A5100371687- Cancer Mechanisms and Therapy
- Mechanisms of cancer metastasis
- Cancer-related molecular mechanisms research
- Kruppel-like factors research
- Metastasis and carcinoma case studies
- Immunodeficiency and Autoimmune Disorders
- Cancer-related gene regulation
- Circular RNAs in diseases
- Reproductive System and Pregnancy
- Myasthenia Gravis and Thymoma
- Reproductive tract infections research
- MicroRNA in disease regulation
- Blood disorders and treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Cytokine Signaling Pathways and Interactions
- Immune Cell Function and Interaction
- Mast cells and histamine
- Microbial infections and disease research
- Syphilis Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Eosinophilic Esophagitis
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Liver Diseases and Immunity
- Flavonoids in Medical Research
Zhejiang Chinese Medical University
2020-2024
Weatherford College
2024
CM Hospital
2024
Shaanxi University of Chinese Medicine
2018-2023
Wenzhou Hospital of Traditional Chinese Medicine
2017-2022
Hangzhou Medical College
2021
Zhejiang Provincial People's Hospital
2021
Jiamusi University
2019
University of Benin
2018
First Affiliated Hospital of Jiamusi University
2018
High Immunoglobulin E(IgE) levels associated with hypersensitivity or parasitic infection were well established, but the clinical significance of ultra-low IgE was largely unknown. Previous studies indicated these patients have an elevated risk cancer, large-scale epidemiological on prevalence and manifestations are still lacking. A total 62,997 who admitted to First Affiliated Hospital Wenzhou Medical University had level tests from January 2010 March 2020 included. Patients serum < 2 IU/mL...
Various indices have been used to assess Crohn's disease (CD). However, the question of whether Disease Activity Index (CDAI) is associated with coagulation function has not fully confirmed. In this study, we examined association between CDAI and fibrinolysis parameters. a retrospective observational cohort 108 patients from two hospital centers was calculated, its correlations prothrombin time (PT), activated partial thromboplastin (APTT), thrombin (TT), international normalization ratio...
Mycoplasma hominis is the smallest prokaryotic microorganism with no cell wall, high pleomorphism, and slower reproduction than bacteria. It difficult for clinical technicians to find M. through negative Gram staining of specimens. Therefore, it likely miss detection in routine smear etiological examination. generally considered be a common colonizing bacterium urogenital tract low pathogenicity, usually invade submucosal tissue enter bloodstream.The abscesses patient were examined...
Background Malignant pleural effusion (MPE) is common and diagnosis often problematic. A cancer ratio (serum lactate dehydrogenases: adenosine deaminase ratio) has been proposed for diagnosing MPE. However, the usefulness of this “cancer ratio” clinical‐radiological criteria MPE not clearly determined to date. The aim study was assess performance those parameters in Methods We analyzed 240 patients including 120 with non‐MPE (93 tuberculous 27 parapneumonic). Patients were divided into two...
Abstract Background Selective immunoglobulin M deficiency (SIgMD) is a rare primary immunodeficiency that frequently reported in Western countries. However, large epidemiological and clinical studies of SIgMD China are still lacking. Herein, we describe cohort subjects tertiary university hospital China. Methods A cross‐sectional study included 139 668 participants at First Affiliated Hospital Wenzhou Medical University from January 2014 to October 2018 was conducted. Individuals with serum...
Abstract Objectives We evaluated the protective effects of protein phosphatase 2A (PP2A)/tristetraprolin (TTP) against brain edema in a rat model cerebral hemorrhage, bleeding that occurs tissues and ventricles. TTP is well‐known mRNA‐binding essential regulatory molecule for gene expression. Methods Cerebral hemorrhage was induced male albino rats divided into four homogeneous groups: normal control (I), (II), PP2A siRNA (III), scrambled (IV). Neurological scores, caspase‐3 mRNA expression,...
Recently, the rise of syphilitic seroresistance brings great confusion to clinical diagnosis and treatment syphilis, no clear diagnostic marker has been found distinguish from other progression syphilis. This study evaluated serum chemokines levels CCL2, CXCL8, CXCL9, CXCL10 its correlation with blood routine, coagulation, biochemical indexes in seroresistant patients.Serum were quantitatively determined by Flow Cytometric Bead Array (CBA). The results expressed pg/ml. Clinical parameters...
Abstract Background Selective immunoglobulin A deficiency (SIgAD) is the most common primary antibody disease and frequently reported in Western countries. However, large‐scale epidemiologic studies on SIgAD China are still lacking. Methods The clinical information of 555 180 subjects (age >4 years) including outpatient, inpatient, healthy who had ordered serum A, G, M 9 hospitals Zhejiang Province was collected. individuals were defined as IgA level <0.07 g/L with normal levels IgG...
Purpose: To investigate the protective effect of baicalein against chronic seizures in pentylenetetrazole induced epilepsy a rat model.Methods: A model was prepared by administration at dose 35 mg/kg to Sprague-Dawley rats. The animals were divided into 6 groups (5 rats/group): normal control, (untreated epilepsy) and four treatment that received separately, intraperitoneal injection 20, 30, 40 50 baicalein, respectively, on alternate days for 30 days. On each day following treatment,...
Abstract Background Good's syndrome (GS) is a rare secondary immunodeficiency disease presenting as thymoma and hypogammaglobulinemia. Due to its rarity, the diagnosis of GS often missed. Methods We used hospital information system retrospectively screen hypogammaglobulinemia patients at First Affiliated Hospital Wenzhou Medical University from Apr 2012 2020. The clinical, laboratory, treatment, outcome data for these were collected analyzed. Results Among 181 screened patients, 5 with...
Good's syndrome (GS) is a rare secondary immunodeficiency which characterized by hypogammaglobulinemia and thymoma. This study aims to investigate the expression distribution of B cells in thymoma tissue, given that had been found be reduced or absent peripheral blood bone marrow. retrospectively analyzed tissues from 5 GS patients at First Affiliated Hospital Wenzhou Medical University Zhejiang Provincial People's Hospital. Tissues 20 with simple were used as controls. Immunohistochemistry...
Background: Herpes zoster is a common viral skin infection and has high incidence rate in China. At present, conventional drugs combined with adjuvant measures are used for treatment. To improve the efficiency shorten time of treatment, we propose use pulsed microcurrent as new therapy. Aim: This study aimed to investigate effects on pain, depression, anxiety patients herpes zoster. Methods: A total 58 who were admitted our hospital between April August 2022 selected participants divided...
Objective: To improve the dosage form and evaluate quality of Gan Mai Dazao decoction. Methods: Oral liquid was extracted by traditional decocting method, Jujube Liquor ice in oral examined TLC. Results: clarified odorless, which accords with requirements Chinese pharmacopoeia 2015 edition for liquid. The TLC results were clear, well separated, highly specific negative without interference. Conclusion: In study prepared conforms to pharmacopoeia, provides a basis further developing
<p>Legends for Supplementary Figures S1-S10.</p>
<p>Supplementary Figure S3. Enforced expression of miR-29s in MGC803 and HGC27 cells.</p>
<p>Supplementary Figure S1. miR-29s expression analyses in GC cells.</p>
<p>Supplementary Figure S2. Correlations between miR-29s levels and histological grade of GCs.</p>
<p>Supplementary Figure S4. miR-29s inhibitors suppress the expression of endogenous in GC cells.</p>