A5025394086- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Health, Environment, Cognitive Aging
- Noise Effects and Management
- Birth, Development, and Health
- Asthma and respiratory diseases
- Nutritional Studies and Diet
- Urban Green Space and Health
- Allergic Rhinitis and Sensitization
- Air Quality Monitoring and Forecasting
- Global Health Care Issues
- Urban Transport and Accessibility
- Energy and Environment Impacts
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Health disparities and outcomes
- Thermoregulation and physiological responses
- Delphi Technique in Research
- Effects and risks of endocrine disrupting chemicals
- Vehicle emissions and performance
- Land Use and Ecosystem Services
- Urban Heat Island Mitigation
- Per- and polyfluoroalkyl substances research
- Urban Agriculture and Sustainability
- Circadian rhythm and melatonin
- Indoor Air Quality and Microbial Exposure
Barcelona Institute for Global Health
2016-2025
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2016-2025
Universitat Pompeu Fabra
2016-2025
Instituto de Salud Carlos III
2015-2025
Hospital Del Mar
2011-2023
Hospital del Mar Research Institute
2013-2023
Municipal Institute for Medical Research
2010-2023
Centre for Biomedical Network Research on Rare Diseases
2023
Agència de Salut Pública de Catalunya
2014-2022
Parc de Salut
2021-2022
Significance Green spaces have a range of health benefits, but little is known in relation to cognitive development children. This study, based on comprehensive characterization outdoor surrounding greenness (at home, school, and during commuting) repeated computerized tests schoolchildren, found an improvement associated with greenness, particularly at schools. association was partly mediated by reductions air pollution. Our findings provide policymakers evidence for feasible achievable...
Air pollution is a suspected developmental neurotoxicant. Many schools are located in close proximity to busy roads, and traffic air peaks when children at school. We aimed assess whether exposure of primary school traffic-related pollutants associated with impaired cognitive development.We conducted prospective study (n = 2,715, aged 7 10 y) from 39 Barcelona (Catalonia, Spain) exposed high low pollution, paired by socioeconomic index; were tested four times (i.e., the 12-mo trajectories)...
Abstract Over 70,000 excess deaths occurred in Europe during the summer of 2003. The resulting societal awareness led to design and implementation adaptation strategies protect at-risk populations. We aimed quantify heat-related mortality burden 2022, hottest season on record Europe. analyzed Eurostat database, which includes 45,184,044 counts death from 823 contiguous regions 35 European countries, representing whole population over 543 million people. estimated 61,672 (95% confidence...
Background: Green spaces have been associated with improved mental health in children; however, available epidemiological evidence on their impact child behavioral development is scarce.Objectives: We investigated the of contact green and blue (beaches) indicators symptoms attention deficit/hyperactivity disorder (ADHD) schoolchildren.Methods: This study was based a sample 2,111 schoolchildren (7–10 years age) from 36 schools Barcelona 2012. obtained data time spent beaches Strengths...
Background: Developmental periods in early life may be particularly vulnerable to impacts of environmental exposures. Human research on this topic has generally focused single exposure–health effect relationships. The "exposome" concept encompasses the totality exposures from conception onward, complementing genome.Objectives: Early-Life Exposome (HELIX) project is a new collaborative that aims implement novel exposure assessment and biomarker methods characterize early-life multiple factors...
Green spaces have been associated with both health benefits and risks in children; however, available evidence simultaneously investigating these conflicting influences, especially association different types of greenness, is scarce.We aimed to evaluate greenness children, terms sedentary behavior (represented by excessive screen time), obesity, current asthma, allergic rhinoconjunctivitis.We conducted a cross-sectional study population-based sample 3,178 schoolchildren (9-12 years old)...
<h3>Background</h3> Chronic obstructive pulmonary disease (COPD) is increasingly considered a heterogeneous condition. It was hypothesised that COPD, as currently defined, includes different clinically relevant subtypes. <h3>Methods</h3> To identify and validate COPD subtypes, 342 subjects hospitalised for the first time because of exacerbation were recruited. Three months after discharge, when stable, symptoms quality life, lung function, exercise capacity, nutritional status, biomarkers...
Mortality has been shown to increase with extremely hot ambient temperatures. Details on the specific cause of mortality can be useful for improving preventive policies. Infants are often identified as a population that is vulnerable extreme heat conditions; however, information and infant scarce, no studies reporting cause-specific mortality.The study includes all deaths in Catalonia region Spain during warm seasons 1983-2006 (503,389 deaths). We used case-crossover design evaluate...
There is a need to improve asthma characterisation by integrating multiple aspects of the disease. The aim present study was identify distinct phenotypes applying latent class analysis (LCA), model-based clustering method, two large epidemiological studies. Adults with who participated in follow-up Epidemiological Study on Genetics and Environment Asthma (EGEA2) (n = 641) European Community Respiratory Health Survey (ECRHSII) 1,895) were included. 19 variables covering personal...
Cross-sectional studies suggest an association between exposure to ambient air pollution and atherosclerosis. We investigated the outdoor quality progression of subclinical atherosclerosis (common carotid artery intima-media thickness, CIMT).We examined data from five double-blind randomized trials that assessed effects various treatments on change in CIMT. The were conducted Los Angeles area. Spatial models land-use used estimate home mean concentration particulate matter up 2.5 micrometer...
Background: Green spaces have been associated with improved physical and mental health; however, the available evidence on impact of green pregnancy is scarce.Objectives: We investigated association between surrounding greenness birth weight, head circumference, gestational age at delivery.Methods: This study was based 2,393 singleton live births from four Spanish cohorts (Asturias, Gipuzkoa, Sabadell, Valencia) located in two regions Iberian Peninsula distinct climates vegetation patterns...
By 2050, nearly 70% of the global population is projected to live in urban areas. Because environments we inhabit affect our health, and transport designs that promote healthy living are needed.We estimated number premature deaths preventable under compliance with international exposure recommendations for physical activity (PA), air pollution, noise, heat, access green spaces.We developed applied Urban TranspOrt Planning Health Impact Assessment (UTOPHIA) tool Barcelona, Spain. Exposure...
Essential to exposome research is the collection of data on many environmental exposures from different domains in same subjects. The aim Human Early Life Exposome (HELIX) study was measure and describe multiple during early life (pregnancy childhood) a prospective cohort associate these with molecular omics signatures child health outcomes. Here, we recruitment, measurements available baseline HELIX populations.The represents collaborative project across six established ongoing longitudinal...
Green spaces are reported to improve health status, including beneficial effects on pregnancy outcomes. Despite the suggestions of air pollution-related benefits green spaces, there is no available evidence impact greenness personal exposure pollution.We investigated association between surrounding and pollution among pregnant women explore potential mechanisms, if any, behind this association.In total, 65 rounds sampling were carried out for 54 who resided in Barcelona during 2008-2009....
We investigated whether traffic-related air pollution and noise are associated with incident hypertension in European cohorts. included seven cohorts of the study for effects (ESCAPE). modelled concentrations particulate matter aerodynamic diameter ≤2.5 µm (PM2.5), ≤10 (PM10), >2.5, (PMcoarse), soot (PM2.5 absorbance), nitrogen oxides at addresses participants land use regression. Residential exposure to traffic was facade according EU Directive 2002/49/EC. assessed as (i) self-reported (ii)...
BACKGROUND: Chemical and nonchemical environmental exposures are increasingly suspected to influence the development of obesity, especially during early life, but studies mostly consider single exposure groups.OBJECTIVES: Our study aimed systematically assess association between a wide array early-life childhood using an exposome-wide approach.METHODS: The HELIX (Human Early Life Exposome) measured child body mass index (BMI), waist circumference, skinfold thickness, fat in 1,301 children...
Background:The exposome constitutes a promising framework to improve understanding of the effects environmental exposures on health by explicitly considering multiple testing and avoiding selective reporting. However, studies are challenged simultaneous consideration many correlated exposures.Objectives:We compared performances linear regression–based statistical methods in assessing exposome-health associations.Methods:In simulation study, we generated 237 exposure covariates with realistic...