A5092096090- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Single-cell and spatial transcriptomics
- Fetal and Pediatric Neurological Disorders
- MRI in cancer diagnosis
- Migraine and Headache Studies
- Radiomics and Machine Learning in Medical Imaging
- Cell Image Analysis Techniques
- Glioma Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Advanced Fluorescence Microscopy Techniques
- Ophthalmology and Eye Disorders
- Cerebrospinal fluid and hydrocephalus
Beijing Tian Tan Hospital
2023-2024
Capital Medical University
2023-2024
Quantifying neuron morphology and distribution at the whole-brain scale is essential to understand structure diversity of cell types. It exceedingly challenging reuse recent technologies single-cell labeling imaging study human brains. We propose adaptive tomography (ACTomography), a low-cost, high-throughput, high-efficacy approach, based on targeting individual cells. established platform inject dyes into cortical neurons in surgical tissues 18 patients with brain tumors or other...
Abstract Objective To explore whether MRI‐visible enlarged perivascular spaces (EPVS) are associated with migraine and may serve as a predictor of migraine. Then further its correlation chronification. Methods A total 231 participants (healthy control [HC] = 57, episodic [EM] 59, chronic [CM] 115) were included in this case–control study. 3T MRI device the validated visual rating scale used to assess grades EPVS centrum semiovale (CSO), midbrain (MB), basal ganglia (BG). Comparisons between...
Abstract Background New daily persistent headache (NDPH) is a rare primary disorder characterized by and sudden onset headaches. The pathogenesis of NDPH remains unclear, there are few white matter imaging studies related to NDPH. purpose this study was investigate the micro-structural abnormalities in provided insights into disease based on tract-based spatial statistics (TBSS). Methods Twenty-one patients with 25 healthy controls (HCs) were included study. T1 structural diffusion magnetic...
Abstract Background New daily persistent headache (NDPH) is a rare primary with unclear pathogenesis. Neuroimaging studies of NDPH are limited, and controversy still exists. Diffusion tensor imaging (DTI) commonly used to study the white matter. However, lacking specificity, potential pathological mechanisms matter microstructural changes remain poorly understood. In addition, intricacy gray structures impedes application DTI model. Here, we applied an advanced diffusion model neurite...
To delineate the structural connectome alterations in patients with chronic migraine (CM), episodic (EM), and healthy controls (HCs). The pathogenesis of chronification remains elusive, brain network changes potentially playing a key role. However, there is paucity research employing graph theory analysis to explore whole networks CM EM. individual 60 CM, 34 EM, 39 control participants were constructed by using deterministic diffusion-tensor tractography. Graph metrics including global...
New daily persistent headache (NDPH) is a rare primary disorder characterized by and sudden onset headaches. Specific abnormalities in gray matter white structure are associated with pain, but have not been well studied NDPH. The objective of this work to explore the fiber tracts structural connectivity, which can help reveal unique regional radiomics similarity networks were calculated from T1 weighted (T1w) MRI depict structure. connectivity matrices diffusion metrics like fractional...