A5038633429- Signaling Pathways in Disease
- Endoplasmic Reticulum Stress and Disease
- Photoacoustic and Ultrasonic Imaging
- Pancreatic function and diabetes
- Autophagy in Disease and Therapy
- Ultrasound Imaging and Elastography
- Ultrasound and Hyperthermia Applications
- Salivary Gland Tumors Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Thyroid Cancer Diagnosis and Treatment
- Retinal Imaging and Analysis
- Thyroid and Parathyroid Surgery
- Retinal and Optic Conditions
- Esophageal and GI Pathology
- Breast Lesions and Carcinomas
- AI in cancer detection
- Mosquito-borne diseases and control
- Venous Thromboembolism Diagnosis and Management
- Cerebral Venous Sinus Thrombosis
- Eosinophilic Esophagitis
- Digital Radiography and Breast Imaging
- Traditional Chinese Medicine Studies
- Toxoplasma gondii Research Studies
- Gastroesophageal reflux and treatments
- Vascular Tumors and Angiosarcomas
Dalian Medical University
2016-2023
First Affiliated Hospital of Dalian Medical University
2016-2023
Creative Commons
2020
Weatherford College
2020
Zero to Three
2020
Abstract Hepatocellular carcinoma (HCC) is refractory to chemotherapies, necessitating novel effective agents. The lysosome inhibitor Bafilomycin A1 (BafA1) at high concentrations displays cytotoxicity in a variety of cancers. Here we show that BafA1 nanomolar suppresses HCC cell growth both 2 dimensional (2D) and 3D cultures. induced cycle arrest the G1 phase triggered Cyclin D1 turnover cells dual-specificity tyrosine phosphorylation-regulated kinase 1B (DYRK1B) dependent manner. Notably,...
Abstract Background FK506-binding protein 9 (FKBP9) is amplified in high-grade gliomas (HGGs). However, the roles and mechanism(s) of FKBP9 glioma are unknown. Methods The expression clinical tissues was detected by immunohistochemistry (IHC). correlation between levels prognosis patients examined bioinformatic analysis. Glioblastoma (GBM) cell lines stably depleted were established using lentiviruses expressing shRNAs against FKBP9. effects on GBM cells determined cell-based analyses,...
Shear wave elastography (SWE) is a new ultrasonic technique for evaluating the hardness of living tissue by measuring propagation velocity shear in tissue, which characterized real-time, non-invasive and quantitative. The SWE can be used to diagnose lesions different tissues organs, quantitative measurement considered as more objective information about breast masses. Superb microvascular imaging (SMI) noninvasive Doppler ultrasound method, display blood flow with high spatial resolution...
Ultrasonography is the first choice for clinical diagnosis and differentiation of thyroid cancer Currently. However, due to complexity overlapping nature nodule sonograms, it remains difficult accurately identify nodules with atypical ultrasound characteristics. Previous studies showed that superb microvascular imaging (SMI) can detect tumor neovascularization differentiate benign from malignant nodules. results these have been contradictory low sample sizes. This meta-analysis tested...
Breast cancer being one of the most common malignant tumours among women, diagnostic modalities for early detection same become paramount importance. In this context, hand-held ultrasound (HHUS) and automated breast volume scanner (ABVS) could provide valuable information clinicians to diagnose diseases. This study aimed compare evaluate performance combined use HHUS ABVS differentiation benign lesions.A total 361 female patients, who underwent both examinations were included in study....
Myxofibrosarcoma most commonly arises as a slowly enlarging, painless mass. We describe an unusual case of low-grade myxofibrosarcoma in the axillary fossa, which infiltrated brachial plexus, artery, and vein, causing severe pain. The low incidence complex anatomical structure make imaging examination surgery face great challenges. To best our knowledge, such presentation that showed extreme infiltrative growth pattern presented pain has not been reported before. developed around...
As a novel ultrasound technique, superb microvascular imaging (SMI) can quickly, simply, and noninvasively study the distribution in tumor evaluate perfusion. Studies suggested that SMI is helpful for differentiation between benign malignant parotid tumors. However, results of these studies have been contradictory. Therefore, present meta-analysis aimed at determining accuracy differential diagnosis tumors.We will search PubMed, Web Science, Cochrane Library, Chinese biomedical databases...
Objective To investigate the retrobulbar hemodynamic changes in elderly patients with ischemic ophthalmopathy(IOP). Methods Three groups of 35 unilateral IOP(n=35 patients), 32 normal eye(n=32 volunteers)and 30 non-elderly eye(n=30 volunteers)were recruited our hospital for IOP or not, elderly(aged≥60)or not(aged <60). The peak systolic velocity(PSV), end-diastolic velocity(EDV), resistance index(RI), color Doppler blood stream spectrum form and arm-retinal circulation time(A-RCT)in...
Abstract Background: Functional dyspepsia (FD) is sub-categorized into postprandial distress syndrome (FD-PDS) and epigastric pain (FD-EPS). It a necessary to determine series of safe, feasible, non-invasive, economical assessment methods, which may detect more pathophysiological alterations guide corresponding treatment. Aim: To establish multi-dimensional detection (MDS) comprehensively evaluating the gastric motility FD patients verify clinical value MDS. Methods : FD-PDS (meeting Rome IV...
As a novel ultrasound technique, superb microvascular imaging can quickly, simply and noninvasively study the distribution in tumor evaluate perfusion. Studies suggested that is helpful for differentiation between benign malignant lymph nodes. However, results of these studies have been contradictory. Therefore, present meta-analysis aimed at determining accuracy differential diagnosis
Abstract Background Reflux esophagitis (RE) is a type of gastroesophageal reflux disease (GERD) which shows endoscopic injuries. Gastric function has been known as part mechanisms GERD. However, there still no comprehensive understandings. Methods 40 patients completed endoscopy and high-resolution manometry (HRM) who meet diagnostic criteria were enrolled in RE group, 34 healthy volunteers recruited control group. Both them evaluated gastric motility by multidimensional system including...