A5069260620- Gut microbiota and health
- Probiotics and Fermented Foods
- Microbial Metabolites in Food Biotechnology
- Diet and metabolism studies
- Gastrointestinal motility and disorders
- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- Clostridium difficile and Clostridium perfringens research
- Infant Nutrition and Health
- Helicobacter pylori-related gastroenterology studies
- Digestive system and related health
- Biochemical Analysis and Sensing Techniques
- Mycotoxins in Agriculture and Food
- Protein Hydrolysis and Bioactive Peptides
- Enzyme Production and Characterization
- Aluminum toxicity and tolerance in plants and animals
- Genomics and Phylogenetic Studies
- Liver Disease Diagnosis and Treatment
- Food composition and properties
- Fungal Biology and Applications
- Bacteriophages and microbial interactions
- Polysaccharides and Plant Cell Walls
- Phytochemicals and Antioxidant Activities
- Food Allergy and Anaphylaxis Research
- Oral microbiology and periodontitis research
Jiangnan University
2016-2025
State Key Laboratory of Food Science and Technology
2016-2025
Yangzhou University
2020-2024
First People's Hospital of Chongqing
2020-2024
University of Arizona
2024
Shihezi University
2020-2024
State Council of the People's Republic of China
2016-2017
Wuxi Institute of Technology
2016-2017
China Association of Acupuncture-Moxibustion
2017
Chinese Academy of Agricultural Sciences
2016
Host genotype and gender are among the factors that influence composition of gut microbiota. We studied population structure microbiota in two lines chickens maintained under same husbandry dietary regimes. The lines, which originated from a common founder population, had undergone 54 generations selection for high (HW) or low (LW) 56-day body weight now differ by more than 10-fold at age. Of 190 microbiome species, 68 were affected (line), interactions. Fifteen species belong to...
ABSTRACT The heavy metal cadmium (Cd) is an environmental pollutant that causes adverse health effects in humans and animals. Our previous work demonstrated oral administration of probiotics can significantly inhibit Cd absorption the intestines mice, but further evidence needed to gain insights into related protection mode. goal this study was evaluate whether through routes other than binding, with a focus on gut barrier protection. In vitro assay, both intervention therapy treatments...
ABSTRACT This study evaluated the protective effects of Lactobacillus plantarum CCFM8610, a selected probiotic with good cadmium binding capacity, against acute toxicity in mice. Ninety mice were divided into prevention and therapy groups. In groups, CCFM8610 was administered at 10 9 CFU once daily for 7 days, followed by single oral dose chloride 1.8 mg each mouse. same 2 days after an identical exposure. Mice that received neither nor culture or alone served as negative positive controls,...
Variations in selenium (Se) intake have been reported to affect the barrier function and immune responses gut. Previous studies mainly focused on role of Se itself or its metabolites, while influences Se-intake-related microbiota gut health were not thoroughly studied. This study compared effects different dietary supplementation (Se-deficient, Se-adequate, Se-supranutritional) mice. Fecal transplantation (FMT) was further conducted bypass effect provided direct evidence that intestinal are...
Our previous study confirmed the ability of Lactobacillus plantarum CCFM8610 to protect against acute cadmium (Cd) toxicity in mice. This was designed evaluate protective effects chronic Cd mice and gain insights into protection mode this strain. Experimental were divided two groups exposed for 8 weeks via drinking water or intraperitoneal injection. Both further four subgroups, control, only, plus CCFM8610. Levels measured feces, liver, kidneys, alterations several biomarkers noted. The...
Prebiotics play a widely recognized role in the regulation of intestinal microbiota, but most related studies have not been explored beyond genus level. In recent years, some newly publicized findings opened window opportunity regarding dietary tuning colonization by specific groups gut bacteria. For example, seaweed polysaccharides were shown to enrich Bacteroides spp., while galacto-oligosaccharides (GOS) could specifically certain strains Bifidobacterium adolescentis. This review was...
The roles of Bacteroides species in alleviating inflammation and intestinal injury has been widely demonstrated, but few studies have focused on the vulgatus. In this study, four B. vulgatus strains were selected, based their genomic characteristics, to assess ability alleviate lipopolysaccharide (LPS)-induced acute C57BL/6J mice. Alterations microbiota, epithelial permeability, cytokine level, short-chain fatty acid (SCFA) concentration, immune responses investigated following LPS-induced...
Edible mushrooms as valuable health foods have potential beneficial effects, and these activities are connected with the modulation of gut microbiota. In this review, we discuss regulation microbiota by edible mushroom. Ganoderma lucidum increases Bacteroides/Firmicutes ratio, promote growth anti-inflammatory short-chain fatty acid (SCFA) producing bacteria. Hericium erinaceus maintains intestinal barrier integrity, diversity richness Lentinula edodes act a prebiotic, SCFA-producing bacteria...
Akkermansia muciniphila is a commensal bacterium of the gut mucus layer. Although both in vitro and vivo data have shown that A. strains exhibit strain-specific modulation functions, its ability to moderate immunity ulcerative colitis not been verified. We selected three isolated human (FSDLZ39M14, FSDLZ36M5 FSDLZ20M4) type strain ATCC BAA-835 examine effects different on dextran sulfate sodium-induced colitis. All were cultured anaerobically brain heart infusion medium supplemented with...
There is mounting evidence that the microbiota-gut-brain axis (MGBA) critical in pathogenesis and progression of Parkinson's disease (PD), suggesting probiotic therapy restoring gut microecology may slow down progression. In this study, we examined disease-alleviating effects Bifidobacterium breve CCFM1067, orally administered for 5 weeks a PD mouse model. Our study shows supplementation with B. CCFM1067 protected dopaminergic neurons suppressed glial cell hyperactivation neuroinflammation...