Research
- Ferroptosis and cancer prognosis
- Immunotherapy and Immune Responses
Peking University First Hospital
2018-2025
Peking University
2016-2025
Zhejiang Chinese Medical University
2025
Guangzhou University of Chinese Medicine
2022-2025
China Jiliang University
2020-2024
Genomics Research Center, Academia Sinica
2023-2024
Shanghai Ocean University
2024
Nanchang University
2021-2024
Fujian University of Traditional Chinese Medicine
2023-2024
Shenzhen University
2024
Employee innovation is the cornerstone of organization, and motivation for employee innovative behavior largely depends on leadership style leader. With economic development society, traditional authoritative can no longer adapt to psychological characteristics employees, who use new-era work concepts, techniques, social rules (hereafter, new generation workers). Inclusive based concept "fully inclusive equitable" in Chinese culture, it independent needs employees. At present, research...
Abstract Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress remain unclear. Here, we show that tumor cell-intrinsic ATP6V0A1 drives exogenous cholesterol-induced immunosuppression in CRC. facilitates cholesterol absorption CRC RAB guanine nucleotide exchange factor 1 (RABGEF1)-dependent endosome maturation, leading accumulation within endoplasmic reticulum and elevated production of...
Career sustainability is a well-researched issue in academics and other sectors. Technology advancements COVID-19 have jeopardized career sustainability. Numerous studies explored the influence of individual characteristics on sustainability, but few focused leadership. In addition, cultural factors must be considered because leadership rooted culture. particular, inclusive reflects traditional Chinese Therefore, based self-determination social exchange theories, we analyzed effects as well...
Abstract Background The increased number of older adults living alone has created a substantial care need. However, the utilization rate services and facilities to meet these needs are surprisingly low. Many experience difficulties accessing services, although it remains unclear how obstacles impede access services. This study explored experienced by urban in seeking community care. Methods A phenomenological was carried out participatory observation in-depth interviews were employed...
Inflammatory bowel disease (IBD) is a chronic and recurrent inflammatory disorder in gastrointestinal tract. Shen Ling Bai Zhu San (SLBZS), which has long history of use Traditional Chinese Medicine (TCM), been widely used to treat diseases. The isolated fractions TCM have also proved possess an important potential for treating diseases, are due their effective components.In this study, we examined the possibility that SLBZS its active may prevent DSS-induced colitis, investigated mechanisms...
The high turnover rate of new generation employees is becoming an increasingly important issue for business and academia. Based on self-determination theory conservation resource theory, our study explores the impact inclusive talent development model intention mediating role work passion. questionnaire 290 employees’ data from China, after common method biases reliability validity tests, we used SPSS, Mplus bootstrapping empirical analysis. result showed that includes diversified team...
Since the outbreak of Severe Acute Respiratory Syndrome Virus-2 (SARS-CoV-2) in 2019, more than 15 million spike protein sequences have been identified, raising a new challenge for development broadly protective vaccine against various emerging variants. We found that virus, like most other human viruses, depends on host-made glycans to shield conserved epitopes from immune response and demonstrated deletion glycan shields exposed highly elicited responses. In this study, we identified 17 14...
Dendritic cell-targeted mRNA–PNP vaccines.
Outpatient satisfaction is important in evaluating the performance of tertiary public hospitals China. However, only a few studies have examined interaction between outpatient and its related factors. This study aimed to explore relationship patient factors provincial hospitals. Six hundred outpatients three Nanchang, China, were randomly selected. Structural equation modeling was used analyze associated with satisfaction. The conceptual model fitted data well (χ2/df = 4.367, CFI 0.951, TLI...
The extract of the stems Eurya chinensis R. Br. yielded three new terpenes (1–3) including two diterpenes and one triterpene, named euryachins C–E, as well known (4–6). structures these novel compounds were elucidated via spectroscopic analysis, especially IR, NMR spectroscopy HRESIMS data. Besides, all isolated evaluated for antibacterial activity against Escherichia coli, Bacillus cereus, Staphylococcus aureus Methicillin-resistant S. (MRSA). Additionally, inhibitive COVID-19 was studied...
Smilax glabra flavonoids (SGF), the active components of Roxb., have been demonstrated to exhibit antioxidant activity and metabolic benefits in obesity, leading us further explore their antitumor effects obesity-related colorectal cancer (CRC). This study investigated antiproliferative SGF on CRC by using a murine colon adenocarcinoma MC38 cell line. The underlying mechanisms were explored via RNA-Seq bioinformatics analysis combination with experimental validation. was proven possess...
This study assesses the safety and disease control outcomes in metastatic renal cell carcinoma (mRCC) patients undergoing concurrent tyrosine kinase inhibitors (TKI), immune checkpoint (ICIs), high-dose stereotactic ablative body radiotherapy (SABR) . Between February 2020 to May 2023, 54 mRCC receiving vascular endothelial growth factor (VEGF) targeted therapy ICIs with (RT) were included. Genetic testing was performed on 25 pathology samples using Acornmed 70™ panel. Endpoints included...
<title>Abstract</title> Purpose This study aimed to comprehensively delineate the clinical characteristics, surgical interventions, and evolving trends over past decade among patients undergoing surgery for renal cell carcinoma (RCC). Methods A retrospective analysis was conducted on records of 9,110 diagnosed with RCC who underwent treatment at Peking University First Hospital between January 2013 December 2022. Statistical analyses were performed using SPSS 21.0 software. Categorical...
Introducing wrinkling or rough features into substrates is of great practical significance to construct various functional surfaces. Due the sensitivity assembled units towards environmental stimuli, internals layer-by-layer films can be readily adjusted generate micro- and nanostructures. We previously described a self-roughening polyelectrolyte multilayer (PEM) facilitate introduction surface microstructures. In present work, growth process PEI/PAA was investigated mean size...
1,4,5,8,9,12-Hexaazatriphenylene (HAT) is one of the smallest polyheterocyclic aromatic building blocks for forming conjugated metal-organic frameworks (cMOFs). However, strong inter-molecular steric hindrance impedes growth HAT-based cMOFs. Here we employ on-surface synthesis to grow single-layer two-dimensional cMOFs M3 (HAT)2 (M=Ni, Fe, Co). Using scanning tunnelling microscopy and density-functional theory (DFT) analysis, resolve that comprise a hexagonal lattice HAT molecules Kagome...
Achievement of an endothelial cell (EC) monolayer (re-endothelialization) on the vascular implant surface with competent and functioning features is critical for long-term safety after implantation. Oriented EC beneficial to improve function such as enhanced athero-resistant property. However, information about antithrombotic property oriented limited. Here, we used microgrooved polydimethylsiloxane substrates guide orientation obtain monolayer. The effects anisotropic topography behaviors...