Globally, the leading cause of death from cancer in women is infection with human papillomavirus (HPV). This calls for imperative actions to explore anticancer drugs against this threatening viral infection, which case, natural ingredients are presumed be a promising source. Several studies show that plant-origin compounds such as allicin, apigenin, capsaicin, cyanidin, fisetin, genistein, laricitrin, naringenin, piperine, and syringetin have demonstrated therapeutic effects several types....

Heat stress is a major challenge in poultry production, particularly tropical and subtropical regions, as it negatively affects reproductive function male chickens. This study investigates the protective effects of Cucurbita moschata (pumpkin seed) extract on testicular histopathology heat-stressed A laboratory experimental design using Completely Randomized Design (CRD) was employed, involving 27 one-year-old roosters subjected to chronic heat (37–38°C, 75–80% humidity, 8 hours/day for 21...

Pumpkin seeds have been associated with myriad of medicinal uses in different part the world. The pumpkin seed is a rich natural source antioxidant. Till date researchers reported significant potential herbal drugs employed various traditional, complementary and alternative systems. pharmacological activity several plants has scientifically documented. present review useful for up-to investigations on Cucurbita moschata furthermore, we assessed possible protective efficacy extract sperm...

Background and Aim: Cervical cancer accounts for the fourth as a cause of death from in women worldwide, with more than 85% events deaths occurring developing countries. The main problems chemotherapy are lack selectivity drug resistance. This study aimed to investigate signal transduction chitosan-based Pinus merkusii bark extract nanoparticles (Nano-PMBE) an anticancer on HeLa cell line. Materials Methods: Nano-PMBE was prepared based ionic gelation method. Its activities cells were...

The aim of the study was to describe process neuron death in cerebral cortex caused by embryonic carbofuran exposure.81 mouse foetuses from 27 breeding mice were used study. Carbofuran administered gavage 6th 15th day gestation two groups: one at 0.0208 and other 0.0417 mg/kg b.w. On 17th day, sacrificed taken measure ROS (malondialdehyde/MDA superoxide dismutase/SOD) activity brain tissue, number apoptotic neurons using a TUNEL assay, necrotic cells HE staining. Examination p53 caspase 3...

Cervical cancer is a severe concern for women throughout the world. This percentage of incidence causes sufferers to die at high rate. It believed that bark

Pine bark was previously known as a waste product from the lumber industry, but it is now regarded natural ingredient that rich in proanthocyanidin content with potential medicinal properties. This study aimed to investigate cytotoxic effects of P. merkusii extract (PMBE) on WiDr, human colon carcinoma cell line. The cytotoxicity test PMBE performed using MTT assay. inhibited viability WiDr cells an IC50 235.60 μg/mL. Despite weak effect, current represents first report potency anticancer...

Cancer is a significant global health problem today and responsible for most deaths after cardiovascular diseases. One of the conventional modalities cancer treatment chemotherapy. However, it has many side effects complications. Therefore, search novel drug candidates from natural ingredients that are more effective have minimal critical. This study aimed to determine cytotoxic effect Allium cepa L. extract on human cervical cells. The cytotoxicity test procedure was performed using MTT...

Background: The needs of Indonesian people for animal protein from meat are still quite high, but the fulfillment demand has not been sufficient. Many obstacles faced by farmers in developing their livestock business, one which is helminthiasis. Helminth infections can occur due to feed problems or poor maintenance management. infestation digestive tract cause intestinal mucosal damage, reduce efficiency food absorption, causing productivity losses body weight, milk production, quality meat,...

Background: Cancer is one of the leading causes death in pets. Among various therapeutic methods, chemotherapy still main choice to treat advanced and metastatic cancers. However, because its non-target-specific mode action, often severe side effects patients. Purposes: This study aimed analyze cytotoxic effect red okra fruit extract (Abelmoschus esculentus) on HeLa cells with a comparison several incubation periods therapy. Methods: Red was extracted by maceration method using 96% ethanol....

Tujuan penelitian ini adalah membuktikan potensi dan efektivitas rat bone marrow mesenchymal stem cell (rbmmsc) sebagai terapi pada kasus teratogenik selama kebuntingan dengan melihat ekspresi tumor necrosis factor (TNF-α), Bax, Bcl-2. Dua puluh empat ekor tikus bunting model dibagi menjadi kelompok perlakuan yang berbeda yaitu P1-Kontrol (dipapar carbon black dosis 532 mg/m3 4 jam umur ke-6 s/d ke-11 + Injeksi MEM 0,1 ml), P1-Terapi rbmmsc 1x106 sel/0,1 P2-Kontrol ke-17 P2-Terapi...

Several efforts have been made to discover new anticancer agents based on natural ingredients. Meanwhile, previous studies shown that different Pine genus species exhibit cytotoxic activity against various types of cancer cells. This plant is rich in phenolic compounds, especially procyanidins, flavonoids, and acids. Therefore, this study aims investigate the vitro cytotoxicity Pinus merkusii needles extract HeLa cell lines. The assessment was measured using MTT assay expressed as IC 50...

Background: Indonesians have relatively high dietary requirements. Meat and processed items are frequently counterfeited in today's world. Pork is a low-cost protein provider that cheap readily available. As result, some traders began substituting the whole meat products with pork. In protecting community, BBVet Wates conducted ELISA Sandwich testing. Purpose: To find out addition of pork content effectiveness for species tests. Method: type sandwich. Result: 2019, there were 45 positive...

Background: The productivity of laying hens is a key measurement in the business. One targets for to achieve peak production. optimal production period necessary attain maximum profit. Purpose: To determine strain Lohman Brown aged 25-49 weeks at CV. Lawu Farm Malang Regency as an evaluation period. Case Analysis: descriptive method with case study technique was used. Primary data were obtained from observations by participating direct livestock activities, interviews, and documentation,...

Background: Subdistrict Parengan has high livestock potential especially Suciharjo Village and Margorejo Village. The existing agricultural waste is not treated properly cannot reach maximum weights. provision of quality animal feed one the efforts to improve welfare community. Quality can be increasing cattle productivity so that selling value will increase. Purpose: This Community Service activity aims economic strengthening community through breeders introduction, dissemination,...

Background: Making silage added with additives can improve the quality of nutrition and speed up fermentation process. Molasses are widely used by farmers as for making silage. The use molasses be replaced Fermented Mother Liquor (FML) in Purpose: to determine effect addition on physical chemical corn plant given (FML). Method: Observative data collection direct observations two treatments consist P0 (Corn Plant + 2% (FML)) P1 Molasses). storage time was one week seventh day were made each...

Introduction: Exotic pet lovers' interest in keeping tortoises is increasing all over the world, including Indonesia. However, this trend cannot be separated from potential emergence of various health problems tortoises. One that often affects metabolic bone disease. Metabolic disease (MBD) a disorder related to mechanisms vitamin D and calcium metabolism, which generally occurs reptiles, especially Chelonia Lizards. Case Presentation: A 3-month-old redfooted tortoise, was clinically...

Background: Differences in the use of concentrates dairy cows cause differences quantity and quality milk produced. Purpose: To compare between fed concentrate A B. Methods: This observation was carried out at KUD Kertajaya Kandangan Kediri using 40 with a ratio 20 The cow's samples tested lactoscan machine, then measured time milking scaled can. Results: results showed that had an average pH 6.495±0.176, specific gravity 1,0241±0.0004 g/ml, fat content 5,241±2.614%, protein 3,335±0.294%,...

Background: Air pollution in the form of Diesel Exhaust Particles emerging from motor vehicles are harmful to health that have adverse reproductive impacts, especially during pregnancy. The use stem cells treating white mice (Rattus norvegicus) exposed carbon black can reveal potential for treatment placental impairment Purpose: demonstrate effectivity Rat Bone Marrow Mesenchymal Stem Cell therapy on rats as observed caspase-3 expression. Methods: This research uses a completely randomized...

Tujuan pengabdian masyarakat ini adalah mengaplikasikan teknologi pembuatan pakan berupa dodol temulawak sebagai upaya untuk menggemukkan sapi potong di Desa Brangkal dan Cengkong Kecamatan Parengan Kabupaten Tuban. Rendahnya yang diberikan banyaknya hasil sampingan pertanian belum diolah secara maksimal merupakan masalah utama dari kedua mitra. Solusi permasalahan mitra dengan inovasi yaitu tambahan pengganti konsentrat mempunyai kandungan sumber energi protein baik. Bahan aditif digunakan...

Sperm motility patterns can be used to analyze the level of activity sperm cells. The test is carried out on a microscopic in medical laboratory. In general, cell ratings are subjectively conducted by expert analyst. Imaging pattern analyzer helpful detect position and movement cells using video recording from digital microscope device. By optical flow, direction object determined keep track becomes pattern. this paper, data mice Data were analyzed average distance frame rate for comparing...

Dermatomycosis is generally said to be a skin disease caused by fungus, without needing know the species of fungus. Animals are hosts for various pathogenic fungi that also infective humans. Onesources thetransmission humans mediated pets. Transmission from one host another can through direct contact or an intermediary. zoonotic disease. To determine procedure, clinical symptoms, examination, and treatment cats with dermatomycosis on outpatients at Healthypet Veterinary Clinic. This done...