A5066468157- Eating Disorders and Behaviors
- Obesity, Physical Activity, Diet
- Obesity and Health Practices
- Diet and metabolism studies
- Behavioral Health and Interventions
- COVID-19 and Mental Health
- Digital Mental Health Interventions
- Mobile Health and mHealth Applications
- Health disparities and outcomes
- Nutritional Studies and Diet
- Cannabis and Cannabinoid Research
- Child and Adolescent Psychosocial and Emotional Development
- Mindfulness and Compassion Interventions
- Health Systems, Economic Evaluations, Quality of Life
- Physical Activity and Health
- Biochemical Analysis and Sensing Techniques
- Obsessive-Compulsive Spectrum Disorders
- Regulation of Appetite and Obesity
- Culinary Culture and Tourism
- Impact of Technology on Adolescents
- Cardiac Imaging and Diagnostics
- Consumer Attitudes and Food Labeling
- Health Policy Implementation Science
- Neuroscience and Neuropharmacology Research
- Speech and Audio Processing
University of Leeds
2016-2025
BP (United Kingdom)
2015-2024
The University of Sydney
2018-2024
MedStar Washington Hospital Center
2023-2024
Colorado School of Public Health
2024
University of Derby
2014-2023
University of Essex
2023
University of Cambridge
1992-2023
MRC Epidemiology Unit
2022-2023
University of Auckland
2023
Plant-derived cannabinoids (phytocannabinoids) are compounds with emerging therapeutic potential. Early studies suggested that cannabidiol (CBD) has anticonvulsant properties in animal models and reduced seizure frequency limited human trials. Here, we examine the antiepileptiform antiseizure potential of CBD using vitro electrophysiology an vivo model, respectively. (0.01–100 μM) effects were assessed Mg<sup>2+</sup>-free 4-aminopyridine (4-AP) epileptiform activity hippocampal brain slices...
Within the first year of distribution vaccines against COVID-19, high-income countries (HICs) have achieved vaccination rates 75-80%, whilst low-income (LICs) vaccinated &lt;10%. This disparity in access has been one greatest failures international cooperation during SARS-CoV-2 pandemic. Global COVID-19 vaccine inequity affects us all, with ongoing risk new variants emerging until global herd immunity is strengthened. The current model based on financial competition for limited supplies,...
BackgroundOlder adults were more likely to be socially isolated during the COVID-19 pandemic, with increased risk of depression and loneliness. We aimed investigate whether a behavioural activation intervention delivered via telephone could mitigate loneliness in at-risk older people pandemic.MethodsBASIL+ (Behavioural Activation Social Isolation) was pragmatic randomised controlled trial conducted among patients recruited from general practices England Wales, designed assess effectiveness...
<h3>Abstract</h3> <b>Objective:</b> To assess if a school based intervention was effective in reducing risk factors for obesity. <b>Design:</b> Group randomised controlled trial. <b>Setting:</b> 10 primary schools Leeds. <b>Participants:</b> 634 children aged 7-11 years. <b>Intervention:</b> Teacher training, modification of meals, and the development action plans targeting curriculum, physical education, tuck shops, playground activities. <b>Main outcome measures:</b> Body mass index, diet,...
OBJECTIVE. There is variation in the psychological distress associated with child obesity. Low self-esteem, when observed, provides very little information about nature of and no indication proportion obese children affected. This study used a domain approach to self-competence evaluate self-esteem representative sample Australian children. PARTICIPANTS AND METHODS. A total 2813 (mean age: 11.3 years) took part study. They were recruited from 55 schools all last 2 years primary school....
<h3>Abstract</h3> <b>Objectives:</b> To implement a school based health promotion programme aimed at reducing risk factors for obesity and to evaluate the implementation process its effect on school. <b>Design:</b> Data from 10 schools participating in group randomised controlled crossover trial were pooled analysed. <b>Setting:</b> primary Leeds. <b>Participants:</b> 634 children (350 boys 284 girls) aged 7-11 years. <b>Main outcome measures:</b> Response rates questionnaires, teachers9...
Dieting is a common practice among adolescent girls. Recent research suggests that dieting may not be benign and it becoming more frequent in younger age groups. The present study investigated motivation the underlying attitudes to body weight shape two Eighty‐four nine‐year‐old 86 14‐year‐old girls from same school completed assessments of dietary restraint, esteem, satisfaction figure preferences. girls' height were also measured. distribution restraint scores revealed individuals both...
Epilepsy is the most prevalent neurological disease and characterized by recurrent seizures. Here, we investigate (i) anticonvulsant profiles of cannabis-derived botanical drug substances (BDSs) rich in cannabidivarin (CBDV) containing cannabidiol (CBD) acute vivo seizure models (ii) binding CBDV BDSs their components at cannabinoid CB1 receptors.The two (50-422 mg·kg(-1) ) were evaluated three animal seizure. Purified CBD also an isobolographic study to evaluate potential pharmacological...