A5033468696- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Cardiovascular Issues in Pregnancy
- Cardiac Valve Diseases and Treatments
- Coronary Artery Anomalies
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Pulmonary Hypertension Research and Treatments
- Cardiac Imaging and Diagnostics
- Vascular anomalies and interventions
- Aortic Disease and Treatment Approaches
- Tracheal and airway disorders
- Cardiomyopathy and Myosin Studies
- Cardiac pacing and defibrillation studies
- Liver Disease and Transplantation
- Heart Failure Treatment and Management
- Venous Thromboembolism Diagnosis and Management
- Pregnancy and preeclampsia studies
- Transplantation: Methods and Outcomes
- Maternal and fetal healthcare
- Cardiovascular Effects of Exercise
- Infective Endocarditis Diagnosis and Management
- Mechanical Circulatory Support Devices
- Congenital Diaphragmatic Hernia Studies
- Phonocardiography and Auscultation Techniques
Brigham and Women's Hospital
2016-2025
Harvard University
2016-2025
Boston Children's Hospital
2016-2025
Boston Children's Museum
2014-2024
Joint Commission
2023
Boston University
2012-2022
Columbia University Irving Medical Center
2011-2020
American Association for Thoracic Surgery
2018
Society for Cardiovascular Angiography and Interventions
2018
Society of Thoracic Surgeons
2014-2018
The "2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation" provides recommendations to guide clinicians in treatment patients with atrial fibrillation.
Background— The arrhythmia burden in tetralogy of Fallot, types arrhythmias encountered, and risk profile may change as the population ages. Methods Results— Alliance for Adult Research Congenital Cardiology (AARCC) conducted a multicenter cross-sectional study to quantify characterize age-related trends, identify associated factors. A total 556 patients, 54.0% female, 36.8±12.0 years age were recruited from 11 centers. Overall, 43.3% had sustained or intervention. Prevalence atrial...
<h3>Objective</h3> Patients with repaired tetralogy of Fallot (TOF) experience increased rates mortality and morbidity in adulthood. This study was designed to identify risk factors for death ventricular tachycardia (VT) a large contemporary cohort patients TOF. <h3>Methods</h3> Subjects TOF from four congenital heart centres the USA, Canada Europe were enrolled. Clinical, ECG, exercise, cardiac magnetic resonance (CMR) outcome data analysed. <h3>Results</h3> Of 873 (median age 24.4 years),...
Risk factors for adverse clinical outcomes have been identified in patients with repaired tetralogy of Fallot before pulmonary valve replacement (PVR). However, pre-PVR predictors post-PVR sustained ventricular tachycardia and death not identified.Patients enrolled the INDICATOR cohort (International Multicenter TOF Registry), a 4-center international study, who had comprehensive preoperative evaluation subsequently underwent PVR were included. Preprocedural clinical, ECG, cardiovascular...
The impact of pulmonary valve replacement (PVR) on major adverse clinical outcomes in patients with repaired tetralogy Fallot (rTOF) is unknown. purpose this study was to determine whether PVR associated improved survival and freedom from sustained ventricular tachycardia (VT) rTOF. A propensity score created adjust for baseline differences between non-PVR enrolled INDICATOR (International Multicenter TOF Registry). primary outcome time the earliest occurrence death or VT. were matched 1:1...
The underlying mechanisms that contribute to global right ventricular (RV) dysfunction in patients with repaired tetralogy of Fallot are incompletely understood. We therefore sought quantify regional RV abnormalities and determine the relationship these function exercise capacity.Clinical cardiac magnetic resonance data from 62 consecutive were analyzed (median age at follow-up 23 years [limits 9 67 years]). Using data, 3D endocardial surface models reconstructed segmented contours, a...
<h3>Objective</h3> The Fontan operation is a staged palliation for complex congenital heart disease and single ventricle physiology. Perioperative survivors of the experience long-term cardiac complications, including death. Liver renal dysfunction are reported in these patients have direct effect on morbidity mortality. This study aims to investigate whether Model End-stage Disease eXcluding INR score (function creatinine total bilirubin, MELD-XI) predicts risk mortality or transplantation...
<h3>Background</h3> Late complications of the Fontan operation represent a significant management challenge. Failing patients have two modes presentation: impaired ventricular function (IVF) and those with preserved (PVF) but failing physiology (protein-losing enteropathy [PLE] plastic bronchitis [PB]). This study evaluated whether referred for heart transplantation had different outcome based on mode presentation. <h3>Methods</h3> The medical records all at single institution from 1994 to...
Background— Significant morbidities, including angina, symptomatic heart failure, and myocardial infarction, have been reported after coronary artery fistula (CAF) closure; however, predictors that may be associated with adverse outcomes not established. The goal of this investigation is to describe the long-term witnessed in patients either treated or untreated CAF at our institution investigate whether certain features predicted outcomes. Methods Results— records angiograms who underwent a...
Objective To determine the association of pulmonary valve replacement (PVR) with death and sustained ventricular tachycardia (VT) in patients repaired tetralogy Fallot (rTOF). Methods Subjects rTOF cardiac magnetic resonance from an international registry were included. A PVR propensity score was created to adjust for baseline differences. consensus criteria predefined as regurgitation >25% ≥2 following criteria: right (RV) end-diastolic volume >160 mL/m 2 , RV end-systolic >80...