- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Dementia and Cognitive Impairment Research
- Physical Activity and Health
- Balance, Gait, and Falls Prevention
- Cerebral Palsy and Movement Disorders
- Telemedicine and Telehealth Implementation
- Heart Rate Variability and Autonomic Control
- Cardiac Health and Mental Health
- Mind wandering and attention
- Cardiovascular and exercise physiology
- Health Systems, Economic Evaluations, Quality of Life
- Botulinum Toxin and Related Neurological Disorders
- Health Policy Implementation Science
- Musculoskeletal pain and rehabilitation
- Nutritional Studies and Diet
- Diabetes Management and Research
- Muscle activation and electromyography studies
- Neurobiology of Language and Bilingualism
- Behavioral Health and Interventions
- Lipoproteins and Cardiovascular Health
- Neurological Disorders and Treatments
- Mental Health and Patient Involvement
- Urban Green Space and Health
- Pharmacovigilance and Adverse Drug Reactions
Hunter Medical Research Institute
2016-2025
University of Newcastle Australia
2016-2025
Hunter New England Local Health District
2015-2025
European Medicines Agency
2024
National Health and Medical Research Council
2017-2023
Australian Catholic University
2020-2021
Florey Institute of Neuroscience and Mental Health
2016-2021
Baker Heart and Diabetes Institute
2021
Janssen (Switzerland)
2021
The University of Melbourne
2020
Purpose: An enriched environment (EE) facilitates physical, cognitive and social activity in animal models of stroke. The aim this pilot study was to determine whether enriching the a mixed rehabilitation unit increased stroke patient activity. Methods: A non- randomized controlled trial conducted. Direct observation used difference change cognitive, or any over 2 weeks patients exposed an versus non-enriched environment. Results: Stroke EE (n = 15) were 1.2 (95% CI 1.0–1.4) times more...
Objectives: To determine whether an enriched environment embedded in acute stroke unit could increase activity levels patients and reduce adverse events. Design: Controlled before–after pilot study. Setting: An a regional Australian hospital. Participants: Acute admitted during (a) initial usual care control period, (b) period (c) sustainability period. Intervention: Usual participants received one-on-one allied health intervention nursing care. The were provided stimulating resources,...
Objective: To determine physical, cognitive and social activity levels of stroke patients undergoing rehabilitation, whether these changed over time. Design: Observational study using behavioural mapping techniques to record patient 12 hours on one weekday weekend day at baseline (week 1) again two weeks later 2). Setting: A 20-bed mixed rehabilitation unit. Subjects: Fourteen patients. Interventions: None. Main measures: Percentage spent in any or activities. Level independence the...
Clinician interest in the role of tablet technology commercially available devices (i.e. iPads) following stroke is rising. Tablets have potential to encourage engagement therapeutic activities. We aimed explore survivor acceptability and experience use during first three months recovery.A qualitative study using an inductive thematic approach incorporating process constant comparison was utilized collect analyse data.Community dwelling survivors metropolitan Newcastle, New South Wales,...
Data highlight the importance of undertaking intense and frequent repetition activities within stroke rehabilitation to maximise recovery. An enriched environment (EE) provides a medium in which these can be performed enhanced recovery achieved. EE has been shown promote neuroplasticity animal models stroke, facilitating motor cognitive function. However, benefit enriching survivors remains unknown.To qualitatively explore survivors' experience implementation exposure an typical setting,...
Background Stroke survivors sit for long periods each day. Uninterrupted sitting is associated with increased risk of cardiovascular disease. Breaking up uninterrupted frequent, short bouts light-intensity physical activity has an immediate positive effect on blood pressure and plasma clotting factors in healthy, overweight, type 2 diabetic populations. Aim We examined the fibrinogen stroke survivors. Methods Prespecified secondary analyses from a three-armed randomized, within-participant,...
Background: Improving physical activity levels and diet quality are important for secondary stroke prevention. Aim: To test the feasibility safety of 6-month, co-designed telehealth-delivered interventions to increase improve quality. Methods: A 2 × factorial trial (physical (PA); (DIET); PA + DIET; control) randomized, open-label, blinded endpoint trial. Primary outcomes were safety. Secondary included risk factors (blood pressure, self-report (International Physical Activity Questionnaire...
Rationale Environmental enrichment, a paradigm investigated extensively in animal models, is an intervention, which by design facilitates motor, sensory, social, and cognitive activity. It has been shown to improve poststroke motor function models of stroke. This the first study attempt translate this intervention from laboratory clinical setting. Aims The overall aim pilot test feasibility using environmental enrichment with stroke patients rehabilitation enrich environment survivors ward...
Background Environmental enrichment involves organization of the environment and provision equipment to facilitate engagement in physical, cognitive, social activities. In animals with stroke, it promotes brain plasticity recovery. Aims To assess feasibility safety a patient-driven model environmental incorporating access communal individual enrichment. Methods A nonrandomized cluster trial blinded measurement involving people stroke ( n = 193) four rehabilitation units was carried out....
Many stroke survivors require care from informal carers such as family members and friends who may experience adverse impacts. This study aimed to qualitatively explore the unmet needs of survivors, their preferences for interventions support services. We conducted 24 semi-structured, qualitative interviews with Hunter region, Australia. Inductive thematic analysis was used in context a needs-led framework identify key themes needs. Key identified by this centred on four main themes: (1)...
Stroke is a life-altering event for survivors. While improving diet quality associated with reduced stroke risk, the post-stroke effects often make meal preparation difficult. There lack of published research on culinary nutrition programmes tailored to survivors' recovery journey. This study outlines co-design process programme aimed at promoting uptake Mediterranean-style people who have had stroke. Utilising Integrated Knowledge Translation (IKT) framework, exploratory interviews and...
One-fifth of the 101 million stroke survivors worldwide experience another within following five years. Research indicates that lifestyle risk factors account for 90% (similar to recurrent stroke) risk, and improving diet quality is a promising strategy (1) . Synthesised research suggests adopting Mediterranean-style (2) with reduced sodium intake (3) can enhance cardiovascular health, which may be beneficial secondary prevention. Our previous ENAbLE trial, co-designed telehealth exercise...