- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Lipid metabolism and disorders
- Diet and metabolism studies
- Alcohol Consumption and Health Effects
- Hepatitis C virus research
- Gut microbiota and health
- Endoplasmic Reticulum Stress and Disease
- Liver Diseases and Immunity
- Diabetes Treatment and Management
- Diabetes and associated disorders
- Liver Disease and Transplantation
- Pancreatitis Pathology and Treatment
- Respiratory Support and Mechanisms
- Adipose Tissue and Metabolism
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipid metabolism and biosynthesis
- Dietary Effects on Health
- Metabolism, Diabetes, and Cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes Management and Research
- Pancreatic function and diabetes
- Cardiovascular Disease and Adiposity
- Hepatocellular Carcinoma Treatment and Prognosis
- Obstructive Sleep Apnea Research
Ospedale San Luigi Gonzaga
2023-2025
University of Turin
2012-2024
Ospedale Sacro Cuore Don Calabria
2024
Ospedale Humanitas Gradenigo
2013-2023
Humanitas University
2019
Azienda Ospedaliero Universitaria San Giovanni Battista
2008-2018
CTO Hospital
2010
National Research Council
2009
University of Padua
2003
Ospedale Microcitemico
2003
This study aims to determine the presence of components metabolic syndrome in primary nonalcoholic steatohepatitis (NASH) and assess role liver disease genesis peripheral hyperinsulinemia. Nineteen patients (18 men 1 woman; mean age, +/- SD, 38 10 years; body mass index [BMI], 26 2 kg/m(2)) with histologic evidence NASH were enrolled; 19 age- sex-matched normal subjects investigated as controls. Plasma glucose, insulin, C-peptide levels measured during an oral glucose tolerance test, a...
The relations of dietary habits to insulin sensitivity and postprandial triglyceride metabolism were evaluated in 25 patients with nonalcoholic steatohepatitis (NASH) age–, body mass index (BMI)–, gender–matched healthy controls. After a 7–day alimentary record, they underwent standard oral glucose tolerance test (OGTT), the (ISI) was calculated from OGTT; an fat load also performed 15 intake NASH richer saturated (13.7% ± 3.1% vs. 10.0% 2.1% total kcal, respectively, P = .0001) cholesterol...
Nonalcoholic fatty liver disease (NAFLD) encompasses a histological spectrum ranging from simple steatosis to nonalcoholic steatohepatitis (NASH). NAFLD carries higher risk of cardio-metabolic and liver-related complications, the latter being confined NASH demanding specific treatment. We assessed efficacy proposed treatments for NAFLD/NASH by reviewing reports randomized controlled trials (RCTs) on online databases national international meeting abstracts through January 2010. Primary...
Abstract Circulating levels of four adipokines (adiponectin, TNF-α, leptin, and resistin) the postprandial lipid adiponectin responses to an oral fat load were assessed in 25 non-obese, non-diabetic patients with biopsy-proven nonalcoholic steatohepatitis (NASH) correlated metabolic indices liver histology. was lower NASH compared controls (5,476 ± 344 vs. 11,548 836 ng/mL; P = .00001) on multiple regression analysis negatively steatosis, necroinflammation (OR 5.0; .009), fibrosis 8.0;...
The ability of the Adult Treatment Panel III (ATP III) criteria metabolic syndrome to identify insulin-resistant subjects at increased cardiovascular risk is suboptimal, especially in absence obesity and diabetes. Nonalcoholic fatty liver disease (NAFLD) associated with insulin resistance emerging as an independent factor. We compared strength associations ATP NAFLD resistance, oxidative stress, endothelial dysfunction nonobese nondiabetic subjects.Homeostasis model assessment (HOMA-IR) >2,...
The relationships between the adipokines tumor necrosis factor (TNF)-alpha and adiponectin parameters of glucose homeostasis severity liver disease were assessed in nonobese nondiabetic subjects with nonalcoholic steatohepatitis (NASH).A frequently sampled intravenous tolerance test, serum cytokine measurement, 7-day alimentary record performed 20 biopsy-proven NASH patients 45 age-, sex-, BMI-matched controls (30 insulin sensitive 15 resistant).Patients had impaired pancreatic beta-cell...
Background/Objectives It has been hypothesized that assuming most of the caloric intake later in day leads to metabolic disadvantages, but few studies are available on this topic. Aim our study was prospectively examine whether eating more daily at dinner an increased risk obesity, hyperglycemia, syndrome, and non-alcoholic fatty liver disease (NAFLD). Subjects/Methods 1245 non-obese, non-diabetic middle-aged adults from a population-based cohort underwent 3-day food record questionnaire...