A5100689209- IL-33, ST2, and ILC Pathways
- Psoriasis: Treatment and Pathogenesis
- Immune Cell Function and Interaction
- Asthma and respiratory diseases
- Immune Response and Inflammation
- Whipple's Disease and Interleukins
- Dermatology and Skin Diseases
- Genetics, Aging, and Longevity in Model Organisms
- Eosinophilic Esophagitis
- Urticaria and Related Conditions
- Complement system in diseases
- Mast cells and histamine
- Endometriosis Research and Treatment
- Eosinophilic Disorders and Syndromes
- Plant Reproductive Biology
- Reproductive System and Pregnancy
- interferon and immune responses
- Photosynthetic Processes and Mechanisms
- Endometrial and Cervical Cancer Treatments
- Pediatric health and respiratory diseases
Hong Kong University of Science and Technology
2024-2025
University of Hong Kong
2024-2025
Guangzhou Medical University
2014-2020
Ningbo University
2015-2020
Zhejiang Chinese Medical University
2016
Guangzhou Women and Children Medical Center
2014
Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
2011
Guangzhou Blood Center
2006
Summary We previously showed that γδT cells are involved in the pathogenesis of sepsis, but, underlying mechanisms remained unclear. The present study demonstrates, for first time, express complement C5a receptor (C5aR, CD88) and CD88 expression was up‐regulated mice following sepsis both at protein mRNA levels. Complement itself contributed to regulation C5aR on cells, as (i) neutralization vivo prevented septic (ii) incubation mouse spleen or purified with recombinant vitro increased by...
To observe preventive and therapeutic effects the mechanism of actions on Zishen Yutai pill combined with progesterone threatened abortion in rats.After pregnancy, 50 SPF female SD rats were selected divided into control group, model plus group (combination group), 10 each group. The lavaged 2 mL/kg normal saline pregnancy day 1 for continuous days. Rats given 1.575 g/kg/d intragastric administration intramuscular injection treatment 0.1 mL/d progestin, combination therapy aqueous solution...
BackgroundInterleukin (IL)-35 and IL-35–producing regulatory T cells (iTr35) have been reported to inhibit TH2 response in allergic rhinitis (AR). However, its effects on type II innate lymphoid (ILC2) are not well characterized.ObjectiveTo investigate the effect of IL-35 ILC2 AR.MethodsA total 25 patients with AR 20 controls were recruited. The expression regulation receptor analyzed by real-time polymerase chain reaction. differentiation cytokine production was reaction enzyme-linked...
Rheumatoid arthritis (RA) is considered a systemic chronic inflammatory joint disease characterized by synovitis and cartilage bone destruction. Interleukin-33 (IL-33) proinflammatory cytokine which highly expressed in the synovium of RA patients joints mice with collagen-induced (CIA) exacerbates CIA mice. However, role IL-33-neutralizing antibody murine model remains unclear. In present study, were given intraperitoneally polyclonal rabbit anti-murine IL-33 (anti-IL-33) or normal IgG...
Interleukin-27 (IL-27) has been reported to inhibit type 2 T helper cell (Th2) response in allergic rhinitis (AR). However, its effects on group II innate lymphoid cells (ILC2) AR are not fully understood. Nineteen patients with and nineteen controls were enrolled this study. The of IL-27 ILC2 differentiation function as well the regulation receptor (IL-27R) analyzed by tritiated thymidine incorporation, enzyme-linked immunosorbent assay (ELISA), real-time polymerase chain reaction (PCR),...
Summary Vitellogenin belongs to the Large Lipid Transfer Protein superfamily and is thought share a common ancestor with human Apolipoprotein B (ApoB) for systemic lipid transport 1–5 . forms part of yolk granules (also known as organelles), maternal contribution nutrients that support embryonic development oviparous animals 6,7 In Caenorhabditis elegans , vitellogenin proteins (VIT-1 VIT-6) are synthesized in hermaphrodite intestine, secreted into pseudocoelom internalized by oocytes 8–13...